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Duke APOL1 Research Biorepository

Duke University · NCT04160507

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18+ · All sexes
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
200
US sites recruiting
1
Study start
December 13, 2019
Record last updated
August 27, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The Duke ApoL1 Nephropathy Biorepository aims to address needs within non-diabetic kidney failure research by utilizing existing and, when necessary, developing new infrastructure to support the consent of patients and the collection of dedicated samples for ApoL1 Nephropathy biorepository.

The mutations in ApoL1 gene that are strongly associated with kidney disease are only present in individuals of recent African ancestry (i.e., black people). Caucasians do not have these ApoL1 mutations nor the associated kidney disease. Therefore, majority of subjects recruited for this study will be self-identified African Americans, Afro-Caribbean and other black individual. Study subjects will include individuals with end stage kidney disease and those without any clinical evidence of kidney disease.

Additionally, healthy black adults with no known history of kidney disease will be recruited as controls in this study because they are the only group that can fill this role.

Being studied: Biorepository

Conditions: End Stage Kidney Disease

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Majority of subjects recruited for this study will be self-identified African Americans, Afro-Caribbean and other black individuals. Study subjects will include individuals at various stages of kidney disease and those without any clinical evidence of kidney disease.
  • Healthy black adults, age 50 and older with no known history of kidney disease will be recruited as controls

Exclusion Criteria

  • Black adult cases with diabetic nephropathy
  • Healthy controls with kidney disease

Recruiting US locations

  • Duke University Medical Center

    Durham, NC 27705

    Site contact: Leshon A Matthews, BAS · 9196600731 · leshon.matthews@duke.edu

Study contacts (from the official record)

  • Opeyemi Olabisi, MD/PHD · 919-660-6987 · opeyemi.olabisi@duke.edu
  • Leshon A Matthews, BAS · 9196600731 · leshon.matthews@duke.edu
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Duke APOL1 Research Biorepository (NCT04160507) | Bored Studies