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RecruitingAccepts healthy volunteersEarly Phase 1

Cardiovascular Effects of Very Low Nicotine Content Cigarettes

Wake Forest University Health Sciences · NCT05707871

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 21+ · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Early Phase 1
Target enrollment
49
US sites recruiting
1
Study start
April 4, 2023
Record last updated
August 28, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The study is measuring Cardiovascular effects of very low nicotine content cigarettes on daily and non-daily smokers

Being studied: SPECTRUM cigarettes; usual brand of Cigarettes

Conditions: Tobacco Use

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Self-reported cigarette smoking at least once in the past 30 days
  • ≥21 years old
  • Willingness to smoke research cigarettes or usual brand cigarettes during lab visit.
  • Ability to speak, comprehend, and read English sufficiently to complete study procedures

Exclusion Criteria

  • Self-reported diagnosis of cardiovascular diseases like coronary artery disease, stroke, peripheral artery disease, cardiac arrhythmia, pulmonary embolism \& blood clots in legs and arm in the past 3 months
  • Body temperature ≥ 100.4˙F
  • Unstable health conditions interfering with electrocardiogram (ECG) measurements
  • Self-reported diagnosis of hyperthyroidism or thyrotoxicosis
  • Currently pregnant (as indicated by urine pregnancy test at the start of laboratory visit) or breastfeeding.
  • Currently seeking treatment to quit smoking

Recruiting US locations

  • Wake Forest University Health Sciences

    Winston-Salem, NC 27157

    Site contact: Maria Anwar, MS · 802-922-3343 · manwar@wakehealth.edu

Study contacts (from the official record)

  • Maria Anwar, MS · 802-922-3343 · manwar@wakehealth.edu
Cardiovascular Effects of Very Low Nicotine Content Cigarettes (NCT05707871) | Bored Studies