Location · Pennsylvania
Clinical trials recruiting in Pennsylvania
943 recruiting studies have at least one site in Pennsylvania; 330 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in Pennsylvania.
943 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 1/Phase 2
RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus
Cabaletta Bio
- Location
- Philadelphia, PA + 17 other US sites
- Eligibility basics
- Ages 12–65
- RecruitingPhase 3
This Study Will Evaluate the Effectiveness of NTX-001, a Surgical Nerve Repair Product When Used in People With Upper Extremity Nerve Lacerations.
Neuraptive Therapeutics Inc.
- Location
- Philadelphia, PA + 22 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 2
Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986368, for the Treatment of Agitation in Participants With Alzheimer's Disease
Celgene
- Location
- Philadelphia, PA + 31 other US sites
- Eligibility basics
- Ages 55–90
- Recruiting
Alleviant ALLAY-HFrEF Study
Alleviant Medical, Inc.
- Location
- Harrisburg, PA + 38 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
ANCHOR Study: A Study to Assess the Safety and Efficacy of ABBV-CLS-628 in Adult Participants With Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Calico Life Sciences LLC
- Location
- Bethlehem, PA + 33 other US sites
- Eligibility basics
- Ages 18–55
- RecruitingPhase 2
A Study to Evaluate the Efficacy and Safety of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 Study)
Seaport Therapeutics
- Location
- Allentown, PA + 26 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 3
A Study to Evaluate the Pharmacokinetics, Safety and Efficacy of Afimkibart (RO7790121) in Children With Moderately to Severely Active Ulcerative Colitis
Hoffmann-La Roche
- Location
- Pittsburgh, PA + 7 other US sites
- Eligibility basics
- Ages 2–17
- RecruitingPhase 3
A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease
Hoffmann-La Roche
- Location
- Philadelphia, PA + 52 other US sites
- Eligibility basics
- Ages 50–85
- RecruitingPhase 2
Trial Against INtractable Type 2 Diabetes (CAPTAIN-T2D)
Sparrow Pharmaceuticals
- Location
- West Chester, PA + 60 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Pridopidine Phase 3 Study to Evaluate Efficacy and Safety in ALS
Prilenia
- Location
- Philadelphia, PA + 17 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 2
A Study of KT-621 Administered Orally to Adult Participants With Moderate to Severe Eosinophilic Asthma
Kymera Therapeutics, Inc.
- Location
- Philadelphia, PA + 30 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2
Phase 2 Study to Assess the Safety and Efficacy of ANG003
Anagram Therapeutics, Inc.
- Location
- Hershey, PA + 19 other US sites
- Eligibility basics
- Ages 12+
- RecruitingPhase 4
Evaluation of SPN-812 (Viloxazine Extended-release Capsule) in Preschool-age Children With ADHD
Supernus Pharmaceuticals, Inc.
- Location
- Hershey, PA + 38 other US sites
- Eligibility basics
- Ages 4–5
- Recruiting
Balance4Mobility: Effects of Walkasins Use in Individuals With Peripheral Neuropathy and Balance Problems
RxFunction Inc.
- Location
- Pittsburgh, PA + 3 other US sites
- Eligibility basics
- Ages 55+
- RecruitingPhase 3
Depemokimab as an Extended Treatment Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation (ENDURA-2)
GlaxoSmithKline
- Location
- DuBois, PA + 50 other US sites
- Eligibility basics
- Ages 40–80
- RecruitingPhase 2
A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy
Novo Nordisk A/S
- Location
- Camp Hill, PA + 16 other US sites
- Eligibility basics
- Ages 40–84
- Recruiting
Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure
Boston Scientific Corporation
- Location
- Philadelphia, PA + 39 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
A Phase 1b, Open-Label Study of DISC-3405 in Participants With Sickle Cell Disease (SCD)
Disc Medicine, Inc
- Location
- Pittsburgh, PA + 10 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2/Phase 3
A Study of the Efficacy and Safety of Danicamtiv in Participants With Symptomatic Genetic and Familial Dilated Cardiomyopathy
Kardigan, Inc.
- Location
- Philadelphia, PA + 26 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
EncompaSSc: Evaluation of MTX-474 in Participants With Diffuse Cutaneous Systemic Sclerosis (dcSSc)
Mediar Therapeutics
- Location
- Pittsburgh, PA + 13 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study of Brenipatide in Adult Participants With Major Depressive Disorder
Eli Lilly and Company
- Location
- Philadelphia, PA + 31 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-1-EXTENSION)
Amgen
- Location
- Newport, PA + 69 other US sites
- Eligibility basics
- Ages 18–99
- RecruitingPhase 3
CAR-T Long Term Follow Up (LTFU) Study
Novartis Pharmaceuticals
- Location
- Philadelphia, PA + 38 other US sites
- Eligibility basics
- Ages 0 mo–100
- RecruitingPhase 4
A Study Evaluating the Effectiveness and Safety of Risdiplam Administered as an Early Intervention in Pediatric Participants With Spinal Muscular Atrophy After Gene Therapy
Hoffmann-La Roche
- Location
- Philadelphia, PA + 9 other US sites
- Eligibility basics
- Ages 4 mo–2