Novel Multimodal Neural, Physiological, and Behavioral Sensing and Machine Learning for Mental States
University of Southern California · with National Institute of Mental Health (NIMH) · NCT07110688
Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.
Key facts
- Compensation
- Not posted. Ask the study team before screening.
- Who can join
- Ages 18+ · All sexes
- Healthy volunteers
- Accepted
- Study type
- Interventional · Not applicable
- Target enrollment
- 90
- US sites recruiting
- 2
- Study start
- August 1, 2024
- Record last updated
- October 1, 2025
Status re-checked against ClinicalTrials.gov within the last 12 hours.
What the study is about
In this program, the investigators will develop novel multimodal neural-behavioral-physiological monitoring tools (software and hardware), and machine learning models for mental states within social processes and beyond. The tools consist of a multimodal skin-like wearable sensor for physiological and biochemical sensing; a conversational virtual human platform to evoke naturalistic social processes; audiovisual affect recognition software; synchronization tools; and machine learning methods to model the multimodal data. The investigators will demonstrate the tools in healthy subjects without neural recordings and in patients with drug-resistant epilepsy who already have intracranial EEG (iEEG) electrodes implanted based on clinical criteria for standard monitoring to localize seizures, which is unrelated to our study.
Being studied: Virtual human social interaction; Cold pressor test
Conditions: No Condition; Study Mental State in Healthy Populations and Drug-resistant Epilepsy Patients With Existing iEEG
Eligibility criteria
Copied from the official record. The study team makes the final decision at screening.
Show full criteria
For the healthy population, all subjects over the age of 18 who are able and willing to give informed consent will be eligible.
For the epilepsy population, inclusion criteria are:
- Patients who suffer from drug-resistant epilepsy and already have intracranial EEG (iEEG) electrodes implanted based on clinical criteria for their standard seizure localization (unrelated to our study) will be eligible. Most patients are healthy adults outside of their epilepsy.
- Subjects >= 18 are only included in this study.
- All patients with the above conditions and with already-implanted electrodes who are willing to participate and able to cooperate and follow research instructions will be recruited.
Recruiting US locations
Rancho Los Amigos National Rehabilitation Center
Downey, CA 90242
Site contact: Charles Liu, MD, PhD · 323-226-7421 · cliu@usc.edu
University of Southern California
Los Angeles, CA 90007
Site contact: Maryam M Shanechi, PhD · 213-740-1377 · shanechi@usc.edu
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