Phase 1 · Florida
Phase 1 clinical trials in Florida
191 studies have at least one recruiting site in Florida. Phase 1 (and early Phase 1) trials are usually the first time a medicine is studied in people. They are typically small, closely monitored, and many are run in dedicated research units, sometimes with overnight stays.
191 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 1/Phase 2
A Study of VV-14303 for the Treatment of Metabolic Dysfunction-associated Steatohepatitis (MASH)
Kriya Therapeutics, Inc.
- Location
- Lady Lake, FL
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1/Phase 2
AMT-260 Gene Therapy Study in Adults With Unilateral Refractory Mesial Temporal Lobe Epilepsy
UniQure Biopharma B.V.
- Location
- Jacksonville, FL + 15 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1
A First-In-Human Study of LY3954068 in Participants With Early Symptomatic Alzheimer's Disease
Eli Lilly and Company
- Location
- Maitland, FL + 4 other US sites
- Eligibility basics
- Ages 50–85
- RecruitingPhase 1
A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4954 in Healthy Adult Participants With or Without Elevated Lipoprotein (a) (Lp[a]) Levels, and Participants With Dyslipidemia
AstraZeneca
- Location
- Inverness, FL + 5 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 1/Phase 2
4D-150 in Patients With Neovascular (Wet) Age-Related Macular Degeneration
4D Molecular Therapeutics
- Location
- Fort Lauderdale, FL + 19 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 1/Phase 2
Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Adults With Moderate to Severe Acne
Sanofi Pasteur, a Sanofi Company
- Location
- Boynton Beach, FL + 78 other US sites
- Eligibility basics
- Ages 18–45
- RecruitingPhase 1
A Study of CLN-978, a Subcutaneously Administered CD19-directed T Cell Engager, in Subjects With Sjogren's Disease
Cullinan Therapeutics Inc.
- Location
- Orlando, FL + 5 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
A Trial Evaluating Safety, Tolerability and Efficacy of CTX340 in Participants With Hypertension
CRISPR Therapeutics AG
- Location
- Port Orange, FL
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1
A Study to Assess Adverse Events, How the Drug Moves Through the Body and Effectiveness of Intravenous Infusions of ABBV-319 in Adult Participants With Systemic Lupus Erythematosus (SLE), Sjogren's Disease (SjD) and…
AbbVie
- Location
- Margate, FL + 4 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1/Phase 2
A Phase 1/2 Study of NKX019 in Subjects With Immune-Mediated Diseases (Ntrust-2)
Nkarta, Inc.
- Location
- Gainesville, FL + 14 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1/Phase 2
A Study of DB-OTO, an Adeno-Associated Virus (AAV) Based Gene Therapy, in Children/Infants, Adolescents and Adults With Hearing Loss Due to Otoferlin Mutations
Regeneron Pharmaceuticals
- Location
- Jacksonville, FL + 8 other US sites
- Eligibility basics
- Any age listed
- RecruitingPhase 1/Phase 2
Study of Aritinercept in Patients With Generalized Myasthenia Gravis
Aurinia Pharmaceuticals Inc.
- Location
- Altamonte Springs, FL + 9 other US sites
- Eligibility basics
- Ages 18–85
- RecruitingPhase 1
Study of BHV-1300 in Graves' Disease
Biohaven Therapeutics Ltd.
- Location
- Miami, FL + 9 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingEarly Phase 1
A Study to Investigate Safety and Efficacy of KB111 for the Treatment of Hailey-Hailey Disease
Krystal Biotech, Inc.
- Location
- Miami, FL
- Eligibility basics
- Ages 12+
- RecruitingPhase 1/Phase 2
A Study to Assess the Effects of ACI-24.060 in Alzheimer's Disease and in Down Syndrome (ABATE Study)
AC Immune SA
- Location
- Lady Lake, FL + 3 other US sites
- Eligibility basics
- Ages 35–85
- RecruitingPhase 1/Phase 2
Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Participants With Mild Acne
Sanofi Pasteur, a Sanofi Company
- Location
- Brandon, FL + 3 other US sites
- Eligibility basics
- Ages 18–45
- RecruitingPhase 1
A Study to Learn if Bimekizumab Given in Different Ways is Safe and Moves Similarly Throughout the Body Over Time in Adults
UCB Biopharma SRL
- Location
- Ormond Beach, FL + 29 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
A Phase 1b/2 Study of CAR T Cell Therapy Targeting CD19 and BCMA in Participants With Relapsed or Refractory AL Amyloidosis.
Alexion Pharmaceuticals, Inc.
- Location
- Tampa, FL + 9 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
A Study on the Safety and Immune Response of Investigational mRNA Seasonal Flu/COVID-19 Combination Vaccine in Adults
GlaxoSmithKline
- Location
- Miami, FL + 11 other US sites
- Eligibility basics
- Ages 65–85
- RecruitingPhase 1
Study of BHV-1400 in IgA Nephropathy
Biohaven Therapeutics Ltd.
- Location
- Miami Lakes, FL + 13 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingEarly Phase 1
VTP-1000 in Adults With Celiac Disease
Barinthus Biotherapeutics
- Location
- Jacksonville, FL + 15 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 1
A Study to Assess the Safety and Pharmacokinetics of INCB123667 When Administered Orally to Adult Participants With Severe Renal Impairment or End Stage Renal Disease
Incyte Corporation
- Location
- Miami Lakes, FL + 1 other US site
- Eligibility basics
- Ages 18–85
- RecruitingPhase 1
R-3750 in Patients With Mild to Moderate Ulcerative Colitis
Rise Therapeutics LLC
- Location
- Miami, FL + 4 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 1
R-2487 in Patients With Rheumatoid Arthritis
Rise Therapeutics LLC
- Location
- Doral, FL + 5 other US sites
- Eligibility basics
- Ages 18–75
Who these studies look for
Phase 1 studies often have narrow eligibility: specific age and weight ranges, no recent participation in another study, no nicotine, and limits on medications. Some Phase 1 studies recruit patients rather than healthy volunteers, so check each listing.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Are Phase 1 trials riskier?
Every study carries risk. Phase 1 studies involve less human data about the product, which is why they are closely monitored. The informed consent document explains the known risks; read it carefully and ask questions before signing.
Why do some Phase 1 studies include overnight stays?
Staying in the unit lets staff dose on a precise schedule and collect samples around the clock. Where a record mentions an inpatient stay we flag it on the listing.