Location · Massachusetts
Clinical trials recruiting in Massachusetts
886 recruiting studies have at least one site in Massachusetts; 358 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in Massachusetts.
886 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 2
JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort A: Vilobelimab
PPD Development, LP
- Location
- Burlington, MA + 27 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS (Master Record)
PPD Development, LP
- Location
- Burlington, MA + 26 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
GORE® CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients With Patent Foramen Ovale (PFO): the REDUCE Post Approval Study
W.L.Gore & Associates
- Location
- Boston, MA + 30 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 3
Study to Assess the Efficacy and Safety of IMVT-1402 in Participants With Mild to Severe Generalized Myasthenia Gravis
Immunovant Sciences GmbH
- Location
- Foxborough, MA + 47 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 3
Elucidating TAAR-1, Dopamine, and Norepinephrine in Binge Eating Disorder Using Solriamfetol
Axsome Therapeutics, Inc.
- Location
- Boston, MA + 35 other US sites
- Eligibility basics
- Ages 18–55
- RecruitingPhase 2
Phase 2b Study of RPT904 as Monotherapy in Participants With IgE-Mediated Food Allergy
RAPT Therapeutics, Inc., a member of the GSK plc group of companies
- Location
- Boston, MA + 21 other US sites
- Eligibility basics
- Ages 12–55
- RecruitingPhase 2
Tacrolimus Ophthalmic Solution for the Treatment of Non-infectious Anterior Uveitis
Novaliq GmbH
- Location
- Waltham, MA + 5 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Phase 2 Study of Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder
Syndeio Biosciences, Inc
- Location
- Worcester, MA + 22 other US sites
- Eligibility basics
- Ages 18–64
- Recruiting
Early Feasibility Study (EFS) Evaluating Percutaneous Repair of the Atrial Septum With a Novel PFO Occluder: The PROTEA-PFO Study
Recross Cardio, Inc.
- Location
- Boston, MA + 4 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 3
Studying Solriamfetol Modulation of TAAR-1, Dopamine, and Norepinephrine in Shift Work Disorder (SUSTAIN)
Axsome Therapeutics, Inc.
- Location
- Boston, MA + 37 other US sites
- Eligibility basics
- Ages 18–65
- Recruiting
Safety and Effectiveness of the Orsiro Mission 48-mm Sirolimus Eluting Coronary Stent System in Subjects With Coronary Artery Lesions
Teleflex
- Location
- Boston, MA + 9 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
Neurocrine Biosciences
- Location
- Boston, MA + 38 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
A Phase 1/2 Study of the Safety and Efficacy of MVX-220 in Angelman Syndrome
MavriX Bio, LLC
- Location
- Boston, MA + 2 other US sites
- Eligibility basics
- Ages 4–50
- Recruiting
COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve Dysfunction
Edwards Lifesciences
- Location
- Boston, MA + 20 other US sites
- Eligibility basics
- Any age listed
- RecruitingPhase 2
A Study to Assess NAV-240 in Adult Participants With Hidradenitis Suppurativa
Navigator Medicines, Inc.
- Location
- Boston, MA + 13 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 1
Assessing the Safety, Tolerability, and Efficacy of APR-2020 in Pediatric and Adolescent Subjects With RPS19 Deficient Diamond-Blackfan Anemia
Apriligen, Inc.
- Location
- Boston, MA + 1 other US site
- Eligibility basics
- Ages 2–25
- RecruitingPhase 3
Evaluation of Efficacy and Safety of Suzetrigine (SUZ) for Pain Associated With Diabetic Peripheral Neuropathy
Vertex Pharmaceuticals Incorporated
- Location
- Boston, MA + 69 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 3
Beeline: A Phase 3 Study in GRIN-related Neurodevelopmental Disorder
GRIN Therapeutics, Inc.
- Location
- Boston, MA + 15 other US sites
- Eligibility basics
- Ages 1 mo–18
- RecruitingPhase 3
Open-label Extension Study to Evaluate Metreleptin in Patients With Partial Lipodystrophy
Chiesi Farmaceutici S.p.A.
- Location
- Boston, MA + 6 other US sites
- Eligibility basics
- Ages 13+
- Recruiting
The RAPID - PE Study: RESCUE Advanced Protocol for the Treatment of Pulmonary Embolism
Thrombolex, Inc.
- Location
- Boston, MA + 22 other US sites
- Eligibility basics
- Any age listed
- Recruiting
Post Market Study for VasQ, an External Support Implant for Arteriovenous Fistula
Laminate Medical Technologies
- Location
- Boston, MA + 7 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 1
A Study of Healthy Donor CD19-targeted Allogeneic CAR T Cells in Participants With Severe, Refractory Autoimmune Diseases
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company
- Location
- Boston, MA + 1 other US site
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)
Anthos Therapeutics, Inc.
- Location
- Boston, MA + 131 other US sites
- Eligibility basics
- Ages 65+
- RecruitingPhase 3
Study of Efficacy and Safety of Iptacopan in Participants With IC-MPGN
Novartis Pharmaceuticals
- Location
- Boston, MA + 21 other US sites
- Eligibility basics
- Ages 12–60