Location · Ohio
Clinical trials recruiting in Ohio
965 recruiting studies have at least one site in Ohio; 272 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in Ohio.
965 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
More recruiting studies (pay not posted)
- RecruitingPhase 3
A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure
AstraZeneca
- Location
- Canton, OH + 104 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Comparing The Safety And Efficacy Of DEFENCATH® In Reducing Central-Line Bloodstream Infections (CLABSIs) In Adults And Adolescent Participants Receiving Total Parenteral Nutrition Through A Central Venous Catheter (CVC)
CorMedix Therapeutics
- Location
- Cleveland, OH + 16 other US sites
- Eligibility basics
- Ages 12+
- RecruitingPhase 2
Dose Range Finding Study to Assess Efficacy and Safety of Tozorakimab in Adults With Uncontrolled Asthma on Medium-to-High Dose Inhaled Corticosteroids
AstraZeneca
- Location
- Toledo, OH + 21 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 4
Phase 4 Study: Long-term Safety and Efficacy of NT-501 in MacTel Type 2, Including Sham Procedure Participants
Neurotech Pharmaceuticals
- Location
- Cincinnati, OH + 15 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
NBI-1117568-SCZ3030: Evaluation of NBI-1117568 in Inpatient Adults With Schizophrenia
Neurocrine Biosciences
- Location
- North Canton, OH + 5 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 3
NBI-1117568-SCZ3032: Long-Term Evaluation of NBI-1117568 in Adults With Schizophrenia
Neurocrine Biosciences
- Location
- North Canton, OH + 44 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 3
A Study to Evaluate the Efficacy and Safety of Esketamine for Reduction of Symptoms of Major Depressive Disorder
Janssen Research & Development, LLC
- Location
- Cincinnati, OH + 9 other US sites
- Eligibility basics
- Ages 12–17
- RecruitingPhase 2
Study of ENV-294 in Adults With Moderate-to-Severe Atopic Dermatitis
Enveda Therapeutics
- Location
- Canton, OH + 29 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2
Study of REGN13335 in Adult Participants With Pulmonary Arterial Hypertension (PAH)
Regeneron Pharmaceuticals
- Location
- Cincinnati, OH + 3 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study to Evaluate the Efficacy and Safety of JNJ-88545223 for the Treatment of Participants With Active Psoriatic Arthritis
Janssen Research & Development, LLC
- Location
- Middleburg Heights, OH + 17 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Transcatheter Tricuspid Valve Replacement With the Medtronic Intrepid™ Transcatheter Tricuspid Valve Replacement (TTVR) System in Severe Tricuspid Regurgitation
Medtronic Cardiovascular
- Location
- Cincinnati, OH + 12 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study of Nipocalimab in Adults With Moderate to Severe Systemic Lupus Erythematosus
Janssen Research & Development, LLC
- Location
- Middleburg Heights, OH + 37 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
A Study of Guselkumab Versus Risankizumab in Participants With Moderately to Severely Active Crohn's Disease
Janssen Research & Development, LLC
- Location
- Mentor, OH + 35 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Phase 2a Study of SUN-627 in Participants With Non-Active Secondary Progressive and Primary Progressive Multiple Sclerosis (SPMS/PPMS)
Sundance Biosciences, Inc.
- Location
- Columbus, OH + 2 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 3
Randomized Study in Children and Adolescents With Migraine: Acute Treatment
Pfizer
- Location
- Cincinnati, OH + 69 other US sites
- Eligibility basics
- Ages 6–17
- RecruitingPhase 3
Long-term Safety Study of Rimegepant in Pediatric Subjects for the Acute Treatment of Migraine
Pfizer
- Location
- Cincinnati, OH + 54 other US sites
- Eligibility basics
- Ages 6–17
- Recruiting
ALLIANCE: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve
Edwards Lifesciences
- Location
- Cincinnati, OH + 30 other US sites
- Eligibility basics
- Any age listed
- RecruitingPhase 1/Phase 2
Safety, PK/PD, and Exploratory Efficacy Study of AMT-191 in Classic Fabry Disease
UniQure Biopharma B.V.
- Location
- Cincinnati, OH + 9 other US sites
- Eligibility basics
- Ages 18–65 · Men only
- RecruitingPhase 3
A Study to Investigate the Efficacy and Safety of Anifrolumab Administered as Subcutaneous Injection and Added to Standard of Care Compared With Placebo Added to Standard of Care in Adult Participants With Idiopathic…
AstraZeneca
- Location
- Cleveland, OH + 31 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
Evaluation of Efficacy and Safety of Milsaperidone as Adjunctive Therapy in Patients With Major Depressive Disorder
Vanda Pharmaceuticals
- Location
- Cincinnati, OH + 24 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 1
A Study of SGT-501 Gene Therapy in Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)
Solid Biosciences Inc.
- Location
- Cleveland, OH + 2 other US sites
- Eligibility basics
- Ages 7+
- RecruitingPhase 3
Assessing the Impact of Muvalaplin on Major Cardiovascular Events in Adults With Elevated Lipoprotein(a)
Eli Lilly and Company
- Location
- Cincinnati, OH + 120 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
Safety and Tolerability of Subretinally Injected OPGx-BEST1 in Patients With Best Vitelliform Macular Dystrophy (BVMD) or Autosomal-Recessive Bestrophinopathy (ARB)
Opus Genetics, Inc
- Location
- Cincinnati, OH + 3 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
ADAPT Forward 1 - ISA1 - a Study to Evaluate Empasiprubart IV as add-on Therapy to Efgartigimod IV in Participants With AChR-Ab Seropositive Generalized Myasthenia Gravis With a Partial Clinical Response to Efgartigimod
argenx
- Location
- Cincinnati, OH + 13 other US sites
- Eligibility basics
- Ages 18+