Phase 1 · New York
Phase 1 clinical trials in New York
97 studies have at least one recruiting site in New York. Phase 1 (and early Phase 1) trials are usually the first time a medicine is studied in people. They are typically small, closely monitored, and many are run in dedicated research units, sometimes with overnight stays.
97 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteersPhase 1
Glutamatergic Mechanisms: Aim2
New York State Psychiatric Institute
- Location
- New York, NY
- Eligibility basics
- Ages 18–55
- RecruitingHealthy volunteersPhase 1
Clinical Trial to Evaluate the Safety and Immunogenicity of the V2 Apex-Directed Immunogens DV201P-RNA and DV202B1-RNA in Adult Participants Without HIV
National Institute of Allergy and Infectious Diseases (NIAID)
- Location
- New York, NY + 6 other US sites
- Eligibility basics
- Ages 18–55
- RecruitingHealthy volunteersPhase 1
Mifepristone vs Misoprostol
Montefiore Medical Center
- Location
- The Bronx, NY
- Eligibility basics
- Ages 18–45 · Women only
- RecruitingHealthy volunteersEarly Phase 1
Spinal Cord Associative Plasticity Study
Columbia University
- Location
- New York, NY + 2 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingHealthy volunteersPhase 1/Phase 2
Abemaciclib in Combination With Bicalutamide for Androgen Receptor-positive, HER2-negative Metastatic Breast Cancer
Icahn School of Medicine at Mount Sinai
- Location
- New York, NY + 2 other US sites
- Eligibility basics
- Ages 18–90
- RecruitingHealthy volunteersPhase 1
E-CEL UVEC Treatment for Anal Fissures
Weill Medical College of Cornell University
- Location
- New York, NY
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 1
MDMA-Assisted Therapy for Mental Healthcare Providers
Rachel Yehuda
- Location
- New York, NY
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersEarly Phase 1
Chronic Transcutaneous Stimulation to Promote Motor Function and Recovery in Individuals With Paralysis or Paresis
Northwell Health
- Location
- Manhasset, NY
- Eligibility basics
- Ages 18–75
- RecruitingHealthy volunteersEarly Phase 1
Anxiety During Abstinence in AUD
Columbia University
- Location
- New York, NY
- Eligibility basics
- Ages 21–55
- RecruitingHealthy volunteersEarly Phase 1
Predictors of Aspirin Failure in Preeclampsia Prevention
Rockefeller University
- Location
- New York, NY
- Eligibility basics
- Ages 18–45 · Women only
- RecruitingHealthy volunteersPhase 1
Repetitive Transcranial Magnetic Stimulation for Post-concussion Headaches
State University of New York - Upstate Medical University
- Location
- Syracuse, NY
- Eligibility basics
- Ages 18–55
- RecruitingPhase 1
Phase 1b Study of VERVE-201 in Patients With Refractory Hyperlipidemia
Verve Therapeutics, Inc.
- Location
- New York, NY + 4 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 1
A Study of CLN-978, a Subcutaneously Administered CD19-directed T Cell Engager, in Subjects With Systemic Lupus Erythematosus
Cullinan Therapeutics Inc.
- Location
- New York, NY + 10 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 1/Phase 2
A Multicenter Study to Evaluate Safety, Tolerability, and Clinical Responses of DSP-1083 Into Subjects With Parkinson's Disease
Sumitomo Pharma America, Inc.
- Location
- New York, NY + 2 other US sites
- Eligibility basics
- Ages 40–72
- RecruitingPhase 1/Phase 2
An AAV Gene Therapy Trial of AFTX-201 in Adults With BAG3-Associated Dilated Cardiomyopathy (DCM)
Affinia Therapeutics
- Location
- New York, NY + 3 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 1/Phase 2
RESET-MG: A Study to Evaluate the Safety and Efficacy of CABA-201 in Participants With Generalized Myasthenia Gravis
Cabaletta Bio
- Location
- New York, NY + 16 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 1
Study of KITE-363 in Participants With Autoimmune Neurologic Diseases That Did Not Respond to Usual Treatment
Kite, A Gilead Company
- Location
- New York, NY + 4 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1/Phase 2
A Phase 1/2, Open-label, Safety and Dosing Study of Autologous CART Cells (Desmoglein 3 Chimeric Autoantibody Receptor T Cells [DSG3-CAART] or CD19-specific Chimeric Antigen Receptor T Cells [CABA-201]) in Subjects With…
Cabaletta Bio
- Location
- New York, NY + 9 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
Safety and Efficacy of Soquelitinib in Adults With Hidradenitis Suppurativa
Corvus Pharmaceuticals, Inc.
- Location
- New York, NY + 8 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
A Study in People With Diabetic Macular Edema to Test How Well Different Doses of BI 3812465 Are Tolerated
Boehringer Ingelheim
- Location
- Oceanside, NY + 24 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
Study to Evaluate the Pharmacokinetics (PK), Safety and Tolerability up to 6 Years of Intravenous (i.v.) Secukinumab in Pediatric Participants With Juvenile Psoriatic Arthritis (JPsA).
Novartis Pharmaceuticals
- Location
- New York, NY + 10 other US sites
- Eligibility basics
- Ages 2–17
- RecruitingPhase 1/Phase 2
A Study to Evaluate Topical ATR04-484 for EGFRi-Associated Dermal Toxicity
Azitra Inc.
- Location
- New York, NY + 5 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
A Clinical Study of Letermovir (MK-8228) in Children and Adolescents Who Receive a Kidney Transplant (KT) (MK-8228-077)
Merck Sharp & Dohme LLC
- Location
- New York, NY + 20 other US sites
- Eligibility basics
- Up to age 17
- RecruitingPhase 1/Phase 2
A Gene Therapy Study of SPK-8011QQ in Adults With Severe or Moderately Severe Hemophilia A
Hoffmann-La Roche
- Location
- New York, NY + 5 other US sites
- Eligibility basics
- Ages 18+ · Men only
Who these studies look for
Phase 1 studies often have narrow eligibility: specific age and weight ranges, no recent participation in another study, no nicotine, and limits on medications. Some Phase 1 studies recruit patients rather than healthy volunteers, so check each listing.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Are Phase 1 trials riskier?
Every study carries risk. Phase 1 studies involve less human data about the product, which is why they are closely monitored. The informed consent document explains the known risks; read it carefully and ask questions before signing.
Why do some Phase 1 studies include overnight stays?
Staying in the unit lets staff dose on a precise schedule and collect samples around the clock. Where a record mentions an inpatient stay we flag it on the listing.