Phase 1 · Minneapolis area, MN
Phase 1 clinical trials in Minneapolis area, MN
25 recruiting studies have a site in the Minneapolis area. This page includes nearby cities such as Saint Paul, St. Paul, Bloomington, Edina.
25 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteersPhase 1Overnight stay mentioned
A Study to Learn How the Body Processes the Study Medicine PF-07328948 in People With Reduced Kidney Function
Pfizer
- Location
- Saint Paul, MN + 3 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingHealthy volunteersPhase 1
A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4248 in Healthy Participants and Participants With Chronic Kidney Disease and Type 2 Diabetes and to Assess Home Measurements of…
AstraZeneca
- Location
- Saint Paul, MN + 3 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingHealthy volunteersPhase 1
Safety, Tolerability, and Pharmacokinetics of ASCT-83 in Healthy Adults
Alcamena Stem Cell Therapeutics
- Location
- Saint Paul, MN
- Eligibility basics
- Ages 18–64
- RecruitingHealthy volunteersPhase 1
Optimizing Transcranial Magnetic Stimulation for Stimulant Use Disorder
University of Minnesota
- Location
- Minneapolis, MN
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersEarly Phase 1
JIT: Effect of Pain on DT in TMD
University of Minnesota
- Location
- Minneapolis, MN
- Eligibility basics
- Ages 21–65
- RecruitingHealthy volunteersPhase 1
Microelectrode Recordings From the Vagus Nerve in Awake Humans
University of Minnesota
- Location
- Minneapolis, MN
- Eligibility basics
- Ages 18–40
- RecruitingHealthy volunteersEarly Phase 1
Stimulating After Recovery From Traumatic Brain Injury
University of Minnesota
- Location
- Minneapolis, MN
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersEarly Phase 1
Trigeminal Evoked Responses to Improve Rhizotomy
University of Minnesota
- Location
- Minneapolis, MN
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
A Clinical Study of Letermovir (MK-8228) in Children and Adolescents Who Receive a Kidney Transplant (KT) (MK-8228-077)
Merck Sharp & Dohme LLC
- Location
- Minneapolis, MN + 20 other US sites
- Eligibility basics
- Up to age 17
- RecruitingPhase 1/Phase 2
ATTUNE: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Intrathecally-Administered ION440 in Participants With Methyl CpG Binding Protein 2 (MECP2) Duplication Syndrome (MDS)
Ionis Pharmaceuticals, Inc.
- Location
- Saint Paul, MN + 7 other US sites
- Eligibility basics
- Ages 2–65 · Men only
- RecruitingPhase 1/Phase 2
RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus
Cabaletta Bio
- Location
- Minneapolis, MN + 17 other US sites
- Eligibility basics
- Ages 12–65
- RecruitingPhase 1/Phase 2
A Study of Oral Nuvisertib (TP-3654) in Patients With Myelofibrosis
Sumitomo Pharma America, Inc.
- Location
- Minneapolis, MN + 29 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
A Study to Learn About the Study Medicine Called Zavegepant (PF-07930207) in Children With a History of Migraine
Pfizer
- Location
- Minneapolis, MN + 10 other US sites
- Eligibility basics
- Ages 6–11
- RecruitingPhase 1/Phase 2
Safety, PK/PD, and Exploratory Efficacy Study of AMT-191 in Classic Fabry Disease
UniQure Biopharma B.V.
- Location
- Minneapolis, MN + 9 other US sites
- Eligibility basics
- Ages 18–65 · Men only
- RecruitingPhase 1/Phase 2
CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D)
COUR Pharmaceutical Development Company, Inc.
- Location
- Minneapolis, MN + 44 other US sites
- Eligibility basics
- Ages 12–35
- RecruitingPhase 1/Phase 2
Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Adults With Moderate to Severe Acne
Sanofi Pasteur, a Sanofi Company
- Location
- Minneapolis, MN + 78 other US sites
- Eligibility basics
- Ages 18–45
- RecruitingPhase 1/Phase 2
AAV Gene Therapy Clinical Study in Adult Classic PKU (PHEdom)
NGGT INC.
- Location
- Minneapolis, MN + 4 other US sites
- Eligibility basics
- Ages 18–55
- RecruitingPhase 1
Study to Evaluate the Safety and Efficacy of CSB-001 Ophthalmic Solution 0.1% in Subjects With Limbal Stem Cell Deficiency
Claris Biotherapeutics, Inc.
- Location
- Minnetonka, MN + 5 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
A Phase 1/2 Study of NKX019 in Subjects With Immune-Mediated Diseases (Ntrust-2)
Nkarta, Inc.
- Location
- Minneapolis, MN + 14 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1
ISP-001: Sleeping Beauty Transposon-Engineered B Cells for MPS I
Immusoft of CA, Inc.
- Location
- Minneapolis, MN + 1 other US site
- Eligibility basics
- Ages 10+
- RecruitingPhase 1
A Phase 1 Study of FT819 in B-cell Mediated Autoimmune Disease
Fate Therapeutics
- Location
- Minneapolis, MN + 15 other US sites
- Eligibility basics
- Ages 12–70
- RecruitingPhase 1/Phase 2
A Study to Investigate the Safety of DSP-3077 After a Unilateral Eye Injection in Male and Female Participants 18 Years of Age or Older With Retinitis Pigmentosa
Sumitomo Pharma America, Inc.
- Location
- Minneapolis, MN + 1 other US site
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
Study to Evaluate the Safety and Efficacy of CSB-001 Ophthalmic Solution 0.1% in Subjects With Corneal Scars
Claris Biotherapeutics, Inc.
- Location
- Minnetonka, MN + 6 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 1/Phase 2
A Study Comparing KB801 Verse Placebo in Patients With Stage 2 or 3 Neurotrophic Keratitis
Krystal Biotech, Inc.
- Location
- Alexandria, MN + 6 other US sites
- Eligibility basics
- Ages 18+
Who these studies look for
Phase 1 studies often have narrow eligibility: specific age and weight ranges, no recent participation in another study, no nicotine, and limits on medications. Some Phase 1 studies recruit patients rather than healthy volunteers, so check each listing.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.