Location · Pennsylvania
Clinical trials recruiting in Pennsylvania
943 recruiting studies have at least one site in Pennsylvania; 330 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in Pennsylvania.
943 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 3
Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People With Liver Disease and Scarring (Fibrosis) Due to an Abnormal Version of Alpha-1 Antitrypsin Protein
Takeda
- Location
- Hershey, PA + 32 other US sites
- Eligibility basics
- Ages 18–75
- Recruiting
The GORE VBX FORWARD Clinical Study: A Comparison of the GORE® VIABAHN® VBX Balloon Expandable Endoprosthesis to Bare Metal Stenting for Patients With Complex Iliac Occlusive Disease
W.L.Gore & Associates
- Location
- Philadelphia, PA + 22 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
Study of Sparsentan Treatment in Pediatrics With Proteinuric Glomerular Diseases
Travere Therapeutics, Inc.
- Location
- Philadelphia, PA + 16 other US sites
- Eligibility basics
- Ages 1–17
- RecruitingPhase 2
A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)
atai Therapeutics, Inc.
- Location
- Moosic, PA + 33 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 2
A Randomized Controlled Phase II Trial of STIMULAN VG vs Standard of Care (SoC) for the Treatment of Osteomyelitis Associated With Stage IV Pressure Ulcers.
Biocomposites Ltd
- Location
- Pittsburgh, PA + 8 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
A Randomized Study of SPK-10001 Gene Therapy in Participants With Huntington's Disease
Hoffmann-La Roche
- Location
- Philadelphia, PA + 4 other US sites
- Eligibility basics
- Ages 25–65
- RecruitingPhase 3
A Long-Term Study of JNT-517 in Participants With Phenylketonuria
Otsuka Pharmaceutical Development & Commercialization, Inc.
- Location
- Pittsburgh, PA + 7 other US sites
- Eligibility basics
- Ages 4+
- RecruitingPhase 2
A Study of the Effect of ZT-01 on Night-time Hypoglycemia in Type 1 Diabetes
Zucara Therapeutics Inc.
- Location
- Philadelphia, PA + 36 other US sites
- Eligibility basics
- Ages 18–75
- Recruiting
Evaluating the Safety and Efficacy of dNerva Lung Denervation System in Patients With COPD
Nuvaira, Inc.
- Location
- DuBois, PA + 5 other US sites
- Eligibility basics
- Ages 40–80
- RecruitingPhase 2
Efficacy and Safety of Obefazimod in Subjects With Moderately to Severely Active Crohn's Disease
Abivax S.A.
- Location
- Uniontown, PA + 23 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2
A Study of ORX750 in Participants With Narcolepsy and Idiopathic Hypersomnia
Centessa Pharmaceuticals (UK) Limited
- Location
- Willow Grove, PA + 26 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 2
A Study of TAK-411 in Adults With Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)
Takeda
- Location
- Philadelphia, PA + 11 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Cardiac RADIoablation Versus Repeat Catheter Ablation: a Pivotal Randomized Clinical Trial Evaluating Safety and Efficacy for Patients With High-risk Refractory Ventricular Tachycardia (RADIATE-VT)
Varian, a Siemens Healthineers Company
- Location
- Philadelphia, PA + 10 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2/Phase 3
Pharmacokinetics, Efficacy, and Safety of Encaleret in Pediatric Participants With Autosomal Dominant Hypocalcemia Type 1 (ADH1)
Calcilytix Therapeutics, Inc., a BridgeBio company
- Location
- Philadelphia, PA + 3 other US sites
- Eligibility basics
- Ages 0 mo–17
- RecruitingPhase 2
Study to Evaluate Sotatercept (MK-7962) in Children With Pulmonary Arterial Hypertension (PAH) (MK-7962-008)
Merck Sharp & Dohme LLC
- Location
- Philadelphia, PA + 8 other US sites
- Eligibility basics
- Ages 1–17
- Recruiting
PROMISE III: Percutaneous Deep Vein Arterialization for the Treatment of Late-Stage Chronic Limb-Threatening Ischemia
LimFlow, Inc.
- Location
- Philadelphia, PA + 7 other US sites
- Eligibility basics
- Ages 18–95
- RecruitingPhase 2
A Long-term Extension Study of ORX750 in Participants With Narcolepsy and Idiopathic Hypersomnia
Centessa Pharmaceuticals (UK) Limited
- Location
- Abington, PA + 18 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 3
Olpasiran Trials of Cardiovascular Events and Lipoprotein(a) Reduction - Coronary Computed Tomography Angiography Trial
Amgen
- Location
- Philadelphia, PA + 5 other US sites
- Eligibility basics
- Ages 35–80
- RecruitingPhase 1/Phase 2
Phase 1/2 Open-Label Dose-Escalation Study to Evaluate Safety of a Single Intravitreal Injection of RTx-021 in Patients With Stargardt Disease
Ray Therapeutics, Inc.
- Location
- Pittsburgh, PA + 2 other US sites
- Eligibility basics
- Ages 16+
- RecruitingPhase 1
AMX0114 in Adult Participants With Amyotrophic Lateral Sclerosis
Amylyx Pharmaceuticals Inc.
- Location
- Philadelphia, PA + 9 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR
Cardiac Dimensions, Inc.
- Location
- Lancaster, PA + 50 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
Study to Assess the Safety, Tolerability, and Preliminary Efficacy of ST266 in Infants With Necrotizing Enterocolitis (NEC)
Noveome Biotherapeutics, formerly Stemnion
- Location
- Hershey, PA + 7 other US sites
- Eligibility basics
- Ages 0 mo–2 mo
- RecruitingPhase 2
Impact of Obicetrapib and Obicetrapib Plus Repatha on Lp(a) Levels
NewAmsterdam Pharma
- Location
- Philadelphia, PA
- Eligibility basics
- Ages 18–75
- RecruitingPhase 4
A Study to Evaluate the Impact of Upadacitinib on Spondyloarthritis Outcomes in Patients With Active Psoriatic Arthritis
CARE ARTHRITIS LTD.
- Location
- Philadelphia, PA + 2 other US sites
- Eligibility basics
- Ages 18+