A Study to Evaluate Etrasimod Treatment in Adolescents With Ulcerative Colitis
Pfizer · with Arena is a wholly owned subsidiary of Pfizer · NCT05287126
Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.
Key facts
- Compensation
- Not posted. Ask the study team before screening.
- Who can join
- Ages 12–17 · All sexes
- Healthy volunteers
- Not accepted (a condition is required)
- Study type
- Interventional · Phase 2
- Target enrollment
- 36
- US sites recruiting
- 12
- Study start
- December 16, 2022
- Record last updated
- July 8, 2026
Status re-checked against ClinicalTrials.gov within the last 12 hours.
What the study is about
The purpose of this study is to determine the safety, efficacy, and pharmacokinetics (PK) of etrasimod for the treatment of moderately to severely active ulcerative colitis in adolescents (≥ 12 years up to \< 18 years of age). Participants who will complete the total 52-week treatment period will have the opportunity to continue in a Long-Term Extension (LTE) Period of up to 4 years (5 years after study enrollment).
Being studied: Etrasimod
Conditions: Ulcerative Colitis
Eligibility criteria
Copied from the official record. The study team makes the final decision at screening.
Show full criteria
Inclusion criteria
- Have a diagnosis of ulcerative colitis (UC) that is moderately to severely active
- Participants are permitted to be receiving a therapeutic dose of select UC therapies
Exclusion criteria
- Severe extensive colitis
- Diagnosis of Crohn's disease (CD) or indeterminate colitis or the presence or history of a fistula consistent with CD
- Diagnosis of microscopic colitis, ischemic colitis, or infectious colitis
Recruiting US locations
Valley View Wellness Medical Center
Garden Grove, CA 92845
University of California San Francisco,
San Francisco, CA 94158
University of California San Francisco
San Francisco, CA 94158
University of California,San Francisco Pediatric ClinicalResearch Center (PCRC)
San Francisco, CA 94158
Arnold Palmer Hospital - Center for Digestive Health and Nutrition
Orlando, FL 32806
University of Chicago Medical Center
Chicago, IL 60637
Boston Children's Hospital
Boston, MA 02115
William Beaumont Hospital/Corewell Health - East
Royal Oak, MI 48073
William Beaumont Hospitals Reference Laboratory
Royal Oak, MI 48073
University Hospitals Cleveland Medical Center Rainbow Babies & Children's Hospital
Cleveland, OH 44106
University Hospitals Cleveland Medical Center
Cleveland, OH 44106
ACT-Midwest G1
Abilene, TX 79606
Study contacts (from the official record)
- Pfizer CT.gov Call Center · 1-800-718-1021 · ClinicalTrials.gov_Inquiries@pfizer.com