Phase 1 · New York
Phase 1 clinical trials in New York
97 studies have at least one recruiting site in New York. Phase 1 (and early Phase 1) trials are usually the first time a medicine is studied in people. They are typically small, closely monitored, and many are run in dedicated research units, sometimes with overnight stays.
97 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteersPhase 1/Phase 2
A Phase I/II Study of ITU512 in Healthy Participants and Patients With Sickle Cell Disease
Novartis Pharmaceuticals
- Location
- New York, NY + 7 other US sites
- Eligibility basics
- Ages 12–55
- RecruitingHealthy volunteersPhase 1/Phase 2
Phase 1/2 Study of Respiratory Syncytial Virus and Human Metapneumovirus (RSV+HMPV) Vaccine Candidate in Adults 60 Years of Age and Older
Sanofi
- Location
- Staten Island, NY + 49 other US sites
- Eligibility basics
- Ages 60+
- RecruitingHealthy volunteersPhase 1
A Clinical Study of Novel Pneumococcal Vaccine V118C in Children (V118C-002)
Merck Sharp & Dohme LLC
- Location
- East Syracuse, NY + 14 other US sites
- Eligibility basics
- Ages 2 mo–1
- RecruitingHealthy volunteersPhase 1/Phase 2
Study of XmAb942 in Healthy Participants and Participants With Ulcerative Colitis
Xencor, Inc.
- Location
- Albany, NY + 27 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingHealthy volunteersPhase 1
A Study of BBT001 in Healthy Volunteers (HVs) and in Adult Patients With Atopic Dermatitis (AD)
Bambusa Therapeutics
- Location
- New York, NY + 2 other US sites
- Eligibility basics
- Ages 18–72
- RecruitingHealthy volunteersPhase 1/Phase 2
Study to Assess Safety and Immunogenicity of an Egg-based H5N8 Influenza Vaccine at Multiple Dose Levels Adjuvanted With Matrix-M in Healthy Participants 18 Years of Age and Above.
Sanofi
- Location
- Rochester, NY + 15 other US sites
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 1
A Clinical Trial Investigating the Safety and Biological Activity of the Antibody BNT351 in Adults Living Without and With HIV
BioNTech SE
- Location
- New York, NY + 3 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 1/Phase 2
Study of GS-4321 in Healthy Participants and Participants With Chronic Hepatitis Delta Virus
Gilead Sciences
- Location
- New York, NY + 4 other US sites
- Eligibility basics
- Ages 18–69
- RecruitingHealthy volunteersPhase 1
A Study of [18F]LY4214835 in Healthy Volunteers and Participants With Cancer
Eli Lilly and Company
- Location
- New York, NY + 1 other US site
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 1
A Study of BBT002 in Healthy Volunteers (HVs) and in Adult Patients With Chronic Obstructive Pulmonary Disease (COPD) or Chronic Rhiosininusitis With Nasal Polyps (CRSwNP)
Bambusa Therapeutics
- Location
- New York, NY + 1 other US site
- Eligibility basics
- Ages 18–80
- RecruitingHealthy volunteersPhase 1
Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics And Pharmacodynamics of SIF001 in Healthy Subjects and in Epilepsy Patients
Suninflam Inc
- Location
- Amherst, NY + 9 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingHealthy volunteersPhase 1
A Study to Learn About a Vaccine Against E Coli in Healthy Adults
Pfizer
- Location
- New York, NY + 9 other US sites
- Eligibility basics
- Ages 18–64
- RecruitingHealthy volunteersPhase 1/Phase 2
A Study on the Safety and Immune Response of a Urinary Tract Infection (UTI) Vaccine in Adults 18-64 Years of Age and Clinical Efficacy in Females 18-64 Years of Age
GlaxoSmithKline
- Location
- Rochester, NY + 5 other US sites
- Eligibility basics
- Ages 18–64
- RecruitingHealthy volunteersPhase 1
A Study of ORX142 in Healthy Adult Subjects, Including Subjects 18 to 80 Years of Age
Centessa Pharmaceuticals (UK) Limited
- Location
- New York, NY + 2 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingHealthy volunteersPhase 1
The Objective of This Phase 1 Study is to Evaluate the Food Effect of 100 mg Hezkue Turbo® (ASP-001.1, Sildenafil) Under Fed Versus 100 mg of Hezkue Turbo® (ASP-001.1, Sildenafil) Under Fasted Conditions in Healthy…
Aspargo Labs, Inc
- Location
- New York, NY
- Eligibility basics
- Ages 20–70 · Men only
- RecruitingPhase 1Overnight stay mentioned
A Study of GNTI-122 in Adults Recently Diagnosed With T1D
GentiBio, Inc
- Location
- New York, NY + 8 other US sites
- Eligibility basics
- Ages 18–55
- RecruitingHealthy volunteersEarly Phase 1
Sensory Tests of Cigarettes for Identification of Flavors in Current Daily Smoking Adults
Roswell Park Cancer Institute
- Location
- Buffalo, NY
- Eligibility basics
- Ages 21+
- RecruitingHealthy volunteersPhase 1
Danvatirsen Monotherapy Followed by Combination With Venetoclax in Relapsed/Refractory MDS & AML
Montefiore Medical Center
- Location
- The Bronx, NY + 1 other US site
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersEarly Phase 1
Testosterone and Neural Function in Men With Spinal Cord Injury
VA Office of Research and Development
- Location
- The Bronx, NY
- Eligibility basics
- Ages 18–80 · Men only
- RecruitingHealthy volunteersPhase 1
Safety and Tolerability Trial of Psilocybin in Healthy Older Adults
University of Colorado, Denver
- Location
- New York, NY + 5 other US sites
- Eligibility basics
- Ages 65–85
- RecruitingHealthy volunteersPhase 1/Phase 2
Study of Cannabidiol and Neuroimaging on Stress
Icahn School of Medicine at Mount Sinai
- Location
- New York, NY
- Eligibility basics
- Ages 18–25
- RecruitingHealthy volunteersPhase 1
Alpelisib Challenge Test (ACT)
Columbia University
- Location
- New York, NY
- Eligibility basics
- Ages 18–70
- RecruitingHealthy volunteersPhase 1
Safety and Pharmacokinetics Study of PGT121.414.LS Alone and in Combination With VRC07-523LS in Infants Exposed to HIV-1
National Institute of Allergy and Infectious Diseases (NIAID)
- Location
- The Bronx, NY + 4 other US sites
- Eligibility basics
- Any age listed
- RecruitingHealthy volunteersPhase 1
Human Models of Selective Insulin Resistance: Alpelisib, Part I
Columbia University
- Location
- New York, NY
- Eligibility basics
- Ages 18–70
Who these studies look for
Phase 1 studies often have narrow eligibility: specific age and weight ranges, no recent participation in another study, no nicotine, and limits on medications. Some Phase 1 studies recruit patients rather than healthy volunteers, so check each listing.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Are Phase 1 trials riskier?
Every study carries risk. Phase 1 studies involve less human data about the product, which is why they are closely monitored. The informed consent document explains the known risks; read it carefully and ask questions before signing.
Why do some Phase 1 studies include overnight stays?
Staying in the unit lets staff dose on a precise schedule and collect samples around the clock. Where a record mentions an inpatient stay we flag it on the listing.