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Postnatal Exercise to Activate Baby's Brown Fat

Joslin Diabetes Center · with University of Oklahoma, National Institutes of Health (NIH) · NCT07467694

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18–45 · Women only
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
200
US sites recruiting
2
Study start
December 1, 2025
Record last updated
March 12, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

The purpose of this study is to learn how exercise and physical activity during pregnancy and after pregnancy may affect the composition of breastmilk. Certain changes in breast milk after exercise may have an impact on how infants use energy. Understanding this process may improve public health recommendations for exercise during and after pregnancy. This study can help investigators learn more about how maternal exercise patterns may affect body growth and obesity risk in infants who are breastfed. This research may help identify how different factors can influence healthy weight and early development in infants.

Being studied: Active group

Conditions: Childhood Obesity Prevention; Childhood Obesity; Physical Activity; Lactation; Breastfeeding; Pregnancy; Exercise

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • 18-45 y of age at the time of enrollment
  • Pre-gravid or first trimester BMI 18.5 -40 kg/m2
  • Uncomplicated singleton pregnancy
  • Intention to exclusively breastfeed for >3 months and, if parity >1, that they successfully breastfed a previous pregnancy
  • Term pregnancy (gestational age 37 to \<42 weeks)
  • Infant with birth weight >10th percentile of weight for gestational age

Exclusion Criteria

  • Any obstetric contra-indication to exercise at 1 month
  • Diagnosis of uncontrolled (HbA1c >7%) type 1 or type 2 diabetes, or gestational diabetes managed with insulin
  • Intrauterine growth restriction
  • Pre-eclampsia or other pregnancy complications
  • Alcohol, cannabis or tobacco use
  • Known congenital metabolic, endocrine disease, or congenital illness affecting infant feeding/growth
  • Major fetal anomalies
  • Musculoskeletal issues that would make exercise difficult

Recruiting US locations

  • Joslin Diabetes Center

    Boston, MA 02215

    Site contact: Elvira Isganaitis, MD · elvira.isganaitis@joslin.harvard.edu

  • Oklahoma University College of Medicine

    Oklahoma City, OK 73104

    Site contact: Katy Duncan · katy-duncan@ou.edu

Study contacts (from the official record)

  • Elvira M Isganaitis, MD, MPH · 617-309-4554 · elvira.isganaitis@joslin.harvard.edu
  • Study Coordinator · 857-289-3455 · PeaBaBy@joslin.harvard.edu
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Postnatal Exercise to Activate Baby's Brown Fat (NCT07467694) | Bored Studies