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CHAAMP (CHArlotte Advocate MGUS Project) Internal Pilot Study

Wake Forest University Health Sciences · with Atrium Health Levine Cancer Institute · NCT06644625

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 30+ · All sexes
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
1665
US sites recruiting
1
Study start
March 1, 2025
Record last updated
July 13, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The purpose of this study is to identify multiple myeloma in the precancerous MGUS stage in order to reduce the risk of delayed diagnosis of multiple myeloma, decrease morbidity related to multiple myeloma at progression, and improve long term outcomes.

Being studied: Blood draw for the laboratory assessment

Conditions: Multiple Myeloma; Multiple Myeloma Progression; Monoclonal Gammopathy of Undetermined Significance (MGUS); Smoldering Multiple Myeloma (SMM); Plasma Cell Disorders

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

SCREENING Inclusion Criteria

  • Age 30 years or older at the time of consent
  • Either:
  • Self-identify as Black and/or African American OR
  • First-degree relatives (parents, siblings, or children) of patients of any race or ethnicity diagnosed with a plasma cell disorder, including MGUS, smoldering multiple myeloma (SMM), multiple myeloma (MM), solitary plasmacytoma, plasma cell leukemia, AL amyloidosis, POEMS syndrome, and Waldenström's Macroglobulinemia
  • Capable and willing to provide informed consent. NOTE: HIPAA (Health Insurance Portability and Accountability Act) authorization for the release of personal health information may be included in the informed consent or obtained separately
  • Reside in Charlotte, NC, or the surrounding area, based on self-report

SCREENING Exclusion Criteria

  • Self-reported history of MGUS, SMM, MM, AL amyloidosis, plasma cell leukemia, solitary plasmacytoma, Waldenstrom Macroglobulinemia, and POEMS.

LONGITUDINAL Inclusion Criteria

  • Test positive for monoclonal gammopathy during screening portion of the study
  • Consent to the longitudinal portion of the study

LONGITUDINAL Exclusion Criteria

  • The participant previously underwent diagnostic work up as part of CHAAMP Internal Pilot that did not result in a diagnosis of MGUS, Smoldering Multiple Myeloma or other non-plasma cell disorder.

Recruiting US locations

  • Atrium Health Levine Cancer

    Charlotte, NC 28204

    Site contact: Margarita Dzhanumova · 704-754-3768 · margarita.dzhanumova@atriumhealth.org

Study contacts (from the official record)

  • Margarita Dzhanumova · 704-754-3768 · margarita.dzhanumova@atriumhealth.org
CHAAMP (CHArlotte Advocate MGUS Project) Internal Pilot Study (NCT06644625) | Bored Studies