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Prostate Cancer Screening for People at Genetic Risk for Aggressive Disease, PATROL Study

University of Washington · with National Cancer Institute (NCI), Canary Foundation · NCT04472338

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 40+ · Men only
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
450
US sites recruiting
7
Study start
May 21, 2020
Record last updated
May 15, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

This study investigates ways to detect prostate cancer earlier in people at genetic risk for disease that forms, grows, or spreads quickly (aggressive). Studying samples of blood, urine, and/or tissue in the laboratory may help doctors further understand the genetics of prostate cancer and help identify ways to detect cancer earlier, thereby improving treatment and methods of early detection in the future.

Being studied: Biospecimen Collection; Laboratory Biomarker Analysis; Quality-of-Life Assessment; Questionnaire Administration

Conditions: Prostate Carcinoma

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • People with prostates ≥40 years of age
  • Documented germline pathogenic variant in known or suspected genes associated with prostate cancer risk.

Exclusion Criteria

  • Prior diagnosis of prostate cancer
  • Medical contraindication to any of the study procedures (e.g., prostate biopsy)
  • For all cancer types except non-melanoma skin cancer, any cancer treatment with curative intent within the past 12 months (e.g., surgery, radiation, chemotherapy, immunotherapy)
  • Prior or concurrent participation in an interventional clinical trial aimed at preventing cancer for people with germline variants associated with increased prostate cancer risk
  • Unable to provide written informed consent
  • Unable or unwilling to complete clinical care and study procedures as indicated by the study protocol.

Recruiting US locations

  • City of Hope

    Duarte, CA 91010

    Site contact: Joanne Jeter, MD

  • University of California, San Francisco

    San Francisco, CA 94143

    Site contact: Ada Sanchez · ada.sanchez@ucsf.edu

  • Northwestern

    Chicago, IL 60611

    Site contact: Sophia Kallas · Sophia.kallas@northwestern.edu

  • Massachusetts General Hospital

    Boston, MA 02114

    Site contact: Keyan Salari, MD, PhD

  • OHSU Knight Cancer Institute

    Portland, OR 97239

    Site contact: Alexandra Sokolova, MD · 503-418-8150 · cedartrials@ohsu.edu

  • University of Pennsylvania/Abramson Cancer Center

    Philadelphia, PA 19104

    Site contact: Kara Maxwell, MD, PhD · 215-615-3004 · PATROL@pennmedicine.upenn.edu

  • Fred Hutch/University of Washington Cancer Consortium

    Seattle, WA 98109

    Site contact: Study Team Coordinator · 206-210-4040 · patrol@uw.edu

Study contacts (from the official record)

  • Study Team Coordinator · 206-210-4040 · patrol@uw.edu
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Prostate Cancer Screening for People at Genetic Risk for… (NCT04472338) | Bored Studies