RecruitingAccepts healthy volunteersEarly Phase 1
Cardiovascular Effects of Very Low Nicotine Content Cigarettes
Wake Forest University Health Sciences · NCT05707871
View Study & Apply (opens in a new tab)
Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.
Key facts
- Compensation
- Not posted. Ask the study team before screening.
- Who can join
- Ages 21+ · All sexes
- Healthy volunteers
- Accepted
- Study type
- Interventional · Early Phase 1
- Target enrollment
- 49
- US sites recruiting
- 1
- Study start
- April 4, 2023
- Record last updated
- August 28, 2026
Status re-checked against ClinicalTrials.gov within the last 12 hours.
What the study is about
The study is measuring Cardiovascular effects of very low nicotine content cigarettes on daily and non-daily smokers
Being studied: SPECTRUM cigarettes; usual brand of Cigarettes
Conditions: Tobacco Use
Eligibility criteria
Copied from the official record. The study team makes the final decision at screening.
Show full criteria
Inclusion Criteria
- Self-reported cigarette smoking at least once in the past 30 days
- ≥21 years old
- Willingness to smoke research cigarettes or usual brand cigarettes during lab visit.
- Ability to speak, comprehend, and read English sufficiently to complete study procedures
Exclusion Criteria
- Self-reported diagnosis of cardiovascular diseases like coronary artery disease, stroke, peripheral artery disease, cardiac arrhythmia, pulmonary embolism \& blood clots in legs and arm in the past 3 months
- Body temperature ≥ 100.4˙F
- Unstable health conditions interfering with electrocardiogram (ECG) measurements
- Self-reported diagnosis of hyperthyroidism or thyrotoxicosis
- Currently pregnant (as indicated by urine pregnancy test at the start of laboratory visit) or breastfeeding.
- Currently seeking treatment to quit smoking
Recruiting US locations
Wake Forest University Health Sciences
Winston-Salem, NC 27157
Site contact: Maria Anwar, MS · 802-922-3343 · manwar@wakehealth.edu
Study contacts (from the official record)
- Maria Anwar, MS · 802-922-3343 · manwar@wakehealth.edu
Similar studies in North Carolina
All heart & blood pressure studies in North Carolina →- RecruitingHealthy volunteers
Observational Pharmaco-Epidemiology Research & Analysis
Epividian
- Location
- Durham, NC
- Eligibility basics
- Ages 0 mo+
- RecruitingHealthy volunteers
A Usability Study of a Multi-channel ECG Monitoring Device
Wearlinq
- Location
- New London, NC
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
AI-Enabled Direct-from-ECG Ejection Fraction (EF) Severity Assessment Using COR ECG Wearable Monitor
Peerbridge Health, Inc
- Location
- Greensboro, NC + 7 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Clinical Trial of MK-7262 and Enlicitide in Participants With High Lipoprotein(a) (MK-7262-004)
Merck Sharp & Dohme LLC
- Location
- Durham, NC + 23 other US sites
- Eligibility basics
- Ages 18+