Phase 1 · Orlando area, FL
Phase 1 clinical trials in Orlando area, FL
55 recruiting studies have a site in the Orlando area. This page includes nearby cities such as Winter Park, Kissimmee, Altamonte Springs, Sanford.
55 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteersPhase 1
A Study of LY4006895 in Healthy Participants With Early Symptomatic Alzheimer's Disease (AD)
Eli Lilly and Company
- Location
- Lady Lake, FL + 5 other US sites
- Eligibility basics
- Ages 45–85
- RecruitingHealthy volunteersPhase 1
A Study of Eloralintide (LY3841136) in Participants With Different Levels of Liver Damage and in Participants With Healthy Livers.
Eli Lilly and Company
- Location
- Orlando, FL + 1 other US site
- Eligibility basics
- Ages 18–85
- RecruitingHealthy volunteersPhase 1/Phase 2
A Phase 1/2a Study of DB-2304 in Healthy Adults and SLE/CLE Participants
DualityBio Inc.
- Location
- Clearwater, FL + 4 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingHealthy volunteersPhase 1
A Study of Mirikizumab Solution (LY3074828) in Healthy Participants
Eli Lilly and Company
- Location
- Daytona Beach, FL + 4 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 1
A Study to Learn About the Medicine Called PF-08653944 in People With and Without Reduced Liver Function
Pfizer
- Location
- Miami Lakes, FL + 2 other US sites
- Eligibility basics
- Ages 18–74
- RecruitingHealthy volunteersPhase 1
A Study to Learn How the Body Processes the Study Medicine Called Vepdegestrant in People With Loss of Liver Function
Pfizer
- Location
- Miami, FL + 3 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingHealthy volunteersPhase 1
Clofutriben Pharmacokinetics in Patients With Impaired Renal Function
Sparrow Pharmaceuticals
- Location
- Orlando, FL
- Eligibility basics
- Ages 18–83
- RecruitingHealthy volunteersPhase 1
Pharmacokinetics (PK) and Safety of Zanzalintinib in Participants With Moderate Hepatic Impairment (HI)
Exelixis
- Location
- Orlando, FL + 1 other US site
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1Overnight stay mentioned
A Safety and Tolerability Study of HJB647 in Heart Failure Participants With Reduced Ejection Fraction
Novartis Pharmaceuticals
- Location
- Bradenton, FL + 4 other US sites
- Eligibility basics
- Ages 18–100
- RecruitingPhase 1Overnight stay mentioned
A Study of LTX-001 In Adult Participants With Acute Exacerbation of Schizophrenia
Leal Therapeutics, Inc
- Location
- DeLand, FL + 9 other US sites
- Eligibility basics
- Ages 18–55
- RecruitingHealthy volunteersEarly Phase 1
Quadriceps Motor Unit Adaptation to Simulated Knee Injury
University of Central Florida
- Location
- Orlando, FL
- Eligibility basics
- Ages 18–30
- RecruitingPhase 1
A Study of CLN-978, a Subcutaneously Administered CD19-directed T Cell Engager, in Subjects With Systemic Lupus Erythematosus
Cullinan Therapeutics Inc.
- Location
- Orlando, FL + 10 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 1
A Study to Assess Adverse Events, How the Drug Moves Through the Body and Effectiveness of Intravenous Infusions and Subcutaneous Injections of ABBV-519 in Adult Participants With Systemic Lupus Erythematosus (SLE) or…
AbbVie
- Location
- Clearwater, FL + 11 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1
Safety, Tolerability and Pharmacokinetics of AZD1613 in Adults With Autosomal Dominant Polycystic Kidney Disease
AstraZeneca
- Location
- Jacksonville, FL + 4 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 1
Study to Evaluate the Maximal Use of Ruxolitinib Cream in Adult and Adolescent Participants With Hidradenitis Suppurativa
Incyte Corporation
- Location
- Sanford, FL + 15 other US sites
- Eligibility basics
- Ages 12–75
- RecruitingPhase 1/Phase 2
Clinical Study of SNK01 in Participants With Moderate Alzheimer's Disease
NKGen Biotech, Inc.
- Location
- Maitland, FL + 5 other US sites
- Eligibility basics
- Ages 40–85
- RecruitingPhase 1
A Safety and Tolerability Trial Evaluating CTX310 in Participants With Refractory Dyslipidemias
CRISPR Therapeutics AG
- Location
- Hialeah, FL + 7 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1/Phase 2
A Study to Assess the Safety and Effects of ABBV-1758 Following Subcutaneous or Intravenous Injections in Participants With Alzheimer's Disease
AbbVie
- Location
- Bradenton, FL + 10 other US sites
- Eligibility basics
- Ages 50–90
- RecruitingPhase 1
An Open Label Dose Escalation Study of VY1706 in Participants With Early Alzheimer's Disease
Voyager Therapeutics
- Location
- Maitland, FL
- Eligibility basics
- Ages 30–80
- RecruitingPhase 1
A Study to Find Out How Nusinersen is Processed in the Body When Given Through the ThecaFlex DRx™ System in Adult and Pediatric Participants With Spinal Muscular Atrophy (PIERRE-PK)
Biogen
- Location
- Orlando, FL + 11 other US sites
- Eligibility basics
- Ages 3+
- RecruitingPhase 1
A Study of VERVE-102 in Patients With Familial Hypercholesterolemia or Premature Coronary Artery Disease
Verve Therapeutics, Inc.
- Location
- Boca Raton, FL + 9 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 1
A First-In-Human Study of LY3954068 in Participants With Early Symptomatic Alzheimer's Disease
Eli Lilly and Company
- Location
- Maitland, FL + 4 other US sites
- Eligibility basics
- Ages 50–85
- RecruitingPhase 1
A Study of CLN-978, a Subcutaneously Administered CD19-directed T Cell Engager, in Subjects With Sjogren's Disease
Cullinan Therapeutics Inc.
- Location
- Orlando, FL + 5 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
A Study of DB-OTO, an Adeno-Associated Virus (AAV) Based Gene Therapy, in Children/Infants, Adolescents and Adults With Hearing Loss Due to Otoferlin Mutations
Regeneron Pharmaceuticals
- Location
- Jacksonville, FL + 8 other US sites
- Eligibility basics
- Any age listed
Who these studies look for
Phase 1 studies often have narrow eligibility: specific age and weight ranges, no recent participation in another study, no nicotine, and limits on medications. Some Phase 1 studies recruit patients rather than healthy volunteers, so check each listing.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.