Platform Study to Evaluate the Efficacy and Safety of Investigational Compound(s) in Patients With Moderate to Severe Atopic Dermatitis
Novartis Pharmaceuticals · NCT06947993
Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.
Key facts
- Compensation
- Not posted. Ask the study team before screening.
- Who can join
- Ages 18–100 · All sexes
- Healthy volunteers
- Not accepted (a condition is required)
- Study type
- Interventional · Phase 2
- Target enrollment
- 224
- US sites recruiting
- 24
- Study start
- May 16, 2025
- Record last updated
- September 28, 2026
Status re-checked against ClinicalTrials.gov within the last 12 hours.
What the study is about
This trial is designed to evaluate multiple compounds in participants with moderate to severe atopic dermatitis (AD).
Being studied: GHZ339; Placebo
Conditions: Atopic Dermatitis
Eligibility criteria
Copied from the official record. The study team makes the final decision at screening.
Show full criteria
Key Inclusion Criteria of the master protocol:
- Able and willing to sign the informed consent (IC)
- Patients with a diagnosis of AD and onset of disease for at least 1 year
- Moderate to severe AD
Key Exclusion Criteria of the master protocol:
- Participants with a clinically significant medical condition or infectious disease (specified in sub-protocol)
- Participants with clinically significant abnormal hematology, clinical chemistry, or urine test results or clinically significant abnormal ECG
- Participant with any other active inflammatory skin disease
- Participants with any chronic, uncontrolled medical condition, which would put the participant at increased risk during the study (e.g., uncontrolled: diabetes, hypertension)
- Participants with any clinically unstable disease states that would likely require systemic corticosteroids (e.g., uncontrolled asthma)
Additional inclusion and exclusion criteria may apply depending on the intervention specific requirements
Recruiting US locations
Novartis Investigative Site
Birmingham, AL 35233
Novartis Investigative Site
Birmingham, AL 35244
Novartis Investigative Site
Fort Smith, AR 72916
Novartis Investigative Site
Fountain Valley, CA 92708
Novartis Investigative Site
Los Angeles, CA 90056
Novartis Investigative Site
Sacramento, CA 95815
Novartis Investigative Site
Santa Ana, CA 92701
Novartis Investigative Site
Santa Monica, CA 90404
Novartis Investigative Site
Washington D.C., DC 20060
Novartis Investigative Site
Miami, FL 33144
Novartis Investigative Site
St. Petersburg, FL 33705
Novartis Investigative Site
Atlanta, GA 30342
Novartis Investigative Site
Macon, GA 31217
Novartis Investigative Site
Louisville, KY 40241
Novartis Investigative Site
Brighton, MA 02135
Novartis Investigative Site
Troy, MI 48084
Novartis Investigative Site
Saint Joseph, MO 64506
Novartis Investigative Site
Portsmouth, NH 03801
Novartis Investigative Site
Brooklyn, NY 11203
Novartis Investigative Site
Arlington, TX 76011
Novartis Investigative Site
Cypress, TX 77433
Novartis Investigative Site
Dallas, TX 75235-9069
Novartis Investigative Site
Houston, TX 77030
Novartis Investigative Site
San Antonio, TX 78218
Study contacts (from the official record)
- Novartis Pharmaceuticals · 1-888-669-6682 · novartis.email@novartis.com
- Novartis Pharmaceuticals · +41613241111
Similar studies in Alabama
All dermatology studies in Alabama →- RecruitingHealthy volunteersPhase 1
First-in-Human Trial to Assess REGN20423 in Healthy Adult Participants and Adult Participants With Atopic Dermatitis
Regeneron Pharmaceuticals
- Location
- Birmingham, AL + 5 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 2/Phase 3
Phase 2/3 Efficacy and Safety of PP405 in Adult Males
Pelage Pharmaceuticals, Inc.
- Location
- Birmingham, AL + 26 other US sites
- Eligibility basics
- Ages 18–55 · Men only
- RecruitingPhase 3
A Study of 2 Doses of Ritlecitinib in People 12 Years of Age and Older With Alopecia Areata
Pfizer
- Location
- Birmingham, AL + 28 other US sites
- Eligibility basics
- Ages 12+
- RecruitingPhase 3
A Long-term Study of the Medicine Called Abrocitinib in Children Aged 2 Years and Older With Moderate to Severe Eczema
Pfizer
- Location
- Birmingham, AL + 6 other US sites
- Eligibility basics
- Ages 2–11