Location · Springfield, IL
Clinical trials in Springfield, IL
35 recruiting studies have a site in Springfield, and 3 of them accept healthy volunteers.
35 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteers
Collection of Samples USOPTIVAL Study
Universal Diagnostics
- Location
- Springfield, IL + 3 other US sites
- Eligibility basics
- Ages 45–84
- RecruitingPhase 3
Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity of Surabgene Lomparvovec in Adult Participants With Neovascular Age-Related Macular…
AbbVie
- Location
- Springfield, IL + 54 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 3
Efficacy, Safety and Tolerability of Switching From Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA) to Maridebart Cafraglutide in Adults With Obesity or Overweight (MARITIME-SWITCH)
Amgen
- Location
- Springfield, IL + 51 other US sites
- Eligibility basics
- Ages 18–99
- Recruiting
A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With…
LivaNova
- Location
- Springfield, IL + 49 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 4
A Study of Vedolizumab in Adults With Ulcerative Colitis (UC) or Crohn's Disease (CD) in the Community Setting
Takeda
- Location
- Springfield, IL + 77 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 3
Study to Determine if BHV-1300 is Effective and Safe in Adults With Graves' Disease
Biohaven Therapeutics Ltd.
- Location
- Springfield, IL + 52 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 2/Phase 3
Surabgene Lomparvovec Administered in the Suprachoroidal Space in Adult Participants With Diabetic Retinopathy Without Center-Involved Diabetic Macular Edema
AbbVie
- Location
- Springfield, IL + 36 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Renal Pelvic Denervation Pilot Trial
Verve Medical, Inc
- Location
- Springfield, IL + 7 other US sites
- Eligibility basics
- Ages 21–80
- RecruitingPhase 3
Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease
Alnylam Pharmaceuticals
- Location
- Springfield, IL + 213 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart
Boehringer Ingelheim
- Location
- Springfield, IL + 78 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy
Regeneron Pharmaceuticals
- Location
- Springfield, IL + 144 other US sites
- Eligibility basics
- Ages 50–85
- RecruitingPhase 3
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes
Hoffmann-La Roche
- Location
- Springfield, IL + 44 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures
Xenon Pharmaceuticals Inc.
- Location
- Springfield, IL + 44 other US sites
- Eligibility basics
- Ages 12+
- RecruitingPhase 3
A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures (X-TOLE3)
Xenon Pharmaceuticals Inc.
- Location
- Springfield, IL + 14 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)
Bristol-Myers Squibb
- Location
- Springfield, IL + 22 other US sites
- Eligibility basics
- Ages 60–85
- RecruitingPhase 3
Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity
Amgen
- Location
- Springfield, IL + 136 other US sites
- Eligibility basics
- Ages 45–99
- RecruitingPhase 2
LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis
Eli Lilly and Company
- Location
- Springfield, IL + 38 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 2
A Study of Brenipatide (LY3537031) in Participants With Irritable Bowel Syndrome-Diarrhea (IBS-D)
Eli Lilly and Company
- Location
- Springfield, IL + 13 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2
A Study of Brenipatide (LY3537031) in Participants With Irritable Bowel Syndrome-Constipation (IBS-C)
Eli Lilly and Company
- Location
- Springfield, IL + 13 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2/Phase 3
A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002)
EyeBiotech Ltd.
- Location
- Springfield, IL + 66 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 2
RENAISSANCE 2: SPN-817 Phase 2, Double-Blind, Placebo-Controlled Study in Adults With Focal Onset Seizures
Supernus Pharmaceuticals, Inc.
- Location
- Springfield, IL + 36 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 3
A Study to Evaluate the Efficacy and Safety of Hetrombopag Olamine Tablets Vs Placebo in Patients With Chemotherapy-Induced Thrombocytopenia (ExCIT)
Jiangsu HengRui Medicine Co., Ltd.
- Location
- Springfield, IL + 7 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Efficacy of the COronary SInus Reducer in Patients With Refractory Angina II
Shockwave Medical, Inc.
- Location
- Springfield, IL + 66 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
Study of Targeted Therapies for the Treatment of Adult Participants With Moderate to Severe Crohn's Disease
AbbVie
- Location
- Springfield, IL + 53 other US sites
- Eligibility basics
- Ages 18–75