Location · Pennsylvania
Clinical trials recruiting in Pennsylvania
943 recruiting studies have at least one site in Pennsylvania; 330 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in Pennsylvania.
943 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- Recruiting
Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)
Abbott Medical Devices
- Location
- Philadelphia, PA + 24 other US sites
- Eligibility basics
- Ages 22–70
- RecruitingPhase 3
A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder
Cybin IRL Limited
- Location
- Philadelphia, PA + 27 other US sites
- Eligibility basics
- Ages 18–85
- RecruitingPhase 3
A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease
Hoffmann-La Roche
- Location
- Hershey, PA + 91 other US sites
- Eligibility basics
- Ages 16–80
- RecruitingPhase 1/Phase 2
DFT383 in Pediatric Participants With Nephropathic Cystinosis
Novartis Pharmaceuticals
- Location
- Philadelphia, PA + 5 other US sites
- Eligibility basics
- Ages 2–5
- RecruitingPhase 3
A Study to Assess Efficacy and Safety of Empasiprubart Versus IVIg in Adults With CIDP
argenx
- Location
- Philadelphia, PA + 15 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Assess the Efficacy and Safety of Empasiprubart in Adults With CIDP
argenx
- Location
- Philadelphia, PA + 12 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
BIOTRONIK Investigation of the LivIQ Leadless Pacemaker System
Biotronik, Inc.
- Location
- Paoli, PA + 23 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Evaluate Atumelnant in Adults With Congenital Adrenal Hyperplasia
Crinetics Pharmaceuticals Inc.
- Location
- Philadelphia, PA + 12 other US sites
- Eligibility basics
- Ages 18–74
- RecruitingPhase 2/Phase 3
A Study in Pediatric Participants With Congenital Adrenal Hyperplasia (Balance-CAH)
Crinetics Pharmaceuticals Inc.
- Location
- Philadelphia, PA + 9 other US sites
- Eligibility basics
- Ages 1–17
- RecruitingPhase 3
A Maintenance Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis
Sanofi
- Location
- Pittsburgh, PA + 36 other US sites
- Eligibility basics
- Ages 16–80
- RecruitingPhase 2
ACX-362E [Ibezapolstat] for Oral Treatment of Recurrent Clostridioides Difficile Infection
Acurx Pharmaceuticals Inc.
- Location
- Pittsburgh, PA + 10 other US sites
- Eligibility basics
- Ages 18–90
- Recruiting
ReneuRx™ (Nerve Selective Therapy) Utilized in Lateral Hip Pain
Brixton Biosciences, Inc.
- Location
- King of Prussia, PA + 6 other US sites
- Eligibility basics
- Ages 22–80
- Recruiting
NORM-HF Pivotal Study
Foundry Innovation & Research 1, Limited (FIRE1)
- Location
- Philadelphia, PA + 22 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
A Phase 1/2, Open-label, Safety and Dosing Study of Autologous CART Cells (Desmoglein 3 Chimeric Autoantibody Receptor T Cells [DSG3-CAART] or CD19-specific Chimeric Antigen Receptor T Cells [CABA-201]) in Subjects With…
Cabaletta Bio
- Location
- Philadelphia, PA + 9 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
LAM-001 for the Treatment of Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
IRulya Therapeutics Inc.
- Location
- Philadelphia, PA + 1 other US site
- Eligibility basics
- Ages 18–85
- RecruitingPhase 2/Phase 3
RESET-Myositis: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Idiopathic Inflammatory Myopathy or Juvenile Idiopathic Inflammatory Myopathy
Cabaletta Bio
- Location
- Philadelphia, PA + 29 other US sites
- Eligibility basics
- Ages 6–75
- RecruitingPhase 3
A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE)
Novartis Pharmaceuticals
- Location
- Easton, PA + 16 other US sites
- Eligibility basics
- Ages 12–100
- RecruitingPhase 3
A Study to Evaluate the Efficacy and Safety of Dapirolizumab Pegol in Study Participants With Moderately to Severely Active Systemic Lupus Erythematosus
UCB Biopharma SRL
- Location
- Pittsburgh, PA + 61 other US sites
- Eligibility basics
- Ages 16+
- RecruitingPhase 3
Evaluation of Efficacy and Safety of Suzetrigine for Pain Associated With Diabetic Peripheral Neuropathy
Vertex Pharmaceuticals Incorporated
- Location
- Media, PA + 57 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 3
A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease
Pfizer
- Location
- Uniontown, PA + 76 other US sites
- Eligibility basics
- Ages 12+
- RecruitingPhase 1/Phase 2
A Study to Investigate the Safety of OpCT-001 in Adults Who Have Primary Photoreceptor Disease (CLARICO)
BlueRock Therapeutics
- Location
- Philadelphia, PA + 4 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study to Investigate Efficacy and Safety of Brivekimig in Participants With Crohn's Disease
Sanofi
- Location
- Harrisburg, PA + 18 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
A Long-Term Study to Learn About The Study Medicine Called Ritlecitinib in Children With Severe Alopecia Areata.
Pfizer
- Location
- Hershey, PA + 18 other US sites
- Eligibility basics
- Ages 6–14
- Recruiting
Study of the Shockwave Medical SkyRunner Carotid Intravascular Lithotripsy (IVL) System for the Treatment of Calcified Carotid Arteries Prior to Trans-Carotid Stenting (SKYWARD Trans-Carotid IDE [Investigational Device…
Shockwave Medical, Inc.
- Location
- Wynnewood, PA + 16 other US sites
- Eligibility basics
- Ages 18+