Location · Lake Forest, CA
Clinical trials in Lake Forest, CA
17 recruiting studies have a site in Lake Forest, and 7 of them accept healthy volunteers.
17 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteersPhase 1Overnight stay mentioned
A Study to Learn How the Body Processes the Study Medicine PF-07328948 in People With Reduced Kidney Function
Pfizer
- Location
- Lake Forest, CA + 3 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingHealthy volunteersPhase 1/Phase 2
First-in-human Study of the Safety, Tolerability, Pharmacokinetics, and Food Effect of ACCG-2671
Aconcagua Bio, Inc. a wholly owned subsidiary of Structure Therapeutics
- Location
- Lake Forest, CA + 2 other US sites
- Eligibility basics
- Ages 25–75
- RecruitingHealthy volunteersPhase 1
A Study to Evaluate the Pharmacokinetics (PK) and Safety of a Single Dose of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Normal Hepatic Function and Participants With Hepatic Impairment
Insmed Incorporated
- Location
- Lake Forest, CA + 3 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingHealthy volunteersPhase 1
A Trial Evaluating AMG 127 in Healthy Participants and Participants With Type 2 Diabetes Mellitus
Amgen
- Location
- Lake Forest, CA + 1 other US site
- Eligibility basics
- Ages 18–75
- RecruitingHealthy volunteersPhase 1
A Study to Learn How the Body Processes the Study Medicine PF-07328948 in People With and Without Reduced Liver Function
Pfizer
- Location
- Lake Forest, CA + 2 other US sites
- Eligibility basics
- Ages 18–74
- RecruitingHealthy volunteersPhase 1
A Study to Learn About a Vaccine Against E Coli in Healthy Adults
Pfizer
- Location
- Lake Forest, CA + 9 other US sites
- Eligibility basics
- Ages 18–64
- RecruitingHealthy volunteersPhase 3
A Study to Assess the Safety, Tolerability, and Immunogenicity of 3 Lots of a Multivalent Pneumococcal Conjugate Vaccine Administered to Adults
Pfizer
- Location
- Lake Forest, CA + 36 other US sites
- Eligibility basics
- Ages 18–49
- RecruitingPhase 3
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes
Hoffmann-La Roche
- Location
- Lake Forest, CA + 44 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity
Amgen
- Location
- Lake Forest, CA + 136 other US sites
- Eligibility basics
- Ages 45–99
- RecruitingPhase 3
A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)
Eli Lilly and Company
- Location
- Lake Forest, CA + 136 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study to Evaluate ALN-AGT01 RVR in Adult Patients With Mild to Moderate Hypertension Pretreated With Zilebesiran
Alnylam Pharmaceuticals
- Location
- Lake Forest, CA
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
A Study of Orforglipron in Participants With Overweight at Risk of Development of Obesity-Related Complications or Progression to Class 1 Obesity
Eli Lilly and Company
- Location
- Lake Forest, CA + 68 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
A Phase 1 Study of VK3019 in Overweight and Obese Adults Without Comorbidities
Viking Therapeutics, Inc.
- Location
- Lake Forest, CA
- Eligibility basics
- Ages 18–60
- RecruitingPhase 1
A Study to Assess the Safety, Tolerability, and Pharmacokinetics of GIGA-2339 in Participants With Chronic Hepatitis B Virus Infection
GigaGen, Inc.
- Location
- Lake Forest, CA + 10 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
A Phase 1 Study of VK2735 in Obese Adults Without Comorbidities
Viking Therapeutics, Inc.
- Location
- Lake Forest, CA + 1 other US site
- Eligibility basics
- Ages 18–60
- RecruitingPhase 2
To Evaluate the Safety and Efficacy of MANP in Subjects With Difficult to Control/ Resistant Hypertension
E-Star BioTech, LLC
- Location
- Lake Forest, CA + 21 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 1
A Study to Learn How Different Amounts of the Study Medicine Called PF-08642534 Are Tolerated and Act in the Body of People Who Have Obesity
Pfizer
- Location
- Lake Forest, CA
- Eligibility basics
- Ages 18–70