Skip to content
Bored Studies
RecruitingAccepts healthy volunteers

Evaluation of the Pathobiology of CALR-mutated MPN Cells

Wake Forest University Health Sciences · with Atrium Health Levine Cancer Institute, Brookdale University Hospital Medical Center · NCT06480591

View Study & Apply (opens in a new tab)

Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18+ · All sexes
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
35
US sites recruiting
2
Study start
January 21, 2025
Record last updated
July 13, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The purpose of this study is to understand why there is a greater risk of thrombosis in patients who have the JAK2 mutation as compared to those with CALR mutations.

Being studied: Blood Draw

Conditions: Myeloproliferative Neoplasm

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Written (or electronic) informed consent and HIPAA authorization for release of personal health information by participant or his/her legally authorized representative (LAR).
  • Age ≥ 18 years at the time of enrollment
  • Diagnosis of myeloproliferative neoplasm (MPN) according to 2022 World Health Organization classification of MDS/MPNs
  • CALR-positive genetic mutation

Exclusion Criteria

  • Diagnosis of MPN with JAK2 V617F mutation

Recruiting US locations

  • Atrium Health Levine Cancer

    Charlotte, NC 28204

    Site contact: Courtney Schepel · (980) 292-0817 · Courtney.Schepel@atriumhealth.org

  • Wake Forest Baptist Comprehensive Cancer Center

    Winston-Salem, NC 27157

    Site contact: Ruben Mesa, MD · 336-716-4618 · ruben.mesa@atriumhealth.org

Study contacts (from the official record)

  • Courtney Schepel · (980) 292-0817 · Courtney.Schepel@atriumhealth.org
Evaluation of the Pathobiology of CALR-mutated MPN Cells (NCT06480591) | Bored Studies