Neuroimaging of Opioid Phase (OPAL)
Duke University · with National Institutes of Health (NIH), National Institute on Drug Abuse (NIDA) · NCT05905419
Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.
Key facts
- Compensation
- Not posted. Ask the study team before screening.
- Who can join
- Ages 18+ · Women only
- Healthy volunteers
- Accepted
- Study type
- Interventional · Not applicable
- Target enrollment
- 140
- US sites recruiting
- 1
- Study start
- June 1, 2023
- Record last updated
- June 3, 2026
Status re-checked against ClinicalTrials.gov within the last 12 hours.
What the study is about
The purpose of this study is to compare activity in the brains of female adults with chronic pain and/or opioid use, and healthy female adults that may help to develop new and targeted treatments for adults with chronic pain and alternatives to opioid therapy.
Being studied: Opioid Phase
Conditions: Chronic Pain; Opioid Use
Eligibility criteria
Copied from the official record. The study team makes the final decision at screening.
Show full criteria
Inclusion Criteria for Healthy Controls
- female and ages 18+
- ability to read/understand English and give consent to participate
- no current or history of chronic pain
- not regularly taking any pain-relieving or mood-altering medications (per PI discretion)
- absence of use of opioid medications
Inclusion Criteria for Individuals with Chronic Pain:
- female and ages 18 +
- ability to read/understand English and give consent to participate
- self-reported or physician diagnosis of fibromyalgia and/or chronic pain
- current use of opioid medication(s) for inclusion in the opioid patient group -OR- absence of use of opioid medications for inclusion in the non-opioid patient group
Exclusion Criteria (for both groups):
- limited ability to participate fully in behavioral tasks, longitudinal follow-up
- MRI contraindication
- any factors that at the discretion of the investigators would adversely affect the participant or the integrity of the study
- male
Recruiting US locations
Duke University Medical Center
Durham, NC 27710
Site contact: HAPN Lab Manager · 919-684-2758 · ChronicPainResearch@duke.edu
Study contacts (from the official record)
- HAPN Lab Manager · 919-684-2758 · chronicpainresearch@duke.edu
- Angelina Xiong, BS · 919-684-3136 · angelina.xiong@duke.edu
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