Gauging Outcomes of Total Milk Ingestion on Lipid and gControl
University of California, San Francisco · NCT07087184
Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.
Key facts
- Compensation
- Not posted. Ask the study team before screening.
- Who can join
- Ages 18+ · All sexes
- Healthy volunteers
- Accepted
- Study type
- Interventional · Not applicable
- Target enrollment
- 110
- US sites recruiting
- 1
- Study start
- July 24, 2025
- Record last updated
- October 2, 2026
Status re-checked against ClinicalTrials.gov within the last 12 hours.
What the study is about
Atherosclerotic cardiovascular disease remains the leading cause of death for adults in the United States. The cardiovascular impact of milk consumption remains a matter of long-standing scientific debate. Current guidelines for Americans recommend three daily servings of fat-free or low-fat (1%) dairy over full-fat options due to concerns that saturated fat may increase cardiovascular risk. Yet, the literature does not consistently support non-fat dairy as superior to high-fat dairy for reducing cardiometabolic risk. Identifying the comparative health benefits of non-fat versus high-fat dairy milk would be immediately applicable to patients who seek cardiovascular care. In this randomized, case-crossover trial, the investigators seek to efficiently assess the association between high-fat versus non-fat dairy milk consumption and insulin resistance. Utilizing the Eureka Platform, participants will be randomized to limit their liquid milk consumption to whole milk followed by skim milk (or vice versa), measuring the effect of milk fat content on glycemic index and lipid profile.
Being studied: Whole Milk-Skim Milk; Skim Milk-Whole Milk
Conditions: Heart Diseases; Cardiovascular Disease
Eligibility criteria
Copied from the official record. The study team makes the final decision at screening.
Show full criteria
Inclusion Criteria
- Are age ≥18 years
- Have a smartphone
- Are able to use the Eureka mobile application
- Consume, on average, at least one cup of dairy milk daily, at least 5 days per week
Exclusion Criteria
- Non-English speaker
- Are lactose intolerant
- History of myocardial infarction
- History of type I or type II diabetes
- Familial hypercholesterolemia
- Plan to change treatment for cholesterol
- Are pregnant or plan on getting pregnant
- Unable to read or sign to provide informed consent
Recruiting US locations
UCSF Medical Center at Parnassus
San Francisco, CA 94143
Site contact: Gregory M Marcus, MD, MAS · 415-476-5706 · greg.marcus@ucsf.edu
Study contacts (from the official record)
- Gregory M Marcus, MD, MAS · 415-476-5706 · greg.marcus@ucsf.edu
- Bella Peña · 415-502-3053 · bella.pena@ucsf.edu
Similar studies in California
All diabetes studies in California →- RecruitingHealthy volunteersPhase 1Overnight stay mentioned
A Study to Investigate the Relative Bioavailability and Safety of Different Oral Formulations of Elecoglipron in Healthy Participants
AstraZeneca
- Location
- Glendale, CA + 1 other US site
- Eligibility basics
- Ages 18–55
- RecruitingHealthy volunteersPhase 1
A Study to Evaluate Safety, Tolerability and Pharmacokinetics of Orally Administered TIX100 in Healthy Subjects
TIXiMED, Inc.
- Location
- Chula Vista, CA
- Eligibility basics
- Ages 18–70
- RecruitingHealthy volunteersPhase 1
Safety and Drug Concentrations of REGN20934 in Adults With Overweight or Obesity
Regeneron Pharmaceuticals
- Location
- Glendale, CA
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 1
A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4248 in Healthy Participants and Participants With Chronic Kidney Disease and Type 2 Diabetes and to Assess Home Measurements of…
AstraZeneca
- Location
- Glendale, CA + 3 other US sites
- Eligibility basics
- Ages 18–75