Weight loss · St. Louis area, MO
Weight loss and obesity studies in St. Louis area, MO
19 recruiting studies have a site in the St. Louis area. This page includes nearby cities such as Saint Louis, Chesterfield, Creve Coeur, Florissant.
19 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteersPhase 3
A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)
Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics
- Location
- Chesterfield, MO + 55 other US sites
- Eligibility basics
- Ages 18–79
- RecruitingPhase 3
A Study to Learn About Switching to a Monthly Study Medicine Called Berobenatide (PF-08653944) to Help Keep Weight Off in People With Overweight or Obesity
Pfizer
- Location
- Chesterfield, MO + 4 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Master Protocol to Investigate Efficacy and Safety of Elecoglipron in Participants With Obesity or Overweight With or Without T2DM
AstraZeneca
- Location
- Kansas City, MO + 43 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity
Amgen
- Location
- City of Saint Peters, MO + 136 other US sites
- Eligibility basics
- Ages 45–99
- RecruitingPhase 3
A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes
Eli Lilly and Company
- Location
- Chesterfield, MO + 59 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study of Eloralintide (LY3841136) in Participants With Obstructive Sleep Apnea and Obesity or Overweight
Eli Lilly and Company
- Location
- St Louis, MO + 22 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study
Eli Lilly and Company
- Location
- St Louis, MO + 36 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 3
Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight
Eli Lilly and Company
- Location
- St Louis, MO + 34 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 3
A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide
Novo Nordisk A/S
- Location
- St Louis, MO + 32 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin
Eli Lilly and Company
- Location
- Chesterfield, MO + 55 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
AMBITION 7: A Research Study Investigating How Well Zenagamtide Lowers Blood Sugar and Body Weight Compared to Insulin Glargine in People With Type 2 Diabetes and Increased Risk of Diseases That Affect the Heart and…
Novo Nordisk A/S
- Location
- St Louis, MO + 55 other US sites
- Eligibility basics
- Ages 45+
- RecruitingPhase 3
Efficacy and Safety of Aleniglipron in Participants With Obesity or Overweight With a Weight-Related Comorbidity (ACCOMPLISH-1)
Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics
- Location
- Hazelwood, MO + 12 other US sites
- Eligibility basics
- Ages 18–79
- RecruitingHealthy volunteers
Two-Week Stair-Climbing Exercise Snacks and Metabolic Health in Adults With Overweight or Obesity: A Pilot Study
St. Louis University
- Location
- St Louis, MO
- Eligibility basics
- Ages 18–35
- RecruitingHealthy volunteers
Role of KATP Channel Loss in Type 2 Diabetes
Washington University School of Medicine
- Location
- St Louis, MO
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteers
Advancing Biopsychosocial Care Training Initiative
Washington University School of Medicine
- Location
- St Louis, MO
- Eligibility basics
- Ages 5+
- RecruitingHealthy volunteers
Small Extracellular Vesicles and Insulin Action
Washington University School of Medicine
- Location
- St Louis, MO
- Eligibility basics
- Ages 25–55
- RecruitingHealthy volunteersPhase 2
Effect of Ketone Esters on Liver Fat Content and Metabolic Function
Washington University School of Medicine
- Location
- St Louis, MO
- Eligibility basics
- Ages 18–40
- RecruitingHealthy volunteers
Alzheimer"s Imaging Biomarkers in Obesity
Cyrus A Raji
- Location
- St Louis, MO
- Eligibility basics
- Ages 40–60
- RecruitingHealthy volunteers
Brain Health in Youth With Normal Weight, Overweight and Obesity at Risk for Type 2 Diabetes (T2D)
Washington University School of Medicine
- Location
- St Louis, MO + 1 other US site
- Eligibility basics
- Ages 12–17
Who these studies look for
Most of these studies set a BMI range and may exclude people taking certain weight-loss medicines or who have had bariatric surgery. Some require a weight-related condition such as type 2 diabetes or high blood pressure.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.