Open Label Study to Investigate the Safety and Efficacy of Ponesimod in Moderate-to-Severe Chronic Plaque Psoriasis
Vanda Pharmaceuticals · NCT07362017
Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.
Key facts
- Compensation
- Not posted. Ask the study team before screening.
- Who can join
- Ages 18–65 · All sexes
- Healthy volunteers
- Not accepted (a condition is required)
- Study type
- Interventional · Phase 3
- Target enrollment
- 300
- US sites recruiting
- 10
- Study start
- February 17, 2026
- Record last updated
- September 22, 2026
Status re-checked against ClinicalTrials.gov within the last 12 hours.
What the study is about
An open label study to investigate the safety and efficacy of ponesimod in participants with moderate-to-severe chronic plaque psoriasis
Being studied: Ponesimod
Conditions: Moderate-to-severe Chronic Plaque Psoriasis
Eligibility criteria
Copied from the official record. The study team makes the final decision at screening.
Show full criteria
Inclusion Criteria
- Male and female subjects aged 18-65 years, inclusive
- BMI >18 and \<40
- Minimum affected BSA of 10%
- PASI score ≥ 12
- PGA ≥ 3
- Diagnosed with moderate-to-severe plaque psoriasis
Exclusion Criteria
- Diagnosis of generalized erythrodermic, generalized pustular (von Zumbusch), guttate, or palmoplantar psoriasis
- History of an allergic reaction or known and/or significant sensitivity to study drug
Recruiting US locations
Vanda Investigational Site
Glendale, AZ 85308
Vanda Investigational Site
Fremont, CA 94538
Vanda Investigational Site
Miami, FL 33126
Vanda Investigational Site
Indianapolis, IN 46250
Vanda Investigational Site
Portsmouth, NH 03801
Vanda Investigational Site
Rochester, NY 14623
Vanda Investigational Site
Wilmington, NC 28405
Vanda Investigational Site
San Antonio, TX 78213
Vanda Investigational Site
Webster, TX 77598
Vanda Investigational Site
Spokane, WA 99202
Study contacts (from the official record)
- Vanda Pharmaceuticals, Inc. · 202-734-3400 · clinicaltrials@vandapharma.com
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