Location · Chicago, IL
Clinical trials in Chicago, IL
738 recruiting studies have a site in the Chicago area, and 232 of them accept healthy volunteers. The area includes Evanston, Oak Brook, Oak Lawn, Park Ridge, Skokie, Maywood and nearby cities.
738 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteers
J-RISE: Relevant Implementation Strategies to Eliminate the Social and Structural Barriers to HIV Services Among Justice-involved Black Men Who Have Sex With Men and Other Key Populations
University of Chicago
- Location
- Chicago, IL
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 1/Phase 2
Study to Assess Safety and Immunogenicity of an Egg-based H5N8 Influenza Vaccine at Multiple Dose Levels Adjuvanted With Matrix-M in Healthy Participants 18 Years of Age and Above.
Sanofi
- Location
- Tempe, AZ + 15 other US sites
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 1
A Clinical Trial Investigating the Safety and Biological Activity of the Antibody BNT351 in Adults Living Without and With HIV
BioNTech SE
- Location
- Chicago, IL + 3 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 1
A Study of the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of BCX17725
BioCryst Pharmaceuticals
- Location
- Palo Alto, CA + 4 other US sites
- Eligibility basics
- Ages 12–65
- RecruitingHealthy volunteersPhase 1
A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4248 in Healthy Participants and Participants With Chronic Kidney Disease and Type 2 Diabetes and to Assess Home Measurements of…
AstraZeneca
- Location
- Glendale, CA + 3 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingHealthy volunteersPhase 1
A Study of Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SR604 in Two Participants Groups (Part A: Healthy Participants, and Part B: Participants With Hemophilia A or Hemophilia B or Factor VII…
Equilibra Bioscience LLC
- Location
- Los Angeles, CA + 6 other US sites
- Eligibility basics
- Ages 18–60
- RecruitingHealthy volunteersEarly Phase 1
Sleep, Dreaming, and Virtual Reality for Mental Health
Northwestern University
- Location
- Evanston, IL + 1 other US site
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersEarly Phase 1
Effect of Neural Constraints on Movement in Stroke
Northwestern University
- Location
- Chicago, IL
- Eligibility basics
- Ages 18–80
- RecruitingHealthy volunteersPhase 1
Ivosidenib and Ruxolitinib in Patients With Advanced Myeloproliferative Neoplasms (MPNs) That Have an IDH1 Gene Mutation
University of Chicago
- Location
- Chicago, IL + 1 other US site
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersOvernight stay mentioned
End Diagnostic Overshadowing
Rush University Medical Center
- Location
- Chicago, IL
- Eligibility basics
- Ages 3–89
- RecruitingHealthy volunteersPhase 1/Phase 2
Aging and Task-specific Training to Reduce Falls
University of Illinois at Chicago
- Location
- Chicago, IL
- Eligibility basics
- Ages 60–90
- RecruitingHealthy volunteersEarly Phase 1
rhPSMA-73 PET-MRI Imaging for the Detection of Prostate Cancer Among Men Who Are Otherwise Candidates for Active Surveillance
Northwestern University
- Location
- Chicago, IL
- Eligibility basics
- Ages 18+ · Men only
- RecruitingHealthy volunteersPhase 1/Phase 2
Behavioral Economic Attributes of Recreation
Rush University Medical Center
- Location
- Chicago, IL
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 1
Study of KM-023 in Healthy Volunteers and Patients With Olmsted Syndrome.
Orvida Pharma (formerly Kamari Pharma)
- Location
- Chicago, IL
- Eligibility basics
- Ages 18–55
- RecruitingHealthy volunteersPhase 1/Phase 2
Dex +/- Caffeine Sedation in a Post-MRI Recovery in a Pediatric Population
University of Chicago
- Location
- Chicago, IL
- Eligibility basics
- Ages 3–12
- RecruitingHealthy volunteersEarly Phase 1
R01.Aim 2.Study 1: IsoReach
Shirley Ryan AbilityLab
- Location
- Chicago, IL
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
A Study to Determine the Effect of Access to Multiple Tobacco Flavor Options on Smoking Abstinence Among Primary Cigarette Smokers Using an Electronic Nicotine Delivery System
RAI Services Company
- Location
- Fort Lauderdale, FL + 4 other US sites
- Eligibility basics
- Ages 21–65
- RecruitingHealthy volunteers
Effect of a Dietary Supplement Versus Placebo on Serum PFAS Levels in Male Firefighters
Cambiotics ApS
- Location
- Chicago, IL
- Eligibility basics
- Ages 18+ · Men only
- RecruitingHealthy volunteers
BoxX-NoAF Clinical Trial
AtriCure, Inc.
- Location
- Scottsdale, AZ + 30 other US sites
- Eligibility basics
- Ages 65+
- RecruitingHealthy volunteers
Observational Study of Decentralized Urine Optical Interaction Patterns Associated With Environmental Microplastic and Nanoplastic Exposure
Ecotera Health LLC
- Location
- Birmingham, AL + 50 other US sites
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events
Cleerly, Inc.
- Location
- Chandler, AZ + 121 other US sites
- Eligibility basics
- Ages 55+
- RecruitingHealthy volunteersPhase 3
A Study on the Efficacy of a Vaccine Against Influenza in Adults ≥65 Years of Age
GlaxoSmithKline
- Location
- Anniston, AL + 130 other US sites
- Eligibility basics
- Ages 65+
- RecruitingHealthy volunteersPhase 3
A Study to Learn About the Safety of an Expanded Pneumococcal Vaccine in Healthy Infants
Pfizer
- Location
- Estero, FL + 20 other US sites
- Eligibility basics
- Ages 1 mo–4 mo
- RecruitingHealthy volunteers
Falcon Real World Evidence Registry
Exact Sciences Corporation
- Location
- Evanston, IL + 1 other US site
- Eligibility basics
- Ages 50–80