Study type
Heart and blood pressure studies recruiting now
Cardiovascular studies cover high blood pressure, high cholesterol, heart failure, atrial fibrillation and coronary artery disease, among others.
494 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
More recruiting studies (pay not posted)
- Recruiting
ELEVATE-HFpEF Clinical Study
Medtronic Cardiac Rhythm and Heart Failure
- Location
- Phoenix, AZ + 25 other US sites
- Eligibility basics
- Ages 40+
- RecruitingPhase 2
A Study of Modified Release RTN-001 In Patients With Uncontrolled Hypertension
Retension Pharmaceuticals. Inc.
- Location
- Alexander City, AL + 31 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
BHB-1893 Versus Metoprolol for Symptomatic Obstructive Hypertrophic Cardiomyopathy
Braveheart Bio, Inc.
- Location
- Manhasset, NY + 2 other US sites
- Eligibility basics
- Ages 18–85
- RecruitingPhase 4
A Study of Inhaled Treprostinil (LIQ861) in Adults With Pulmonary Arterial Hypertension Transitioning From Oral Selexipag
Liquidia Technologies, Inc.
- Location
- Columbus, GA
- Eligibility basics
- Ages 18–80
- RecruitingPhase 3
A Study of the Long-term Safety and Efficacy of Danicamtiv in Adults With Symptomatic Genetic and Familial Dilated Cardiomyopathy
Kardigan, Inc.
- Location
- Birmingham, AL + 2 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
A Phase 1 AAV Gene Therapy Trial Evaluating Safety and Preliminary Efficacy of RP-A701 in Subjects With BAG3 Dilated Cardiomyopathy
Rocket Pharmaceuticals Inc.
- Location
- San Diego, CA + 2 other US sites
- Eligibility basics
- Ages 18–65
- Recruiting
MBA Early Feasibility Study
W.L.Gore & Associates
- Location
- Los Angeles, CA + 2 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Efficacy of the COronary SInus Reducer in Patients With Refractory Angina II
Shockwave Medical, Inc.
- Location
- Phoenix, AZ + 66 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
A Study Assessing Long-Term Safety and Effectiveness in Treatment Management of Atrial Fibrillation With VARIPULSE Catheter System
Biosense Webster, Inc.
- Location
- Phoenix, AZ + 22 other US sites
- Eligibility basics
- Ages 22+
- RecruitingPhase 1/Phase 2
HS235 Study in Overweight and Obese Participants With Combined Pre and Post-Capillary Pulmonary Hypertension Due to Heart Failure With Preserved Ejection Fraction
35Pharma Inc
- Location
- Kansas City, MO + 1 other US site
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study to Evaluate the Efficacy, Safety, Pharmacodynamics (PD), and Pharmacokinetics (PK) of Selnoflast in Reducing Vascular Inflammation in Participants With Atherosclerosis at Risk for Major Adverse Cardiac Events
Genentech, Inc.
- Location
- Beverly Hills, CA + 23 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
kTMP-Enhanced Motor Rehabilitation for Chronic Stroke Recovery (KULMINATE) Pilot
Magnetic Tides
- Location
- San Francisco, CA
- Eligibility basics
- Ages 18–80
- Recruiting
BiVACOR® Total Artificial Heart Early Feasibility Study
BiVACOR Inc.
- Location
- Phoenix, AZ + 3 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 2
A Study to Investigate the Efficacy, Safety, Tolerability and Pharmacokinetics of PKN605 in Participants With Atrial Fibrillation
Novartis Pharmaceuticals
- Location
- Tupelo, MS + 5 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
REGN22530 for Adults With Primary Open Angle Glaucoma or Ocular Hypertension
Regeneron Pharmaceuticals
- Location
- Deerfield Beach, FL
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF
AstraZeneca
- Location
- Fairhope, AL + 8 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure
AstraZeneca
- Location
- Fairhope, AL + 104 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
Study of REGN13335 in Adult Participants With Pulmonary Arterial Hypertension (PAH)
Regeneron Pharmaceuticals
- Location
- Aurora, CO + 3 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
A Study of VARIPULSE Catheter in Participants With Persistent Atrial Fibrillation Undergoing Pulmonary Vein and Superior Vena Cava Isolation
Biosense Webster, Inc.
- Location
- Birmingham, AL + 10 other US sites
- Eligibility basics
- Ages 18–80
- Recruiting
ALLIANCE: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve
Edwards Lifesciences
- Location
- Los Angeles, CA + 30 other US sites
- Eligibility basics
- Any age listed
- Recruiting
THRIVE- THerapeutic IntravasculaR Ultrasound (TIVUS™) REnal Denervation System Versus Sham for the Adjunctive Treatment of Hypertension
SoniVie Inc.
- Location
- Birmingham, AL + 33 other US sites
- Eligibility basics
- Ages 22–75
- RecruitingPhase 3
Assessing the Impact of Muvalaplin on Major Cardiovascular Events in Adults With Elevated Lipoprotein(a)
Eli Lilly and Company
- Location
- Gilbert, AZ + 120 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
To Evaluate the Safety and Efficacy of MANP in Subjects With Difficult to Control/ Resistant Hypertension
E-Star BioTech, LLC
- Location
- Little Rock, AR + 21 other US sites
- Eligibility basics
- Ages 18–80
- Recruiting
Evaluation of Liver Stiffness Performance, by FibroScan®, to Detect Elevated Central Venous Pressure (CVP)
Echosens
- Location
- Minneota, MN + 2 other US sites
- Eligibility basics
- Ages 18+
Who these studies look for
Many require a diagnosis or specific lab values such as LDL cholesterol or blood pressure readings, and exclude recent heart events.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Do heart studies include healthy people?
Some do, especially early-phase studies and those measuring heart effects of new medicines. Check whether a listing says it accepts healthy volunteers.