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Testing an Enhanced Digital Delivery Model for Inherited Cancer Genetic Testing in Young Adults With Cancer

Alliance for Clinical Trials in Oncology · with National Cancer Institute (NCI) · NCT07091617

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Opens the official ClinicalTrials.gov record, with the study team’s contacts. Bored Studies doesn’t enroll anyone.

Key facts

Compensation
Not posted. Ask the study team before screening.
Who can join
Ages 18+ · All sexes
Healthy volunteers
Accepted
Study type
Interventional · Not applicable
Target enrollment
535
US sites recruiting
320
Study start
December 10, 2025
Record last updated
October 2, 2026

Status re-checked against ClinicalTrials.gov within the last 12 hours.

What the study is about

This phase III trial compares the use of a digital chatbot enabled intervention to standard remote genetic services for increasing uptake of genetic counseling and testing among adolescents and young adult (AYA) cancer patients. Genetic testing for cancer predisposition syndromes has become standard evidence-based practice and can inform enhanced screening and risk reducing measures to reduce cancer morbidity and mortality. Despite this, many AYAs are not receiving recommended genetic counseling and testing. Offering remote telehealth services can address access barriers and chatbots and texting interventions could enhance patient outcomes and reduce provider and staff time. The use of a digital chatbot enabled intervention may be equally as effective as standard remote genetic services in AYA cancer patients undergoing genetic testing.

Being studied: Telemedicine; Genetic Testing; Telemedicine; Internet-Based Intervention; Educational Intervention; Patient Navigation; Interview; Survey Administration

Conditions: Miscellaneous Neoplasm, Nos; Non-Neoplastic Condition, Nos

Eligibility criteria

Copied from the official record. The study team makes the final decision at screening.

Show full criteria
  • PATIENTS: Age ≥ 18 years and ≤ 39 years at the time of enrollment
  • PATIENTS: AYA cancer patients and survivors. This includes patients at any stage of diagnosis (e.g., newly diagnosed, in treatment, in survivorship) and a cancer diagnosis (including pediatric cancers) at any age ≤ 39 years old. Given targeted therapies for BRCA+ and microsatellite instability (MSI)-high/Lynch Syndrome patients and benefit to relatives, patients with metastatic cancer are included. Any history of cancer, regardless of being in treatment or not
  • PATIENTS: Language: In order to complete the mandatory patient-completed measures and receive genetic education and counseling, participants must be able to speak and read English or Spanish
  • PATIENTS: No known diagnosis of dementia or cognitive impairment. Persons with impaired decision-making capacity are ineligible as they need to be able to understand genetic test results, its implications for the patient and family, and explain genetic test results to their family members
  • PATIENTS: No persons with a known psychiatric or documented developmental disorder that affects cognitive or emotional functions to the extent that the capacity for judgment and reason is significantly diminished, such that they cannot participate based on the judgment of the treating physician
  • PATIENTS: Participants must meet National Comprehensive Cancer Network (NCCN) guidelines for genetic testing assessment provided by Penn Telegenetics by the Eligibility Verification Assessment (EVA) chatbot, or paper forms and genetic counselor's review
  • NON-PATIENT PARTICIPANT: Non-patient participants eligible for this study include: oncology providers, members of the care team and clinic staff, genetic counselors, and insurers (i.e., people who work in financial services and/or for insurance companies) who participate in oncology care among AYA in community for this study
  • NON-PATIENT PARTICIPANT: Age ≥ 18 years
  • NON-PATIENT PARTICIPANT: Non-patient participants must be able to speak and read English or Spanish in order to participate in the key informant interviews

Recruiting US locations

  • Anchorage Associates in Radiation Medicine

    Anchorage, AK 98508

    Site contact: Site Public Contact · 907-212-6871 · AKPAMC.OncologyResearchSupport@providence.org

  • Alaska Breast Care and Surgery LLC

    Anchorage, AK 99508

    Site contact: Site Public Contact · 907-212-6871 · AKPAMC.OncologyResearchSupport@providence.org

  • Alaska Oncology and Hematology LLC

    Anchorage, AK 99508

    Site contact: Site Public Contact · 907-212-6871 · AKPAMC.OncologyResearchSupport@providence.org

  • Alaska Women's Cancer Care

    Anchorage, AK 99508

    Site contact: Site Public Contact · 907-212-6871 · AKPAMC.OncologyResearchSupport@providence.org

  • Katmai Oncology Group

    Anchorage, AK 99508

    Site contact: Site Public Contact · 907-212-6871 · AKPAMC.OncologyResearchSupport@providence.org

  • Providence Alaska Medical Center

    Anchorage, AK 99508

    Site contact: Site Public Contact · 907-212-6871 · AKPAMC.OncologyResearchSupport@providence.org

  • Fairbanks Memorial Hospital

    Fairbanks, AK 99701

    Site contact: Site Public Contact · 907-458-3043 · Veronica.Stevenson@foundationhealth.org

  • Cancer Center at Saint Joseph's

    Phoenix, AZ 85004

    Site contact: Site Public Contact · 720-874-1881 · ResearchInstituteInquiries@CommonSpirit.org

  • Mercy Hospital Fort Smith

    Fort Smith, AR 72903

    Site contact: Site Public Contact · 800-378-9373

  • CARTI Cancer Center

    Little Rock, AR 72205

    Site contact: Site Public Contact · 501-906-4199 · Research@CARTI.com

  • Mission Hope Medical Oncology - Arroyo Grande

    Arroyo Grande, CA 93420

    Site contact: Site Public Contact · 720-874-1881 · ResearchInstituteInquiries@CommonSpirit.org

  • Providence Saint Joseph Medical Center/Disney Family Cancer Center

    Burbank, CA 91505

    Site contact: Site Public Contact · 818-847-4793 · Najee.Boucher@providence.org

  • Mercy Cancer Center - Carmichael

    Carmichael, CA 95608

    Site contact: Site Public Contact · 720-874-1881 · ResearchInstituteInquiries@CommonSpirit.org

  • Mercy San Juan Medical Center

    Carmichael, CA 95608

    Site contact: Site Public Contact · 720-874-1881 · ResearchInstituteInquiries@commonspirit.org

  • Mercy Cancer Center - Elk Grove

    Elk Grove, CA 95758

    Site contact: Site Public Contact · 720-874-1881 · ResearchInstituteInquiries@CommonSpirit.org

  • Mercy Cancer Center

    Merced, CA 95340

    Site contact: Site Public Contact · 720-874-1881 · ResearchInstituteInquiries@CommonSpirit.org

  • Providence Queen of The Valley

    Napa, CA 94558

    Site contact: Site Public Contact · 707-521-3830

  • Mercy Cancer Center - Rocklin

    Rocklin, CA 95765

    Site contact: Site Public Contact · 720-874-1881 · ResearchInstituteInquiries@CommonSpirit.org

  • Mercy Cancer Center - Sacramento

    Sacramento, CA 95816

    Site contact: Site Public Contact · 720-874-1881 · ResearchInstituteInquiries@CommonSpirit.org

  • Pacific Central Coast Health Center-San Luis Obispo

    San Luis Obispo, CA 93401

    Site contact: Site Public Contact · 720-874-1881 · ResearchInstituteInquiries@CommonSpirit.org

  • Mission Hope Medical Oncology - Santa Maria

    Santa Maria, CA 93444

    Site contact: Site Public Contact · 720-874-1881 · ResearchInstituteInquiries@CommonSpirit.org

  • Providence Medical Foundation - Santa Rosa

    Santa Rosa, CA 95403

    Site contact: Site Public Contact · 707-521-3830

  • Providence Santa Rosa Memorial Hospital

    Santa Rosa, CA 95405

    Site contact: Site Public Contact · 707-521-3830

  • Saint Joseph's Medical Center

    Stockton, CA 95204

    Site contact: Site Public Contact · 209-461-5257

  • Woodland Memorial Hospital

    Woodland, CA 95695

    Site contact: Site Public Contact · 720-874-1881 · ResearchInstituteInquiries@CommonSpirit.org

  • Penrose-Saint Francis Healthcare

    Colorado Springs, CO 80907

    Site contact: Site Public Contact · 720-874-1881 · ResearchInstituteInquiries@CommonSpirit.org

  • Rocky Mountain Cancer Centers-Penrose

    Colorado Springs, CO 80907

    Site contact: Site Public Contact · 720-874-1881 · ResearchInstituteInquiries@CommonSpirit.org

  • Saint Francis Cancer Center

    Colorado Springs, CO 80923

    Site contact: Site Public Contact · 720-874-1881 · ResearchInstituteInquiries@CommonSpirit.org

  • CommonSpirit Cancer Center Mercy

    Durango, CO 81301

    Site contact: Site Public Contact · 720-874-1881 · ResearchInstituteInquiries@CommonSpirit.org

  • Mercy Medical Center

    Durango, CO 81301

    Site contact: Site Public Contact · 720-874-1881 · ResearchInstituteInquiries@CommonSpirit.org

  • CommonSpirit Saint Anthony Hospital Cancer Center

    Lakewood, CO 80228

    Site contact: Site Public Contact · 720-874-1881 · ResearchInstituteInquiries@CommonSpirit.org

  • Longmont United Hospital

    Longmont, CO 80501

    Site contact: Site Public Contact · 720-874-1881 · ResearchInstituteInquiries@CommonSpirit.org

  • Saint Mary Corwin Medical Center

    Pueblo, CO 81004

    Site contact: Site Public Contact · 720-874-1881 · ResearchInstituteInquiries@CommonSpirit.org

  • Saint Anthony North Hospital

    Westminster, CO 80023

    Site contact: Site Public Contact · 720-874-1881 · ResearchInstituteInquiries@CommonSpirit.org

  • Alfred I duPont Hospital for Children

    Wilmington, DE 19803

    Site contact: Site Public Contact · 302-651-5572 · Allison.bruce@nemours.org

  • Holy Cross Hospital

    Fort Lauderdale, FL 33308

    Site contact: Site Public Contact · eileen.georgi@holy-cross.com

  • Arnold Palmer Hospital for Children

    Orlando, FL 32806

    Site contact: Site Public Contact · 321-841-5357 · Jennifer.spinelli@orlandohealth.com

  • Nemours Children's Hospital

    Orlando, FL 32827

    Site contact: Site Public Contact · 302-651-5572 · Allison.bruce@nemours.org

  • Nemours Children's Clinic - Pensacola

    Pensacola, FL 32504

    Site contact: Site Public Contact · 888-823-5923 · ctsucontact@westat.com

  • Augusta University Medical Center

    Augusta, GA 30912

    Site contact: Site Public Contact · 706-721-2388 · ga_cares@augusta.edu

  • Kapiolani Medical Center for Women and Children

    Honolulu, HI 96826

    Site contact: Site Public Contact · 808-983-6090

  • Saint Alphonsus Cancer Care Center-Boise

    Boise, ID 83706

    Site contact: Site Public Contact · 734-712-3671 · stephanie.couch@stjoeshealth.org

  • Saint Luke's Cancer Institute - Boise

    Boise, ID 83712

    Site contact: Site Public Contact · 208-381-2774 · eslinget@slhs.org

  • Saint Alphonsus Cancer Care Center-Caldwell

    Caldwell, ID 83605

    Site contact: Site Public Contact · 734-712-3671 · stephanie.couch@stjoeshealth.org

  • Kootenai Health - Coeur d'Alene

    Coeur d'Alene, ID 83814

    Site contact: Site Public Contact · 406-969-6060 · mccinfo@mtcancer.org

  • Saint Luke's Cancer Institute - Fruitland

    Fruitland, ID 83619

    Site contact: Site Public Contact · 208-381-2774 · eslinget@slhs.org

  • Idaho Urologic Institute-Meridian

    Meridian, ID 83642

    Site contact: Site Public Contact · 734-712-3671 · stephanie.couch@stjoeshealth.org

  • Saint Luke's Cancer Institute - Meridian

    Meridian, ID 83642

    Site contact: Site Public Contact · 208-381-2774 · eslinget@slhs.org

  • Saint Alphonsus Cancer Care Center-Nampa

    Nampa, ID 83687

    Site contact: Site Public Contact · 406-969-6060 · mccinfo@mtcancer.org

  • Saint Luke's Cancer Institute - Nampa

    Nampa, ID 83687

    Site contact: Site Public Contact · 208-381-2774 · eslinget@slhs.org

  • Kootenai Clinic Cancer Services - Post Falls

    Post Falls, ID 83854

    Site contact: Site Public Contact · 406-969-6060 · mccinfo@mtcancer.org

  • Kootenai Clinic Cancer Services - Sandpoint

    Sandpoint, ID 83864

    Site contact: Site Public Contact · 406-969-6060 · mccinfo@mtcancer.org

  • Saint Luke's Cancer Institute - Twin Falls

    Twin Falls, ID 83301

    Site contact: Site Public Contact · 208-381-2774 · eslinget@slhs.org

  • OSF Saint Anthony's Health Center

    Alton, IL 62002

    Site contact: Site Public Contact · 618-463-5623

  • Advocate Outpatient Center - Aurora

    Aurora, IL 60506

    Site contact: Site Public Contact · ncorp@aah.org

  • Advocate Good Shepherd Hospital

    Barrington, IL 60010

    Site contact: Site Public Contact · 847-842-4847

  • Illinois CancerCare-Bloomington

    Bloomington, IL 61704

    Site contact: Site Public Contact · 309-243-3605 · andersonj@illinoiscancercare.com

  • Illinois CancerCare-Canton

    Canton, IL 61520

    Site contact: Site Public Contact · 309-243-3605 · andersonj@illinoiscancercare.com

  • Memorial Hospital of Carbondale

    Carbondale, IL 62902

    Site contact: Site Public Contact · 618-457-5200 · clinical.research@sih.net

  • SIH Cancer Institute

    Carterville, IL 62918

    Site contact: Site Public Contact · 618-985-3333 · clinical.research@sih.net

+ 260 more on the official record.

Study contacts (from the official record)

  • Rachel Wills · 773-702-9171 · cancercontrolprotocols@alliancenctn.org
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Testing an Enhanced Digital Delivery Model for Inherited Cancer… (NCT07091617) | Bored Studies