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Molecular Genetics Studies of Cancer Patients and Their Relatives

City of Hope Medical Center · with National Cancer Institute (NCI) · NCT04185935

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Any age listed · All sexes
Healthy volunteers
Accepted
Study type
Observational
Target enrollment
999999
US sites recruiting
34
Study start
April 18, 1997
Record last updated
June 29, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

This trial studies the genetic and behavioral factors that may contribute to the development of specific cancers and how these factors may affect the outcome of the disease in patients with a history of cancer and their relatives.

Being studied: Biospecimen Collection; Questionnaire Administration

Conditions: Malignant Neoplasm

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria

Inclusion Criteria

  • Individuals must have a personal history of cancer and/or a family history of cancer suggestive of the presence of an inherited predisposition. This inherited predisposition might manifest as:
  • Young age cancer diagnosis
  • Multiple primary neoplasms in affected member
  • The presence of rare tumor types in the family
  • Congenital malformations
  • Any other family clustering of cancer
  • Any other cancer-predisposing genetic diseases/conditions
  • Individuals may also be eligible by participation in the City of Hope Cancer Screening \& Prevention Program Network (CSPPN) clinical service or on the basis of membership in a group known or suspected to have an increased risk of carrying a genetic alteration or of sustaining a particular exposure that would place that at increased risk of cancer. (Examples would include members of occupational cohorts like asbestos workers, individuals with multiple dysplastic nevi in the absence of a family history of cancer, and individuals descended from a particular tribe in the American Southwest who have an increased incidence of a rare genetic alteration associated with an increased risk of a specific cancer.)
  • Individuals and families may be referred to us in a number of different ways. After initial contact is made with a individual or family by family studies personnel; an individual within the bloodline will be identified as the historian. There may be more than one historian within a family
  • At least one historian must be wiling to provide information or access as needed to contact appropriate family members for documentation of cancer and for consent. An individual is considered to be eligible to participate if they criteria; contact with relatives is not always indicated
  • Individuals who are under 18 are eligible for study if they meet the criteria. Consent for participation must be given by a legal guardian or parent
  • Deceased patients may be included in the study. Public records, such as death certificates, can be used to confirm information from individuals or family members. If medical records are needed, consent for these records will be obtained from the deceased's next of kin. Next of kin refers to the following hierarchy of relatives; spouse, offspring, parents, and siblings. (Any further use of next of kin in this protocol should relate back to this hierarchy.) Archived tissue samples, such as pathology blocks or snap frozen tumor from a pathology department tumor bank (discard specimens) may be used for genetic research

Exclusion Criteria

  • A family may be ineligible for study if the historian will not allow access to anyone within the family and thus, the accuracy of the family history cannot be established

Recruiting US locations

  • Valleywise Comprehensive Health Center - Phoenix

    Phoenix, AZ 85008

    Site contact: Ian K. Komenaka · 602-344-5368 · Ian_Komenaka@dmgaz.org

  • John Muir Medical Center-Concord Campus

    Concord, CA 94520

    Site contact: Shellie Campos · 925-947-3322 · shellie.campos@johnmuirhealth.com

  • City of Hope Medical Center

    Duarte, CA 91010

    Site contact: Jeffrey N. Weitzel · 626-218-4334 · jweitzel@coh.org

  • Saint Jude Medical Center

    Fullerton, CA 92835

    Site contact: William E. Lawler · 714-446-5801 · William.Lawlor@StJoe.org

  • Saddleback Memorial Medical Center

    Laguna Hills, CA 92653

    Site contact: Jeffrey N. Weitzel · 626-218-4334 · jweitzel@coh.org

  • USC / Norris Comprehensive Cancer Center

    Los Angeles, CA 90033

    Site contact: Charite Ricker · 323-409-7710 · Charite.Ricker@med.usc.edu

  • Saint Joseph Hospital - Orange

    Orange, CA 92868

    Site contact: Jeffrey N. Weitzel · 626-218-4334 · jweitzel@coh.org

  • Sutter Cancer Centers Radiation Oncology Services-Roseville

    Roseville, CA 95661

    Site contact: Kristie A. Bobolis · 916-782-5106 · bobolis@surewest.net

  • Cancer Center of Santa Barbara

    Santa Barbara, CA 93105

    Site contact: Frederic C. Kass · 805-563-5854 · fkass@ccsb.org

  • Lynn Regional Cancer Center - West

    Boca Raton, FL 33428

    Site contact: Louise E. Morrell · 561-955-2141 · LMorrell@brrh.com

  • Holy Cross Hospital

    Fort Lauderdale, FL 33308

    Site contact: Zdenka E. Segota · 954-267-7709 · Ena.segota@holy-cross.com

  • Kootenai Cancer Center

    Post Falls, ID 83854

    Site contact: Jeffrey W. Allen · 208-625-4728 · Mhander@kh.org

  • John H Stroger Jr Hospital of Cook County

    Chicago, IL 60612

    Site contact: Pamela Ganschow · 312-864-4436 · pganschow@cookcountyhhs.org

  • Rush University Medical Center

    Chicago, IL 60612

    Site contact: Lydia Usha · 312-563-2200 · Lydia_Usha@rush.edu

  • Mercy Hospital

    Cedar Rapids, IA 52403

    Site contact: Amie Hass · 319-398-6732 · ahass@mercycare.org

  • Suburban Hospital

    Bethesda, MD 20814

    Site contact: Carolyn B. Hendricks · 301-897-1503 · carolyn.hendricks53@verizon.net

  • Frederick Oncology Hematology Associates

    Frederick, MD 21702

    Site contact: Patricia A. Rice · 301-418-5010 · price@fmh.org

  • Steward Saint Elizabeth's Medical Center

    Brighton, MA 02135

    Site contact: Beth B. Herrick · 617-789-3232 · Beth.Herrick@steward.org

  • Hunterdon Medical Center

    Flemington, NJ 08822

    Site contact: Kenneth B. Blankstein · 908-788-2566 · kblankstein@hhpnj.org

  • Lovelace Medical Center-Downtown

    Albuquerque, NM 87102

    Site contact: Malcolm H. Purdy · 505-727-3040 · malcolm.purdy@ardenthealth.com

  • New Mexico Oncology Hematology Consultants

    Albuquerque, NM 87109

    Site contact: Annette C. Fontaine · 505-480-1462 · afontaine@nmohc.com

  • Presbyterian Kaseman Hospital

    Albuquerque, NM 87110

    Site contact: Kenneth J. Smith · 505-559-6143

  • Mount Kisco Medical Group at Northern Westchester Hospital

    Mount Kisco, NY 10549-3417

    Site contact: Nancy Cohen · 914-242-7649 · NCohen@nwhc.net

  • Health Quest Medical Practice PC-Cardio Thoracic

    Poughkeepsie, NY 12601

    Site contact: Jonathan Clyman · 845-483-6279 · jclyman@Health-quest.org

  • Aultman Health Foundation

    Canton, OH 44710

    Site contact: Shruti Trehan · 330-363-2286 · Shruti.trehan@aultman.com

  • Saint Charles Health System

    Bend, OR 97701

    Site contact: Coralia B. Calomeni · 541-706-5800 · cbcalomeni@stcharleshealthcare.org

  • Paoli Memorial Hospital

    Paoli, PA 19301

    Site contact: Michael B. Dabrow · DabrowM@MLHS.ORG

  • Reading Hospital

    West Reading, PA 19611

    Site contact: Terrence P. Cescon · 484-628-8000 · CesconT@readinghospital.org

  • The Don and Sybil Harrington Cancer Center

    Amarillo, TX 79106

    Site contact: Anita Ravipati · aravipati@harringtoncc.org

  • Doctor's Hospital of Laredo

    Laredo, TX 78041

    Site contact: Gary W. Unzeitig · 956-726-3691 · drgwu@laredobreastcare.com

  • Covenant Medical Center

    Lubbock, TX 79410

    Site contact: Isaac Tafur · 806-725-7993 · oncmd98@yahoo.com

  • Saint Agnes Hospital/Agnesian Cancer Center

    Fond du Lac, WI 54935

    Site contact: Michael W. Jones · 920-926-4100

  • ProHealth Waukesha Memorial Hospital

    Waukesha, WI 53188

    Site contact: Christopher R. Hake · 262-928-5539 · chakemd@gmail.com

  • Cheyenne Regional Medical Center-West

    Cheyenne, WY 82001

    Site contact: Jennifer Van Horn · 307-996-1517 · Jennifer.VanHorn@crmcwy.org

Study contacts (from the official record)

  • Stephen Gruber · sgruber@coh.org
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Molecular Genetics Studies of Cancer Patients and Their Relatives (NCT04185935) | Bored Studies