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Pain in Juvenile Arthritis

Washington University School of Medicine · NCT07217782

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 9–17 · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
140
US sites recruiting
1
Study start
September 15, 2025
Record last updated
July 14, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

Juvenile idiopathic arthritis (JIA) is the most common rheumatologic disease in children. The main symptoms of JIA, which are often the primary focus of treatment, include joint swelling, stiffness, and tenderness. Additional symptoms can include malaise, fatigue, and pain. However, the exact mechanisms contributing to pain are not yet fully understood. Participants will complete a 2.5-hours study session.

In the study session, psychophysical assessments of thermal and pressure stimuli will be performed. In addition, demographic, social, pubertal maturation, and behavioral and psychological factors will be collected via questionnaires. A saliva sample and/or blood draw may occur for the analysis of various immune factors and sex hormones. If a joint aspiration is done as part of their standard of care, we will request a sample of the synovial fluid for analyses of immune, hormonal and/or genetic factors. Participants will have the option to participate in additional optional follow-up study visits (every 3 months, up to 1 year) and to complete monthly surveys asking about their juvenile arthritis.

Being studied: Pressure pain thresholds (measured in kilopascal); Cold pain tolerance (duration in seconds)

Conditions: Juvenile Idiopathic Arthritis

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Age between 9-17
  • Males and females
  • English speakers
  • Able to complete surveys and understand study instructions
  • Juvenile arthritis group: diagnosed or suspected of juvenile arthritis
  • Control group: healthy

Exclusion Criteria

  • Pregnancy or breastfeeding
  • (Control Group) Diagnosed with a chronic pain condition
  • (Control Group) Diagnosed with psychiatric condition including ADHD, anxiety, depression, etc.

Recruiting US locations

  • Washington University School of Medicine

    St Louis, MO 63017

    Site contact: Hadas Nahman-Averbuch, PhD · 314-273-6194 · painlab@wustl.edu

Study contacts (from the official record)

  • Alana McMichael, MA · 314-273-6194 · painlab@wustl.edu
All arthritis studies in Missouri →
Pain in Juvenile Arthritis (NCT07217782) | Bored Studies