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Gauging Outcomes of Total Milk Ingestion on Lipid and gControl

University of California, San Francisco · NCT07087184

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18+ · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
110
US sites recruiting
1
Study start
July 24, 2025
Record last updated
October 2, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

Atherosclerotic cardiovascular disease remains the leading cause of death for adults in the United States. The cardiovascular impact of milk consumption remains a matter of long-standing scientific debate. Current guidelines for Americans recommend three daily servings of fat-free or low-fat (1%) dairy over full-fat options due to concerns that saturated fat may increase cardiovascular risk. Yet, the literature does not consistently support non-fat dairy as superior to high-fat dairy for reducing cardiometabolic risk. Identifying the comparative health benefits of non-fat versus high-fat dairy milk would be immediately applicable to patients who seek cardiovascular care. In this randomized, case-crossover trial, the investigators seek to efficiently assess the association between high-fat versus non-fat dairy milk consumption and insulin resistance. Utilizing the Eureka Platform, participants will be randomized to limit their liquid milk consumption to whole milk followed by skim milk (or vice versa), measuring the effect of milk fat content on glycemic index and lipid profile.

Being studied: Whole Milk-Skim Milk; Skim Milk-Whole Milk

Conditions: Heart Diseases; Cardiovascular Disease

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Are age ≥18 years
  • Have a smartphone
  • Are able to use the Eureka mobile application
  • Consume, on average, at least one cup of dairy milk daily, at least 5 days per week

Exclusion Criteria

  • Non-English speaker
  • Are lactose intolerant
  • History of myocardial infarction
  • History of type I or type II diabetes
  • Familial hypercholesterolemia
  • Plan to change treatment for cholesterol
  • Are pregnant or plan on getting pregnant
  • Unable to read or sign to provide informed consent

Recruiting US locations

  • UCSF Medical Center at Parnassus

    San Francisco, CA 94143

    Site contact: Gregory M Marcus, MD, MAS · 415-476-5706 · greg.marcus@ucsf.edu

Study contacts (from the official record)

  • Gregory M Marcus, MD, MAS · 415-476-5706 · greg.marcus@ucsf.edu
  • Bella Peña · 415-502-3053 · bella.pena@ucsf.edu
All diabetes studies in California →
Gauging Outcomes of Total Milk Ingestion on Lipid and gControl (NCT07087184) | Bored Studies