Phase 1 · Jacksonville area, FL
Phase 1 clinical trials in Jacksonville area, FL
26 recruiting studies have a site in the Jacksonville area. This page includes nearby cities such as Orange Park, Jacksonville Beach, Ponte Vedra Beach, St. Augustine.
26 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteersPhase 1/Phase 2
Study of XmAb942 in Healthy Participants and Participants With Ulcerative Colitis
Xencor, Inc.
- Location
- Bradenton, FL + 27 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingHealthy volunteersPhase 1/Phase 2
Safety, PK and Biodistribution of 18F-OP-801 in Patients With ALS, AD, MS, PD and Healthy Volunteers
Ashvattha Therapeutics, Inc.
- Location
- Jacksonville, FL + 2 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 1/Phase 2Overnight stay mentioned
Study is to Assess the Safety and Tolerability of VTx-002 in Participants With ALS
Vector Y Therapeutics
- Location
- Jacksonville, FL + 3 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1Overnight stay mentioned
A Safety and Tolerability Study of HJB647 in Heart Failure Participants With Reduced Ejection Fraction
Novartis Pharmaceuticals
- Location
- Bradenton, FL + 4 other US sites
- Eligibility basics
- Ages 18–100
- RecruitingHealthy volunteersPhase 1
Safety and Pharmacokinetics Study of PGT121.414.LS Alone and in Combination With VRC07-523LS in Infants Exposed to HIV-1
National Institute of Allergy and Infectious Diseases (NIAID)
- Location
- Jacksonville, FL + 4 other US sites
- Eligibility basics
- Any age listed
- RecruitingHealthy volunteersPhase 1/Phase 2
Retina is a Marker for Cerebrovascular Heath
Mayo Clinic
- Location
- Jacksonville, FL
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
A Study in Adult Males With X-linked Congenital Nephrogenic Diabetes Insipidus to Test the Effects of NDI-5001 Given for Multiple Days and to Test How NDI-5001 is Tolerated and Taken up in the Body
Otsuka Pharmaceutical Development & Commercialization, Inc.
- Location
- Jacksonville, FL + 1 other US site
- Eligibility basics
- Ages 18–55 · Men only
- RecruitingPhase 1/Phase 2
RESET-MG: A Study to Evaluate the Safety and Efficacy of CABA-201 in Participants With Generalized Myasthenia Gravis
Cabaletta Bio
- Location
- Jacksonville, FL + 16 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 1
Evaluation of the Tolerability of Cagrilintide in Participants Not Tolerating GLP-1-RA Therapies Due to Gastrointestinal Adverse Events
Novo Nordisk A/S
- Location
- Fleming Island, FL + 9 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
Safety, Tolerability and Pharmacokinetics of AZD1613 in Adults With Autosomal Dominant Polycystic Kidney Disease
AstraZeneca
- Location
- Jacksonville, FL + 4 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 1/Phase 2
RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus
Cabaletta Bio
- Location
- Jacksonville, FL + 17 other US sites
- Eligibility basics
- Ages 12–65
- RecruitingPhase 1/Phase 2
A Study of AAVB-039 in Participants With Stargardt Disease (STGD1)
AAVantgarde Bio Srl
- Location
- Jacksonville, FL + 7 other US sites
- Eligibility basics
- Ages 8–55
- RecruitingPhase 1/Phase 2
A Study of TSRA-196 in Adults With PiZZ Alpha-1 Antitrypsin Deficiency (AATD)
Tessera Therapeutics, Inc.
- Location
- Jacksonville, FL + 4 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 1
A Safety and Tolerability Trial Evaluating CTX310 in Participants With Refractory Dyslipidemias
CRISPR Therapeutics AG
- Location
- Hialeah, FL + 7 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1/Phase 2
CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D)
COUR Pharmaceutical Development Company, Inc.
- Location
- Fort Myers, FL + 44 other US sites
- Eligibility basics
- Ages 12–35
- RecruitingPhase 1
A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease
Allogene Therapeutics
- Location
- Jacksonville, FL + 15 other US sites
- Eligibility basics
- Ages 18–74
- RecruitingPhase 1
A Study of VERVE-102 in Patients With Familial Hypercholesterolemia or Premature Coronary Artery Disease
Verve Therapeutics, Inc.
- Location
- Boca Raton, FL + 9 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 1/Phase 2
AMT-260 Gene Therapy Study in Adults With Unilateral Refractory Mesial Temporal Lobe Epilepsy
UniQure Biopharma B.V.
- Location
- Jacksonville, FL + 15 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1
A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4954 in Healthy Adult Participants With or Without Elevated Lipoprotein (a) (Lp[a]) Levels, and Participants With Dyslipidemia
AstraZeneca
- Location
- Inverness, FL + 5 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 1/Phase 2
Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Adults With Moderate to Severe Acne
Sanofi Pasteur, a Sanofi Company
- Location
- Boynton Beach, FL + 78 other US sites
- Eligibility basics
- Ages 18–45
- RecruitingPhase 1/Phase 2
A Study of DB-OTO, an Adeno-Associated Virus (AAV) Based Gene Therapy, in Children/Infants, Adolescents and Adults With Hearing Loss Due to Otoferlin Mutations
Regeneron Pharmaceuticals
- Location
- Jacksonville, FL + 8 other US sites
- Eligibility basics
- Any age listed
- RecruitingPhase 1/Phase 2
Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Participants With Mild Acne
Sanofi Pasteur, a Sanofi Company
- Location
- Brandon, FL + 3 other US sites
- Eligibility basics
- Ages 18–45
- RecruitingEarly Phase 1
VTP-1000 in Adults With Celiac Disease
Barinthus Biotherapeutics
- Location
- Jacksonville, FL + 15 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 1/Phase 2
Study of EXE-346 Live Biotherapeutic to Reduce High Bowel Movement Frequency in Subjects With an IPAA (PROF)
Exegi Pharma, LLC
- Location
- Jacksonville, FL + 7 other US sites
- Eligibility basics
- Ages 18+
Who these studies look for
Phase 1 studies often have narrow eligibility: specific age and weight ranges, no recent participation in another study, no nicotine, and limits on medications. Some Phase 1 studies recruit patients rather than healthy volunteers, so check each listing.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.