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A Randomized Controlled Trial Testing the Effect of the Youth Mindful Awareness Program on Negative Affect (YMAP2).

Vanderbilt University · with National Institute of Mental Health (NIMH) · NCT06526052

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 12–17 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
360
US sites recruiting
3
Study start
April 1, 2024
Record last updated
August 20, 2025

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The goal of this randomized clinical trial is to compare the effects of an online mindfulness program to an active supportive comparison condition and a no-intervention control group on reducing and preventing mood and anxiety symptoms in at-risk youth. Youth who are high on trait negative affect will be randomized to one of the three conditions. The primary outcomes of interest are reductions in momentary negative affect and internalizing problems in adolescents ages 12 to 17 years old. All participants will be evaluated prior to being randomized, after the 9-session intervention period, and at a 6-month follow-up.

The first hypothesis is that the mindfulness intervention will predict decreases in stressor-reactive momentary negative affect and internalizing symptoms. The second hypothesis is that changes in momentary negative affect will partially account for the effects of the mindfulness intervention on internalizing symptoms.

Being studied: Mindfulness Program; Active Comparator

Conditions: Prevention; Control

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Ages 12, 13, 14, 15, 16, 17
  • Parental Consent
  • Participant Assent
  • Live in Illinois, California, or Tennessee

Exclusion Criteria

  • current diagnosis of an anxiety or depressive disorder with significant clinical impairment
  • current alcohol or substance use disorder
  • current serious suicidal ideation or behavior
  • lifetime diagnosis of bipolar disorder, schizophrenia, autism, conduct disorder, or developmental delay
  • reading level below 4th grade
  • not English speaking at a level that would allow them to participate in the intervention and assessments

Recruiting US locations

  • University of California, Los Angeles

    Los Angeles, CA 90095

    Site contact: Michelle G Craske, PhD · 310-825-8403 · MCraske@mednet.ucla.edu

  • Northwestern University

    Evanston, IL 60208

    Site contact: Richard E Zinbarg, PhD · 847-467-2290 · rzinbarg@northwestern.edu

  • Vanderbilt University

    Nashville, TN 37203-5721

    Site contact: Judith A Garber, PhD · 615-330-5605 · jgarber.vanderbilt@gmail.com

Study contacts (from the official record)

  • Judith A Garber, PhD · 6153305605 · jgarber.vanderbilt@gmail.com
  • Steven D Hollon, PhD · 6153305604 · steven.d.hollon@vanderbilt.edu
A Randomized Controlled Trial Testing the Effect of the Youth… (NCT06526052) | Bored Studies