Study type
Heart and blood pressure studies recruiting now
Cardiovascular studies cover high blood pressure, high cholesterol, heart failure, atrial fibrillation and coronary artery disease, among others.
494 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
More recruiting studies (pay not posted)
- Recruiting
Conquer-AF Protocol for Redo Ablation Procedures in Recurrent Paroxysmal and Persistent Atrial Fibrillation Using the Sphere-9 Catheter and Affera Ablation System (Conquer-AF)
Medtronic Cardiac Ablation Solutions
- Location
- Birmingham, AL + 20 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
BIOTRONIK Investigation of the LivIQ Leadless Pacemaker System
Biotronik, Inc.
- Location
- Burlingame, CA + 23 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Elite AF IDE Trial (Elite AF)
Boston Scientific Corporation
- Location
- Jonesboro, AR + 1 other US site
- Eligibility basics
- Ages 18+
- Recruiting
NORM-HF Pivotal Study
Foundry Innovation & Research 1, Limited (FIRE1)
- Location
- Chula Vista, CA + 22 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
Resmetirom in Patients With MASH and HFpEF
Madrigal Pharmaceuticals, Inc.
- Location
- Peoria, AZ + 4 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
LAM-001 for the Treatment of Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
IRulya Therapeutics Inc.
- Location
- Tucson, AZ + 1 other US site
- Eligibility basics
- Ages 18–85
- Recruiting
Renal Pelvic Denervation Pilot Trial
Verve Medical, Inc
- Location
- Birmingham, AL + 7 other US sites
- Eligibility basics
- Ages 21–80
- RecruitingPhase 3
Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease
Alnylam Pharmaceuticals
- Location
- Birmingham, AL + 213 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
Study of Efficacy and Safety of Tonlamarsen in Participants With a Recent Hospitalization and a Concurrent Episode of Acute Severe Hypertension
Kardigan, Inc.
- Location
- Arvada, CO + 11 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
Dose-finding Study of YMI024 to Assess Efficacy, Safety, and Tolerability in Adults With Stable Coronary Artery Disease and Elevated hsCRP
Novartis Pharmaceuticals
- Location
- Fairhope, AL + 8 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 3
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
Boehringer Ingelheim
- Location
- Mobile, AL + 91 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart
Boehringer Ingelheim
- Location
- Covina, CA + 78 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
Boehringer Ingelheim
- Location
- Anniston, AL + 199 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Phase 3 Study to Evaluate the Safety and Efficacy L606 in Participants With PH-ILD
Liquidia Technologies, Inc.
- Location
- Phoenix, AZ + 12 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 3
Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation for Whom Oral Anticoagulation is Unsuitable
Regeneron Pharmaceuticals
- Location
- Dothan, AL + 42 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Open-label Extension Study of Seralutinib in Adult Subjects With PAH (PROSERA-EXT)
Gossamer Bio USA, Inc.
- Location
- Fresno, CA + 28 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function
AstraZeneca
- Location
- Alexander City, AL + 93 other US sites
- Eligibility basics
- Ages 18–130
- RecruitingPhase 3
Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction
Cytokinetics
- Location
- Alexander City, AL + 80 other US sites
- Eligibility basics
- Ages 18–85
- Recruiting
Fluid Management of Acute Decompensated Heart Failure Subjects Treated With Reprieve System (FASTR-II) (IDE-G210258)
Reprieve Cardiovascular, Inc
- Location
- Irvine, CA + 33 other US sites
- Eligibility basics
- Ages 22+
- Recruiting
INitiation and Titration of Guideline Directed Medical TheRApy in HearT Failure Cardiogenic Shock With ImpElla 5.5 for Cardiac Recovery
Abiomed Inc.
- Location
- Tampa, FL + 1 other US site
- Eligibility basics
- Ages 18–80
- Recruiting
EVERO Drug-coated Balloon (DCB) Randomized Trial
Cook Research Incorporated
- Location
- Long Beach, CA + 11 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Efficacy and Safety Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
Insmed Incorporated
- Location
- Los Angeles, CA + 12 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Evaluate the Efficacy and Safety of Once Daily Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Arterial Hypertension (PAH)
Insmed Incorporated
- Location
- Los Angeles, CA + 10 other US sites
- Eligibility basics
- Ages 18–75
- Recruiting
Safety and Effectiveness of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere VT)
Medtronic Cardiac Ablation Solutions
- Location
- Indianapolis, IN + 4 other US sites
- Eligibility basics
- Ages 18–85
Who these studies look for
Many require a diagnosis or specific lab values such as LDL cholesterol or blood pressure readings, and exclude recent heart events.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Do heart studies include healthy people?
Some do, especially early-phase studies and those measuring heart effects of new medicines. Check whether a listing says it accepts healthy volunteers.