Phase 1 · Texas
Phase 1 clinical trials in Texas
202 studies have at least one recruiting site in Texas. Phase 1 (and early Phase 1) trials are usually the first time a medicine is studied in people. They are typically small, closely monitored, and many are run in dedicated research units, sometimes with overnight stays.
202 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 1
Single and Multiple Dose Escalation of PHIN-214 in Child-Pugh A and B Liver Cirrhotics
PharmaIN
- Location
- Dallas, TX + 8 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1
A Study of KB408 for the Treatment of Alpha-1 Antitrypsin Deficiency
Krystal Biotech, Inc.
- Location
- The Woodlands, TX + 2 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 1/Phase 2
A Phase 1/2, First-in-Human Dose Escalation/Expansion Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of a Subretinal Injection of SB-007 in Subjects With Stargardt Disease (STGD1)
Splice Bio
- Location
- Dallas, TX + 4 other US sites
- Eligibility basics
- Ages 12–65
- RecruitingPhase 1
Study Assessing Left Ventricular Administration of a Genetic Medicine Directing Organ Regeneration in Heart Failure
Medley Therapeutics
- Location
- Houston, TX
- Eligibility basics
- Ages 18–79
- RecruitingPhase 1
Study in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF)
Secretome Therapeutics
- Location
- Dallas, TX
- Eligibility basics
- Ages 18+
- RecruitingEarly Phase 1
Safety and Feasibility of Umbilical Cord Wharton's Jelly Allograft Injections for Knee Osteoarthritis
R3 Medical Research
- Location
- Cleveland, TX + 4 other US sites
- Eligibility basics
- Ages 30+
- RecruitingPhase 1/Phase 2
Pharmacokinetics, Safety, Tolerability of Dolutegravir/Rilpivirine in Pediatrics
ViiV Healthcare
- Location
- Houston, TX + 5 other US sites
- Eligibility basics
- Ages 6–12
- RecruitingPhase 1
Safety and Feasibility of Umbilical Cord Wharton's Jelly Allograft Injections for Lumbar Pain
R3 Stem Cell
- Location
- Cleveland, TX + 3 other US sites
- Eligibility basics
- Ages 20+
- RecruitingPhase 1/Phase 2
Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Reduced Ejection Fraction
Sardocor Corp.
- Location
- Dallas, TX + 4 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 1/Phase 2
Study of TL-895 Combined With Ruxolitinib in JAKi Treatment-Naïve MF Subjects and Subjects With MF Who Have a Suboptimal Response to Ruxolitinib
Telios Pharma, Inc.
- Location
- Houston, TX + 3 other US sites
- Eligibility basics
- Ages 18+
Who these studies look for
Phase 1 studies often have narrow eligibility: specific age and weight ranges, no recent participation in another study, no nicotine, and limits on medications. Some Phase 1 studies recruit patients rather than healthy volunteers, so check each listing.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Are Phase 1 trials riskier?
Every study carries risk. Phase 1 studies involve less human data about the product, which is why they are closely monitored. The informed consent document explains the known risks; read it carefully and ask questions before signing.
Why do some Phase 1 studies include overnight stays?
Staying in the unit lets staff dose on a precise schedule and collect samples around the clock. Where a record mentions an inpatient stay we flag it on the listing.