Phase 1 · St. Louis area, MO
Phase 1 clinical trials in St. Louis area, MO
35 recruiting studies have a site in the St. Louis area. This page includes nearby cities such as Saint Louis, Chesterfield, Creve Coeur, Florissant.
35 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 1/Phase 2
A Study of SGT-003 Gene Therapy in Duchenne Muscular Dystrophy (INSPIRE DUCHENNE)
Solid Biosciences Inc.
- Location
- St Louis, MO + 11 other US sites
- Eligibility basics
- Ages 0 mo–17 · Men only
- RecruitingPhase 1/Phase 2
Gene Correction in Autologous CD34+ Hematopoietic Stem Cells (HbS to HbA) to Treat Severe Sickle Cell Disease
Kamau Therapeutics
- Location
- St Louis, MO + 5 other US sites
- Eligibility basics
- Ages 12–50
- RecruitingPhase 1/Phase 2
A Phase 1b/2 Study of CAR T Cell Therapy Targeting CD19 and BCMA in Participants With Relapsed or Refractory AL Amyloidosis.
Alexion Pharmaceuticals, Inc.
- Location
- St Louis, MO + 9 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
Study of BHV-1400 in IgA Nephropathy
Biohaven Therapeutics Ltd.
- Location
- Chesterfield, MO + 13 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 1/Phase 2
A Study Exploring Changes in a Variety of Biomarkers Following Dosing With MT1988 in Participants at Clinical High Risk for Psychosis
Monument Therapeutics Limited
- Location
- St Louis, MO + 14 other US sites
- Eligibility basics
- Ages 17–30
- RecruitingPhase 1/Phase 2
Evaluate REC-4881 in Participants With Familial Adenomatous Polyposis (FAP)
Recursion Pharmaceuticals Inc.
- Location
- St Louis, MO + 6 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
Study of EXE-346 Live Biotherapeutic to Reduce High Bowel Movement Frequency in Subjects With an IPAA (PROF)
Exegi Pharma, LLC
- Location
- St Louis, MO + 7 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
A Study Comparing KB801 Verse Placebo in Patients With Stage 2 or 3 Neurotrophic Keratitis
Krystal Biotech, Inc.
- Location
- Town and Country, MO + 6 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
Study to Evaluate the Pharmacokinetics and Safety of EXPAREL for Postoperative Analgesia in Subjects Undergoing Cardiac Surgery
Pacira Pharmaceuticals, Inc
- Location
- St Louis, MO + 4 other US sites
- Eligibility basics
- Ages 0 mo–6
- RecruitingPhase 1/Phase 2
Treatment of Moderate to Severe Refractory Crohn's Disease
Tr1X, Inc.
- Location
- St Louis, MO + 12 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 1/Phase 2
Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Reduced Ejection Fraction
Sardocor Corp.
- Location
- St Louis, MO + 4 other US sites
- Eligibility basics
- Ages 18–80
Who these studies look for
Phase 1 studies often have narrow eligibility: specific age and weight ranges, no recent participation in another study, no nicotine, and limits on medications. Some Phase 1 studies recruit patients rather than healthy volunteers, so check each listing.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.