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Low Energy Availability and Hypertension in Division I HBCU Athletes

North Carolina Agriculture & Technical State University · with National Heart, Lung, and Blood Institute (NHLBI) · NCT07583940

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–26 · All sexes
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
150
US sites recruiting
1
Study start
January 6, 2026
Record last updated
May 13, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

Low energy availability (LEA) occurs when the body does not get enough calories to support both daily life and exercise. This can happen when athletes train hard but do not eat enough to match their energy needs. In both 2012 and 2023, the International Olympic Committee on Sports Nutrition recognized LEA as an important factor that can increase the risk of cardiometabolic disease (CMD), which includes conditions like high blood pressure, diabetes, and heart disease. LEA can affect many systems in the body. It may disrupt hormones (such as menstrual cycles), cause changes in blood sugar and cholesterol levels, weaken bones, impair digestion, and negatively impact mental health. Over time, these changes may be linked to chronic inflammation, which plays a key role in the development of disease. Maintaining proper energy balance can be especially challenging for athletes because they often train at levels well above general health recommendations. As a result, even highly fit athletes may unintentionally remain in a calorie deficit. Our recent pilot research found a significant relationship between LEA and high blood pressure in Black Division I collegiate athletes. This is important because this group has historically been understudied and may face a higher risk of serious heart-related events, including sudden cardiac death. Despite assumptions that collegiate athletes are uniformly healthy, there is a need to better understand hidden health risks in this population. Our research aims to improve how we identify and monitor early signs of cardiometabolic disease by examining markers such as inflammation, blood sugar, and cholesterol levels. These insights will help healthcare providers, athletes, and families make more informed decisions about nutrition, training, and long-term health. Ultimately, this work seeks to develop practical, evidence-based strategies to protect athlete health and reduce the risk of serious cardiovascular outcomes.

Conditions: Vascular Stiffness; Hypertension (HTN); Nutritional Deficiency Related Cardiovascular Risk in Athletes

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

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Inclusion Criteria

Age: 18-25yrs Sex: Male and Female Training Status/Experience: HBCU Division I collegiate athletes with >3yrs of previous competitive experience

Exclusion Criteria

  • Persons who self-report any known disease, or unknown issue precluding collegiate competitive participation: Excluded
  • Those who have any orthopedic injuries, concussions, or conditions which would preclude safe testing: Excluded
  • Individuals who are not yet adults \<18yrs (e.g.: infants, children, teenagers):

Excluded

  • Persons who have a pacemaker: Excluded
  • Persons who are pregnant: Excluded

Recruiting US locations

  • North Carolina Agricultural & Technical State University

    Greensboro, NC 27411

    Site contact: Troy M Purdom, PhD · 3362853552 · tpurdom@ncat.edu

Study contacts (from the official record)

  • Troy M Purdom, PhD · 13362853552 · tpurdom@ncat.edu
  • Catherine Bush, PhD · 3363347712 · cmbush@ncat.edu
Low Energy Availability and Hypertension in Division I HBCU Athletes (NCT07583940) | Bored Studies