Skip to content
Bored Studies
RecruitingAccepts healthy volunteersPhase 4

The Role of Neutrophils in the Age-driven Decline in Anti-pneumococcal Vaccine Responses

State University of New York at Buffalo · with National Institute on Aging (NIA) · NCT06128915

View Study & Apply (opens in a new tab)

Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 21+ · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Phase 4
Target enrollment
60
US sites recruiting
1
Study start
January 8, 2024
Record last updated
April 3, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

This study focuses on the role of neutrophils in shaping the adaptive immune response to the anti-pneumococcal vaccine Prevnar-13 in young and elderly adults.

Being studied: vaccine

Conditions: Aging

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Both sexes
  • Have not been vaccinated with any licensed or experimental pneumococcal vaccine
  • Ages 21-40; and ≥65. Individuals >60 years old will also be recruited in case we find no unvaccinated people ≥65 years old
  • Free of acute infections within the last 2 weeks
  • Did not take any anti-inflammatory medicine in the last week
  • Did not ingest alcohol in the last 24 hours
  • Ability and willingness to provide consent

Exclusion Criteria

  • Previous vaccination with any licensed or experimental pneumococcal vaccine
  • Known hypersensitivity to vaccination and vaccine components
  • Immune deficiency
  • Use of immune-modulating or suppressive drugs
  • Malignancies within the last 2 years
  • Known hematological, rheumatic and inflammatory diseases
  • Known chronic infections
  • Poorly controlled chronic cardiovascular and metabolic conditions
  • Pregnancy
  • Dementia

Recruiting US locations

  • University at Buffalo

    Buffalo, NY 14203

    Site contact: Catherine Wrona

Study contacts (from the official record)

  • Elsa Bou Ghanem, PhD · 7168292422 · elsaboug@buffalo.edu
All vaccine studies in New York →
The Role of Neutrophils in the Age-driven Decline in… (NCT06128915) | Bored Studies