Location · Chapel Hill, NC
Clinical trials in Chapel Hill, NC
151 recruiting studies have a site in Chapel Hill, and 54 of them accept healthy volunteers.
151 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 3
Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction
Cytokinetics
- Location
- Chapel Hill, NC + 80 other US sites
- Eligibility basics
- Ages 18–85
- Recruiting
Onyx™ Liquid Embolic IDE Clinical Study
Medtronic Endovascular
- Location
- Chapel Hill, NC + 19 other US sites
- Eligibility basics
- Ages 22+
- RecruitingPhase 3
A Study to Investigate Efficacy and Safety of Teplizumab Compared With Placebo in Participants 1 to 25 Years of Age With Stage 3 Type 1 Diabetes
Sanofi
- Location
- Chapel Hill, NC + 33 other US sites
- Eligibility basics
- Ages 1–25
- RecruitingPhase 2
SAFety and Efficacy of Human Anti-thymocyte ImmunoGlobUlin SAB-142 ARresting Progression of Type 1 Diabetes
SAb Biotherapeutics, Inc.
- Location
- Chapel Hill, NC + 20 other US sites
- Eligibility basics
- Ages 5–40
- RecruitingPhase 3
A 52-Week Trial to Investigate the Efficacy and Safety of Delgocitinib Cream in Adult Participants With Lichen Sclerosus
LEO Pharma
- Location
- Chapel Hill, NC + 18 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study of JNJ-78934804 in Participants With Moderately to Severely Active Ulcerative Colitis
Janssen Research & Development, LLC
- Location
- Chapel Hill, NC + 23 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2/Phase 3
Alpelisib in Pediatric and Adult Patients With Lymphatic Malformations Associated With a PIK3CA Mutation.
Novartis Pharmaceuticals
- Location
- Chapel Hill, NC + 17 other US sites
- Eligibility basics
- Ages 0 mo–100
- RecruitingPhase 3
Rollover Study for Participants Previously Enrolled in Clinical Trials of Povorcitinib
Incyte Corporation
- Location
- Chapel Hill, NC + 73 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
EPIK-P4: A Phase II Single-arm Study to Assess the Efficacy, Safety and Pharmacokinetics of Alpelisib (BYL719) in Pediatric and Adult Patients With PIK3CA-related Overgrowth Spectrum (PROS)
Novartis Pharmaceuticals
- Location
- Chapel Hill, NC + 8 other US sites
- Eligibility basics
- Ages 2–100
- RecruitingPhase 3
TRITON-PN: A Study to Evaluate the Efficacy and Safety of Nucresiran in Patients With Hereditary Transthyretin Amyloidosis With Polyneuropathy
Alnylam Pharmaceuticals
- Location
- Chapel Hill, NC + 9 other US sites
- Eligibility basics
- Ages 18–85
- Recruiting
Zenith® Fenestrated+ Clinical Study
Cook Research Incorporated
- Location
- Chapel Hill, NC + 29 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus
Cabaletta Bio
- Location
- Chapel Hill, NC + 17 other US sites
- Eligibility basics
- Ages 12–65
- RecruitingPhase 2
ANCHOR Study: A Study to Assess the Safety and Efficacy of ABBV-CLS-628 in Adult Participants With Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Calico Life Sciences LLC
- Location
- Chapel Hill, NC + 33 other US sites
- Eligibility basics
- Ages 18–55
- RecruitingPhase 2
A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative Colitis
Spyre Therapeutics, Inc.
- Location
- Chapel Hill, NC + 25 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2
Trial Against INtractable Type 2 Diabetes (CAPTAIN-T2D)
Sparrow Pharmaceuticals
- Location
- Chapel Hill, NC + 60 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study of KT-621 Administered Orally to Adult Participants With Moderate to Severe Eosinophilic Asthma
Kymera Therapeutics, Inc.
- Location
- Chapel Hill, NC + 30 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 4
A Remotely Conducted Study to Assess Concentration of TREMFYA in Breast Milk of Lactating Women Who Are Receiving TREMFYA Therapeutically
Janssen Research & Development, LLC
- Location
- Chapel Hill, NC
- Eligibility basics
- Ages 18+ · Women only
- RecruitingPhase 2
A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease
Neuron23 Inc.
- Location
- Chapel Hill, NC + 43 other US sites
- Eligibility basics
- Ages 40–80
- RecruitingPhase 2
Phase 2, Efficacy and Safety Study of ACP-204 in Lewy Body Dementia Psychosis
ACADIA Pharmaceuticals Inc.
- Location
- Chapel Hill, NC + 27 other US sites
- Eligibility basics
- Ages 55–84
- RecruitingPhase 3
A Study of Dupilumab in Small Children With an Allergic Condition of the Esophagus (Food Pipe): Eosinophilic Esophagitis
Regeneron Pharmaceuticals
- Location
- Chapel Hill, NC + 12 other US sites
- Eligibility basics
- Ages 6 mo–6
- RecruitingPhase 2
A Study to Evaluate the Efficacy, Safety, Pharmacodynamics (PD), and Pharmacokinetics (PK) of Selnoflast in Reducing Vascular Inflammation in Participants With Atherosclerosis at Risk for Major Adverse Cardiac Events
Genentech, Inc.
- Location
- Chapel Hill, NC + 23 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study of Nipocalimab in Pregnancies at Risk for Severe Hemolytic Disease of the Fetus and Newborn (HDFN)
Janssen Research & Development, LLC
- Location
- Chapel Hill, NC + 19 other US sites
- Eligibility basics
- Ages 18–45 · Women only
- RecruitingPhase 3
A Study of Nipocalimab or Intravenous Immunoglobulin (IVIG) in Pregnancies At Risk of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT)
Janssen Research & Development, LLC
- Location
- Chapel Hill, NC + 11 other US sites
- Eligibility basics
- Ages 18–45 · Women only
- RecruitingPhase 2/Phase 3
A Study of Icotrokinra in Participants With Moderately to Severely Active Crohn's Disease
Janssen Research & Development, LLC
- Location
- Chapel Hill, NC + 53 other US sites
- Eligibility basics
- Ages 18+