Skip to content
Bored Studies
RecruitingAccepts healthy volunteers

AMD and Validation Rod-Meditated Dark Adaptation With Everyday Task Performance

Duke University · with Boehringer Ingelheim, StreetLab Vision · NCT06619405

View Study & Apply (opens in a new tab)

Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 50–89 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
100
US sites recruiting
1
Study start
August 15, 2025
Record last updated
August 10, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The goal is to conduct a cross-sectional, single timepoint study on older adults with early and intermediate AMD, and with subretinal drusenoid deposits (SDD), and those in normal health, establishing an association between dark adaptation and reading performance under dim illumination, both which depend on rod photoreceptors.

Being studied: Streetlab VR

Conditions: Age-Related Macular Degeneration

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Capable and willing to provide consent
  • Has been diagnosed with early, intermediate dry age-related macular degeneration or geographic atrophy or has a healthy macular for controls
  • At least 50 years of age

Exclusion Criteria

  • Unable or unwilling to give consent or unable to read consent since the study involves testing which requires reading
  • Under 50 years of age
  • Presence of dense cataracts in the study eye (s) that can affect visual function tests
  • Presence of glaucoma requiring treatment during the study and/or visual field defects
  • Previous retinal laser or surgical therapy in the study eye(s)
  • Previous retinal laser or surgical therapy in the study eye(s)
  • Any other ocular condition requiring long-term therapy or surgery during the study
  • The participant has photographically significant corneal or media opacities in either eye that would preclude adequate ophthalmic imaging and functional testing
  • Diagnosis of nystagmus that will interfere with testing
  • High myopia -8 Diopters or more severe
  • The participant has, in the opinion of the Investigator, any physical or mental condition that would increase the risk of participation in the study or may interfere with the study procedures, evaluations, and outcome assessments.

Recruiting US locations

Study contacts (from the official record)

  • Eleonora Lad, MD, PhD · 919-684-4359 · nora.lad@duke.edu
  • Alice Ventura · 919-681-6585 · alice.ventura@duke.edu
All healthy volunteers studies in North Carolina →
AMD and Validation Rod-Meditated Dark Adaptation With Everyday… (NCT06619405) | Bored Studies