Location · Massachusetts
Clinical trials recruiting in Massachusetts
886 recruiting studies have at least one site in Massachusetts; 358 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in Massachusetts.
886 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 3
Cantharidin Application in Patients With Common Warts (Verruca Vulgaris) (COVE-3)
Verrica Pharmaceuticals Inc.
- Location
- Brighton, MA + 5 other US sites
- Eligibility basics
- Ages 2+
- RecruitingPhase 2
A Study to Investigate the Efficacy, Safety, and Tolerability of AZD4144in Participants With Sepsis-associated Acute Kidney Injury.
AstraZeneca
- Location
- Boston, MA + 7 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 2
A Study of Mosliciguat in Combination With Inhaled Treprostinil in PH-ILD
Pulmovant, Inc.
- Location
- Boston, MA + 12 other US sites
- Eligibility basics
- Ages 18–85
- RecruitingPhase 3
An Adaptive Program of IKT-001 in Pulmonary Arterial Hypertension (PAH)
Inhibikase Therapeutics
- Location
- Boston, MA + 14 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
A Safety, Tolerability, and Efficacy Study of VX-880 and VX-017 in Participants With Type 1 Diabetes
Vertex Pharmaceuticals Incorporated
- Location
- Boston, MA + 9 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 2
Usnoflast Neuromuscular Investigation for Treatment Efficacy in Amyotrophic Lateral Sclerosis
Zydus Therapeutics Inc.
- Location
- Boston, MA + 13 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2/Phase 3
Open Label, Safety and Efficacy Study of QRX003 Lotion in Subjects With Netherton Syndrome
Quoin Pharmaceuticals
- Location
- Quincy, MA + 2 other US sites
- Eligibility basics
- Ages 14+
- RecruitingPhase 1/Phase 2
Study of CTO1681 for the Prevention and Treatment of CRS in Patients Receiving CAR T-Cell Therapy
CytoAgents, Inc.
- Location
- Boston, MA + 5 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2/Phase 3
Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)
Merck Sharp & Dohme LLC
- Location
- Boston, MA + 19 other US sites
- Eligibility basics
- Ages 1 mo–17
- RecruitingPhase 1/Phase 2
Phase I/II Study of SKG0106 Intravitreal Injection in Patients With Neovascular Age-related Macular Degeneration (nAMD)
Skyline Therapeutics (US) Inc.
- Location
- Boston, MA + 2 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 1/Phase 2
ALXN2350 in Adult Participants With BAG3-Associated Dilated Cardiomyopathy
Alexion Pharmaceuticals, Inc.
- Location
- Boston, MA + 6 other US sites
- Eligibility basics
- Ages 18–70
- Recruiting
The Golazo® Peripheral Atherectomy System for a Safe and Effective Atherectomy (GREAT Trial)
Nipro Vascular Innovations Americas, Inc
- Location
- Plymouth, MA + 16 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
AMBER-HFpEF: Assessment of CK-4021586 in a Multi-Center, Blinded Evaluation of Safety and Tolerability Results in HFpEF
Cytokinetics
- Location
- Boston, MA + 23 other US sites
- Eligibility basics
- Ages 40–85
- RecruitingPhase 1/Phase 2
Open-label Study of SKY-GJB2 in Pediatric Subjects With GJB2-mediated Hearing Loss
Skylark Bio Inc.
- Location
- Boston, MA + 3 other US sites
- Eligibility basics
- Ages 10 mo–7
- RecruitingPhase 3
Efficacy and Safety of Remibrutinib After Switching From Ocrelizumab in Participants Living With Relapsing Multiple Sclerosis.
Novartis Pharmaceuticals
- Location
- Burlington, MA + 42 other US sites
- Eligibility basics
- Ages 40–70
- RecruitingPhase 2
A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease
Immunovant Sciences GmbH
- Location
- Boston, MA + 54 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2
A Phase 2 Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, in Adults and Children With PIK3CA Related Overgrowth Spectrum and Malformations Driven by PIK3CA Mutation (The ReInspire Study)
Relay Therapeutics, Inc.
- Location
- Boston, MA + 21 other US sites
- Eligibility basics
- Ages 2+
- RecruitingPhase 1/Phase 2
AMT-260 Gene Therapy Study in Adults With Unilateral Refractory Mesial Temporal Lobe Epilepsy
UniQure Biopharma B.V.
- Location
- Boston, MA + 15 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1
Phase 1 Study to Evaluate Safety and Antiviral Activity of PBGENE-HBV in Adult Patients With Chronic Hepatitis B
Precision BioSciences, Inc.
- Location
- Boston, MA
- Eligibility basics
- Ages 18–70
- RecruitingPhase 1/Phase 2
4D-150 in Patients With Neovascular (Wet) Age-Related Macular Degeneration
4D Molecular Therapeutics
- Location
- Boston, MA + 19 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 1/Phase 2
Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Adults With Moderate to Severe Acne
Sanofi Pasteur, a Sanofi Company
- Location
- Brighton, MA + 78 other US sites
- Eligibility basics
- Ages 18–45
- RecruitingPhase 3
A Study to Evaluate the Efficacy and Safety of Elismetrep (K-304) in the Acute Treatment of Migraine
Kallyope Inc.
- Location
- Boston, MA + 111 other US sites
- Eligibility basics
- Ages 18–75
- Recruiting
Carotid Implants for PreveNtion of STrokE ReCurrEnce From Large Vessel Occlusion in Atrial Fibrillation Patients Treated With Oral Anticoagulation
Javelin Medical
- Location
- Boston, MA + 3 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Study of an Intrathecal Port and Catheter System for Subjects With Spinal Muscular Atrophy
Alcyone Therapeutics, Inc
- Location
- Boston, MA + 14 other US sites
- Eligibility basics
- Ages 3+