Evaluation of Efficacy, Safety, and Tolerability of Povetacicept in Participants With Primary Membranous Nephropathy (pMN)
Vertex Pharmaceuticals Incorporated · with Zai Lab (Shanghai) Co., Ltd. (for China only) · NCT07204275
Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.
Key facts
- Compensation
- Not posted. Ask the study team before screening.
- Who can join
- Ages 18–75 · All sexes
- Healthy volunteers
- Not accepted (a condition is required)
- Study type
- Interventional · Phase 2, Phase 3
- Target enrollment
- 176
- US sites recruiting
- 27
- Study start
- September 30, 2025
- Record last updated
- September 18, 2026
Status re-checked against ClinicalTrials.gov within the last 12 hours.
What the study is about
The purpose of this study is to evaluate the efficacy, safety, and tolerability of povetacicept in participants with primary membranous nephropathy (pMN).
Being studied: Povetacicept; Tacrolimus
Conditions: Primary Membranous Nephropathy
Eligibility criteria
Copied from the official record. The study team makes the final decision at screening.
Show full criteria
Key Inclusion Criteria
- Diagnosed with pMN with confirmatory historical biopsy. If no historical biopsy was performed that confirmed pMN, a biopsy can be performed during Screening to confirm eligibility
Key Exclusion Criteria
- Hypersensitivity to investigational medicinal product or to any of its excipients
Other protocol defined Inclusion/Exclusion criteria will apply
Recruiting US locations
Renal Associates
Montgomery, AL 36117
Southwest Kidney Institute, PLC (SKI) - Surprise
Surprise, AZ 85374
Academic Medical Research Institute (AMRI)
Los Angeles, CA 90022
Kaiser Permanente Sacramento Medical Center
Sacramento, CA 95825
Valiance Clinical Research - Internal Medicine
Tarzana, CA 91356
Western Nephrology & Metabolic Bone Disease PC
Arvada, CO 80002
Bioresearch Partner
Miami, FL 33127
CTR Oakwater, LLC
Orlando, FL 32806
Clinical Site Partners, LLC - Orlando
Winter Park, FL 32789
DaVita Clinical Research Columbus
Columbus, GA 31904
Georgia Nephrology
Lawrenceville, GA 30046
CARE Institute-Boise Kidney
Boise, ID 83706
NANI Research
Hinsdale, IL 60521
Nephrology Associates of Northern Illinois and Indiana (NANI) - Indianapolis South
Indianapolis, IN 46227
Northwest Louisiana Nephrology, LLC - Shreveport
Shreveport, LA 71101
DaVita Clinical Research Edina
Edina, MN 55435
St. Clair Nephrology Research
Roseville, MO 48066
Kidney Specialists of Southern Nevada
Las Vegas, NV 89107
NYU Medical Center
New York, NY 10016-9196
Carolina Nephrology Greenville
Greenville, SC 29605
Carolina Nephrology, PA
Spartanburg, SC 29306
El Paso Kidney Specialists
El Paso, TX 79902
Provecta Research Network
Houston, TX 77027
DaVita Clinical Research Houston
Houston, TX 77054
Davita Clinical Research San Antonio
San Antonio, TX 78251
Utah Kidney Research
Salt Lake City, UT 84115
Milwaukee Neprologists, SC
Wauwatosa, WI 53226
Study contacts (from the official record)
- Medical Information · 001-617-341-6777 · medicalinfo@vrtx.com