MOTION Clinical Trial
Moximed · NCT06843980
Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.
Key facts
- Compensation
- Not posted. Ask the study team before screening.
- Who can join
- Any age listed · All sexes
- Healthy volunteers
- Not accepted (a condition is required)
- Study type
- Interventional · Not applicable
- Target enrollment
- 100
- US sites recruiting
- 6
- Study start
- February 13, 2025
- Record last updated
- July 14, 2026
Status re-checked against ClinicalTrials.gov within the last 12 hours.
What the study is about
Prospective, multicenter, two-arm, 2:1 randomized controlled trial (RCT) comparing the benefits in subjects with medial knee osteoarthritis who are treated with either the MISHA Knee System or with non-surgical treatment.
This is the first randomized head-to-head study comparing outcomes from subjects treated with the MISHA Knee System.
Being studied: MISHA Knee System; Non-Surgical Treatment
Conditions: Osteoarthritis, Knee
Eligibility criteria
Copied from the official record. The study team makes the final decision at screening.
Show full criteria
Key Inclusion Criteria
- Activity exacerbated knee pain isolated to the medial compartment and not global in nature
- WOMAC pain ≥ 40
- Failed to find relief in non-surgical treatment modalities
Key Exclusion Criteria
- Large medial osteophyte(s) or considerable extruded meniscus that may interfere with the placement or function of the device
- Poor bone quality (e.g., bony erosion, osteopenia, osteoporosis)
- Ligamentous instability
- Active or recent knee infection
- Inflammatory joint disease, including sequelae of viral infections
- Suspected or documented allergy or hypersensitivity to cobalt, chromium, nickel or other metals
- History of keloid, hypertrophic or contracture scaring
- Propensity for restrictive scar formation or adhesions with prior procedures
Recruiting US locations
Scripps Clinic Jefferson
Oceanside, CA 92054
Site contact: Tianyi Wang, MD
Rush University Medical Center
Chicago, IL 60612
Site contact: Adam Yanke, MD
Genesis Orthopedics & Sports Medicine
Oak Brook, IL 60523
Site contact: Hythem Shadid, MD
University of Nebraska Medical Center
Omaha, NE 68198
Site contact: Matthew Tao, MD
Ohio State Jameson Crane Sports Medicine Institute
Columbus, OH 43202
Site contact: Robert Magnussen, MD
UT Health San Antonio
San Antonio, TX 78249
Site contact: Thomas DeBerardino, MD
Study contacts (from the official record)
- Rose S Weinstein · (510) 887 3375 · rsweinstein@moximed.com
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