Location · Massachusetts
Clinical trials recruiting in Massachusetts
886 recruiting studies have at least one site in Massachusetts; 358 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in Massachusetts.
886 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteersPhase 3
A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)
Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics
- Location
- Methuen, MA + 55 other US sites
- Eligibility basics
- Ages 18–79
- RecruitingHealthy volunteersPhase 3
A Phase 3 Study of Revaccination in Subsequent Pregnancies With Bivalent RSV Vaccine and Duration of Protection of a Single Dose
Pfizer
- Location
- Boston, MA + 76 other US sites
- Eligibility basics
- Ages 0 mo+
- RecruitingHealthy volunteersPhase 3
A Study to Learn About a Clostridioides Difficile Vaccine in People 65 Years of Age and Older
Pfizer
- Location
- West Roxbury, MA + 138 other US sites
- Eligibility basics
- Ages 65+
- RecruitingHealthy volunteers
Observational Study of Decentralized Urine Optical Interaction Patterns Associated With Environmental Microplastic and Nanoplastic Exposure
Ecotera Health LLC
- Location
- Boston, MA + 50 other US sites
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events
Cleerly, Inc.
- Location
- Boston, MA + 121 other US sites
- Eligibility basics
- Ages 55+
- RecruitingHealthy volunteersPhase 3
BEATRIX: A Study to Learn About a Group B Streptococcus Vaccine in Healthy Pregnant Women and Their Babies
Pfizer
- Location
- Boston, MA + 111 other US sites
- Eligibility basics
- Ages 0 mo–49
- RecruitingHealthy volunteersPhase 3
A Study on the Efficacy of a Vaccine Against Influenza in Adults ≥65 Years of Age
GlaxoSmithKline
- Location
- Boston, MA + 130 other US sites
- Eligibility basics
- Ages 65+
- RecruitingHealthy volunteers
Making Connections Thru Music
Hopeful Aging
- Location
- Winchester, MA + 1 other US site
- Eligibility basics
- Ages 18–103
- RecruitingHealthy volunteers
AVAVA MIRIA General Use
AVAVA, Inc.
- Location
- Waltham, MA
- Eligibility basics
- Ages 18–70
- RecruitingHealthy volunteersPhase 3
A Study to Learn About the Safety of an Expanded Pneumococcal Vaccine in Healthy Infants
Pfizer
- Location
- Fall River, MA + 20 other US sites
- Eligibility basics
- Ages 1 mo–4 mo
- RecruitingHealthy volunteersPhase 3
Study to Learn About Safety, Tolerability, and Immune Response of a Catch-up Pneumococcal Vaccine in Children and Adolescents
Pfizer
- Location
- Fall River, MA + 49 other US sites
- Eligibility basics
- Ages 1–17
- RecruitingHealthy volunteers
A Prospective Controlled Study to Evaluate the Safety and Effectiveness of Thermage® FLX Radiofrequency Treatment
Bausch Health Americas, Inc.
- Location
- Chestnut Hill, MA + 5 other US sites
- Eligibility basics
- Ages 30–60
- RecruitingHealthy volunteers
Safety and Effectiveness of Mosaic for the Treatment of Midface Volume Deficit
Helios Aesthetics Inc.
- Location
- Chestnut Hill, MA + 4 other US sites
- Eligibility basics
- Ages 22+
- RecruitingHealthy volunteers
Brain Stimulation Paired With Structured Language Learning in Adults
General Neuro Inc.
- Location
- Boston, MA
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Aptis PRUJ Prosthesis for the Treatment of Patients With Proximal Radial Ulna Joint Disorders.
Aptis Medical
- Location
- Boston, MA + 5 other US sites
- Eligibility basics
- Ages 18–85
- RecruitingHealthy volunteersPhase 3
A Study on the Immune Response and Safety of an Investigational Chickenpox Vaccine When Given to Healthy Children 12 to 15 Months of Age
GlaxoSmithKline
- Location
- Fall River, MA + 46 other US sites
- Eligibility basics
- Ages 1–1
- RecruitingHealthy volunteers
mTBI Identification and Monitoring Through Retinal Scanning
Rebiscan, Inc.
- Location
- Boston, MA
- Eligibility basics
- Ages 18–45
- RecruitingHealthy volunteersPhase 3
A Study to Learn About the Safety, Tolerability, and Immunogenicity of a Fifth Dose of 6-Valent OspA-Based Lyme Disease Vaccine
Pfizer
- Location
- Worcester, MA + 10 other US sites
- Eligibility basics
- Ages 7+
- RecruitingHealthy volunteers
Direct to Patient Minimal Risk Biospecimen and Data Collection Research
Joined Bio
- Location
- Lexington, MA
- Eligibility basics
- Ages 18–90
- RecruitingHealthy volunteersPhase 3
REVEAL Study - Diagnostic Testing for PTSD Using the Senseye Diagnostic Tool
Senseye, Inc.
- Location
- Boston, MA + 2 other US sites
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Comparison of the Effects of Oral Hygiene Regimens on Clinical, Immunomodulatory, and Microbial Outcomes and Oral Tolerance in People With Gingivitis
Kenvue Brands LLC
- Location
- Somerville, MA
- Eligibility basics
- Ages 18–60
- RecruitingHealthy volunteers
Efficacy in Controlling Myopia in Young Children Using a Novel Spectacle Lens
SightGlass Vision, Inc.
- Location
- Boston, MA + 13 other US sites
- Eligibility basics
- Ages 6–8
- RecruitingHealthy volunteersPhase 2
Topical Tolnaftate Stick for Tinea Pedis: An Open-Label Interventional Study
Propedix, Inc.
- Location
- Framingham, MA + 1 other US site
- Eligibility basics
- Ages 16+
- RecruitingHealthy volunteers
US Benchmarking Clinical Study
eMyosound SAS
- Location
- Boston, MA + 2 other US sites
- Eligibility basics
- Ages 60+