Location · Massachusetts
Clinical trials recruiting in Massachusetts
886 recruiting studies have at least one site in Massachusetts; 358 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in Massachusetts.
886 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- Recruiting
Access Cannulation Trial II
Voyager Biomedical
- Location
- Boston, MA + 7 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
Neurocrine Biosciences
- Location
- Boston, MA + 12 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Fontan Udenafil Exercise Longitudinal Assessment Trial - 2
Mezzion Pharma Co. Ltd
- Location
- Boston, MA + 34 other US sites
- Eligibility basics
- Ages 12–18
- RecruitingPhase 1/Phase 2
Safety and Feasibility of a Self-Balancing Exoskeleton for Rehabilitation in the Thoracic Surgical Intensive Care Unit: a Pilot Trial
Wandercraft
- Location
- Boston, MA
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Oral Pyridoxal 5'-Phosphate for the Treatment of Patients With PNPO Deficiency
Medicure
- Location
- Boston, MA + 4 other US sites
- Eligibility basics
- Any age listed
- Recruiting
Treatment of Pulmonary Arterial Hypertension Using the Aria CV Pulmonary Hypertension System
Aria CV, Inc
- Location
- Boston, MA + 8 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Study of Navtemadlin add-on to Ruxolitinib in JAK Inhibitor-Naïve Patients With Myelofibrosis Who Have a Suboptimal Response to Ruxolitinib
Kartos Therapeutics, Inc.
- Location
- Boston, MA + 57 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Efficacy and Safety of Masitinib Versus Placebo in the Treatment of ALS Patients
AB Science
- Location
- Burlington, MA + 5 other US sites
- Eligibility basics
- Ages 18–81
- Recruiting
GEnetic Testing in Elective Single Embryo Transfer (GETSET): A Randomized Clinical Trial
Genomic Prediction Inc.
- Location
- Waltham, MA
- Eligibility basics
- Ages 35–40 · Women only
- Recruiting
Smartphone Services for Stimulant Use Disorder
DynamiCare Health
- Location
- Boston, MA
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Paclitaxel Coated Balloon for the Treatment of Chronic bEnigN sTricture- Esophagus
GIE Medical
- Location
- Boston, MA + 32 other US sites
- Eligibility basics
- Ages 22+
- RecruitingPhase 3
Paclitaxel Coated Balloon for the Treatment of Chronic bEnigN sTricture- Bowel
GIE Medical
- Location
- Boston, MA + 30 other US sites
- Eligibility basics
- Ages 22+
- RecruitingPhase 2
Nasal Foralumab in Patients With Non-Active Secondary Progressive Multiple Sclerosis
Tiziana Life Sciences LTD
- Location
- Boston, MA
- Eligibility basics
- Ages 18–75
- Recruiting
A Multi-center, National, Open-label, Prospective Study to Evaluate the Performance of the V-Lap™ System
Vectorious Medical Technologies Ltd.
- Location
- Boston, MA
- Eligibility basics
- Ages 22–88
- RecruitingPhase 1/Phase 2
A Phase 1/2, First-in-Human Dose Escalation/Expansion Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of a Subretinal Injection of SB-007 in Subjects With Stargardt Disease (STGD1)
Splice Bio
- Location
- Boston, MA + 4 other US sites
- Eligibility basics
- Ages 12–65
- RecruitingPhase 1
Study of APG-2575 as a Single Agent or in Combination With Other Therapeutic Agents for CLL/SLL
Ascentage Pharma Group Inc.
- Location
- Boston, MA + 6 other US sites
- Eligibility basics
- Ages 18–85
- RecruitingPhase 2
Trial of the Impact of Sibeprenlimab on Immunoglobulin A Nephropathy Kidney Tissue
Otsuka Pharmaceutical Development & Commercialization, Inc.
- Location
- Boston, MA + 3 other US sites
- Eligibility basics
- Ages 16+
- Recruiting
An Early Feasibility Study of the HighLife 28mm Trans-Septal Transcatheter Mitral Valve Replacement System
HighLife SAS
- Location
- Boston, MA + 7 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
Open-label, Dose Escalation Study of Safety and Preliminary Efficacy of TN-401 in Adults With PKP2 Mutation-associated ARVC
Tenaya Therapeutics
- Location
- Boston, MA + 6 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 4
A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms
Axsome Therapeutics, Inc.
- Location
- Boston, MA + 36 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 2
A Study of NST-6179 in Subjects With Intestinal Failure-Associated Liver Disease (IFALD).
NorthSea Therapeutics B.V.
- Location
- Boston, MA + 11 other US sites
- Eligibility basics
- Ages 16+
- Recruiting
Multicenter Clinical Study of the SING-IMT in Patients with Late-stage AMD
VisionCare, Inc.
- Location
- Lawrence, MA + 9 other US sites
- Eligibility basics
- Ages 65+
- RecruitingPhase 1/Phase 2
A Phase 1/2 Trial of SP-101 for the Treatment of Cystic Fibrosis (CF)
Spirovant Sciences, Inc.
- Location
- Boston, MA + 3 other US sites
- Eligibility basics
- Ages 18–65
- Recruiting
MASA Valve Early Feasibility Study
PECA Labs
- Location
- Boston, MA + 4 other US sites
- Eligibility basics
- Ages 0 mo–22