Phase 1 · Texas
Phase 1 clinical trials in Texas
202 studies have at least one recruiting site in Texas. Phase 1 (and early Phase 1) trials are usually the first time a medicine is studied in people. They are typically small, closely monitored, and many are run in dedicated research units, sometimes with overnight stays.
202 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 1
A Study on the Safety and Immune Response of Investigational mRNA Seasonal Flu/COVID-19 Combination Vaccine in Adults
GlaxoSmithKline
- Location
- Austin, TX + 11 other US sites
- Eligibility basics
- Ages 65–85
- RecruitingPhase 1
Study of BHV-1400 in IgA Nephropathy
Biohaven Therapeutics Ltd.
- Location
- Houston, TX + 13 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingEarly Phase 1
VTP-1000 in Adults With Celiac Disease
Barinthus Biotherapeutics
- Location
- Austin, TX + 15 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 1
A Study to Evaluate the Safety and Tolerability of Different Doses of CX11 Tablets
Corxel Pharmaceuticals
- Location
- Austin, TX + 1 other US site
- Eligibility basics
- Ages 18–55 · Women only
- RecruitingPhase 1
R-2487 in Patients With Rheumatoid Arthritis
Rise Therapeutics LLC
- Location
- Houston, TX + 5 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1
A Study of Efimosfermin Alfa in Adults With Hepatic Impairment
GlaxoSmithKline
- Location
- San Antonio, TX + 2 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 1/Phase 2
Evaluate REC-4881 in Participants With Familial Adenomatous Polyposis (FAP)
Recursion Pharmaceuticals Inc.
- Location
- Dallas, TX + 6 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
A Phase 1/2 Study of NKX019 in Subjects With Autoimmune Disease (Ntrust-1)
Nkarta, Inc.
- Location
- Dallas, TX + 15 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1/Phase 2
Phase 1/2 Open-Label Dose-Escalation Study to Evaluate Safety of a Single Intravitreal Injection of RTx-021 in Patients With Stargardt Disease
Ray Therapeutics, Inc.
- Location
- Bellaire, TX + 2 other US sites
- Eligibility basics
- Ages 16+
- RecruitingPhase 1
AMX0114 in Adult Participants With Amyotrophic Lateral Sclerosis
Amylyx Pharmaceuticals Inc.
- Location
- Houston, TX + 9 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
Study to Evaluate the Safety and Efficacy of CSB-001 Ophthalmic Solution 0.1% in Subjects With Corneal Scars
Claris Biotherapeutics, Inc.
- Location
- San Antonio, TX + 6 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 1/Phase 2
Anti-VEGF Gene Therapy Trial for Vestibular Schwannoma
Akouos, Inc.
- Location
- Dallas, TX + 3 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
A Phase 1b Study of Budoprutug in Systemic Lupus Erythematosus (SLE)
Climb Bio, Inc.
- Location
- Allen, TX + 1 other US site
- Eligibility basics
- Ages 18–65
- RecruitingPhase 1/Phase 2
A Study to Assess the Long-term Safety and Clinical Activity of mRNA-3927 in Participants Previously Enrolled in the mRNA-3927-P101 Study
ModernaTX, Inc.
- Location
- Houston, TX + 5 other US sites
- Eligibility basics
- Ages 1+
- RecruitingPhase 1/Phase 2
Multi-center, Open-label, Single-ascending Dose Study of Safety and Tolerability of TN-201 in Adults With Symptomatic MYBPC3 Mutation-associated HCM
Tenaya Therapeutics
- Location
- Houston, TX + 4 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1/Phase 2
Allogeneic HB-adMSCs vs Placebo for the Treatment of Acute Kidney Injury
Hope Biosciences LLC
- Location
- Houston, TX
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1/Phase 2
Safety and Tolerability Subretinal OPGx-001 for LCA5-Associated Inherited Retinal Degeneration (LCA5-IRD) and Non-interventional Arm With Untreated Patients
Opus Genetics, Inc
- Location
- Dallas, TX + 1 other US site
- Eligibility basics
- Ages 4+
- RecruitingPhase 1/Phase 2
Evaluation of ELU42 Topical Spray for the Treatment of Diabetic Foot Ulcers
Eluciderm Inc
- Location
- McAllen, TX + 3 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1/Phase 2
A Phase 1b/2 Study of IM-101 in Adult Participants With Generalized Myasthenia Gravis and Ocular Myasthenia Gravis
ImmunAbs Inc.
- Location
- Houston, TX + 3 other US sites
- Eligibility basics
- Ages 18–74
- RecruitingPhase 1/Phase 2
Open-Label Study of mRNA-3927 in Participants With Propionic Acidemia
ModernaTX, Inc.
- Location
- Houston, TX + 7 other US sites
- Eligibility basics
- Any age listed
- RecruitingPhase 1/Phase 2
A Phase 1/2 Study of NRTX-1001 Neuronal Cell Therapy in Drug-Resistant Bilateral Mesial Temporal Lobe Epilepsy (MTLE)
Neurona Therapeutics
- Location
- Houston, TX + 15 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1
Study to Evaluate the Pharmacokinetics and Safety of EXPAREL for Postoperative Analgesia in Subjects Undergoing Cardiac Surgery
Pacira Pharmaceuticals, Inc
- Location
- Houston, TX + 4 other US sites
- Eligibility basics
- Ages 0 mo–6
- RecruitingPhase 1
Safety and Pharmacokinetics of LPX-TI641 in Atopic Dermatitis and Psoriasis
LAPIX Therapeutics Inc.
- Location
- Dallas, TX + 1 other US site
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
A Phase 1/2, Dose-Exploration Study to Evaluate the Safety and Efficacy of BEAM-301 in Patients With Glycogen Storage Disease Type Ia (GSDIa)
Beam Therapeutics Inc.
- Location
- Houston, TX + 2 other US sites
- Eligibility basics
- Ages 18+
Who these studies look for
Phase 1 studies often have narrow eligibility: specific age and weight ranges, no recent participation in another study, no nicotine, and limits on medications. Some Phase 1 studies recruit patients rather than healthy volunteers, so check each listing.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Are Phase 1 trials riskier?
Every study carries risk. Phase 1 studies involve less human data about the product, which is why they are closely monitored. The informed consent document explains the known risks; read it carefully and ask questions before signing.
Why do some Phase 1 studies include overnight stays?
Staying in the unit lets staff dose on a precise schedule and collect samples around the clock. Where a record mentions an inpatient stay we flag it on the listing.