Healthy volunteers · Pennsylvania
Studies for healthy volunteers in Pennsylvania
330 studies have at least one recruiting site in Pennsylvania. These studies say in their official record that they accept healthy volunteers. Many are Phase 1 studies that test how a new medicine is absorbed and tolerated; others recruit healthy people as a comparison group alongside patients.
330 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteers
ProACT Post-Approval Study
Uromedica
- Location
- Allentown, PA + 13 other US sites
- Eligibility basics
- Ages 50+ · Men only
- RecruitingHealthy volunteers
Observational Study of Decentralized Urine Optical Interaction Patterns Associated With Environmental Microplastic and Nanoplastic Exposure
Ecotera Health LLC
- Location
- Philadelphia, PA + 50 other US sites
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 3
A Study of COVID-19 Vaccine(s) in Children and Adults
BioNTech SE
- Location
- Philadelphia, PA + 13 other US sites
- Eligibility basics
- Ages 5+
- RecruitingHealthy volunteers
Cholate Clearance in Fontan and Heart Failure
HepQuant, LLC
- Location
- Philadelphia, PA
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 3
A Study to Learn About the Safety of an Expanded Pneumococcal Vaccine in Healthy Infants
Pfizer
- Location
- Sayre, PA + 20 other US sites
- Eligibility basics
- Ages 1 mo–4 mo
- RecruitingHealthy volunteers
Data Collection of New Spectral CT Imaging Method
GE Healthcare
- Location
- Bethlehem, PA
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Safety and Effectiveness of Mosaic for the Treatment of Midface Volume Deficit
Helios Aesthetics Inc.
- Location
- Bryn Mawr, PA + 4 other US sites
- Eligibility basics
- Ages 22+
- RecruitingHealthy volunteers
Shield Post-Approval Study Protocol
Guardant Health, Inc.
- Location
- Altoona, PA + 48 other US sites
- Eligibility basics
- Ages 45–81
- RecruitingHealthy volunteers
Safety and Effectiveness Evaluation of the COLO-BT as an Alternative Treatment to the Ileostomy
JSR Medical Co., Ltd.
- Location
- Hershey, PA + 2 other US sites
- Eligibility basics
- Ages 19–80
- RecruitingHealthy volunteers
Non-Invasive Preeclampsia Screening and Biobank
Sequenom, Inc.
- Location
- Philadelphia, PA + 15 other US sites
- Eligibility basics
- Ages 18+ · Women only
- RecruitingHealthy volunteers
HeartBeam ECG Registry
HeartBeam, Inc.
- Location
- Pittsburgh, PA
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Aptis PRUJ Prosthesis for the Treatment of Patients With Proximal Radial Ulna Joint Disorders.
Aptis Medical
- Location
- Allentown, PA + 5 other US sites
- Eligibility basics
- Ages 18–85
- RecruitingHealthy volunteers
A Study to Determine the Effects of ENDS Flavor Availability on Abstinence Within Smokers
RAI Services Company
- Location
- Philadelphia, PA + 6 other US sites
- Eligibility basics
- Ages 21–65
- RecruitingHealthy volunteers
The Effect of Rinsing on Ocular Inflammation and Symptoms in Patients With Dry Eye Disease
Rinsada
- Location
- Pittsburgh, PA
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Identification of Breast Cancer in Breath Samples Using Trained Detection Dogs
SpotitEarly
- Location
- Philadelphia, PA + 1 other US site
- Eligibility basics
- Ages 18+ · Women only
- RecruitingHealthy volunteers
Pupillometry in Identifying Risk of Postoperative Opioid-induced Respiratory Depression in Children Undergoing Tonsillectomy
NeurOptics Inc
- Location
- Pittsburgh, PA
- Eligibility basics
- Ages 3–17
- RecruitingHealthy volunteersPhase 2
A Study to Learn About mRNA Vaccines Against Influenza in Adults
Pfizer
- Location
- Philadelphia, PA + 14 other US sites
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 3
A Study to Learn About the Safety, Tolerability, and Immunogenicity of a Fifth Dose of 6-Valent OspA-Based Lyme Disease Vaccine
Pfizer
- Location
- Duncansville, PA + 10 other US sites
- Eligibility basics
- Ages 7+
- RecruitingHealthy volunteers
Acellular Dermal Matrix Investigation in Breast Reconstruction
RTI Surgical
- Location
- Philadelphia, PA + 11 other US sites
- Eligibility basics
- Ages 22+ · Women only
- RecruitingHealthy volunteers
Rezdiffra Pregnancy and Lactation Registry
Madrigal Pharmaceuticals, Inc.
- Location
- West Conshohocken, PA
- Eligibility basics
- Any age listed · Women only
- RecruitingHealthy volunteers
Helix Research Network
Helix, Inc
- Location
- Bethlehem, PA + 13 other US sites
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
A Study Evaluating the Safety and Efficacy of the 3M™ V.A.C. Peel and Place Dressing
Solventum US LLC
- Location
- Bethlehem, PA + 2 other US sites
- Eligibility basics
- Ages 22+
- RecruitingHealthy volunteers
Novel Self-charging, Medical-Grade Smart Insoles With AI/ML Edge Computing to Monitor Biometrics.
Spectrum Ergonomics and Occupational Health Services
- Location
- Williamsport, PA
- Eligibility basics
- Ages 18–90
- RecruitingHealthy volunteers
Observational, Passive Surveillance Program to Collect Information on Women and Their Offspring Exposed to MenQuadfi® During Pregnancy, in United States (US)
Sanofi Pasteur, a Sanofi Company
- Location
- Swiftwater, PA
- Eligibility basics
- Any age listed
Who these studies look for
“Healthy” is decided at screening, not by you. Sites usually check vital signs, blood and urine tests, an ECG, your medications and sometimes your BMI or smoking status. A study can still turn you away for reasons that have nothing to do with being unwell, such as timing or a full roster.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Do healthy volunteer studies pay?
Many do, because volunteers give up time and follow strict schedules, but amounts are set by each study and are usually only confirmed by the research site. When a record states an amount we show the exact wording; otherwise we say compensation is not disclosed.
What happens at a screening visit?
Expect consent paperwork first, then a health questionnaire, vital signs, blood and urine samples and often an ECG. You can ask questions and withdraw at any time, before or after you sign.