Phase 1 · Michigan
Phase 1 clinical trials in Michigan
47 studies have at least one recruiting site in Michigan. Phase 1 (and early Phase 1) trials are usually the first time a medicine is studied in people. They are typically small, closely monitored, and many are run in dedicated research units, sometimes with overnight stays.
47 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteersPhase 1/Phase 2
A Study of BLB-201 RSV Vaccine in Infants and Children
Blue Lake Biotechnology Inc.
- Location
- Allen Park, MI + 13 other US sites
- Eligibility basics
- Ages 6 mo–5
- RecruitingHealthy volunteersPhase 1
Study to Evaluate the Safety, Pharmacokinetic, and Pharmacodynamic Effects of MY006 in Healthy Volunteers and Patients With Peanut Allergy
Mabylon AG
- Location
- Ann Arbor, MI + 7 other US sites
- Eligibility basics
- Ages 12–55
- RecruitingHealthy volunteersPhase 1
A Clinical Trial of LY3962681 in Healthy Volunteers and in Patients With Parkinson's Disease
Prevail Therapeutics
- Location
- Farmington Hills, MI + 1 other US site
- Eligibility basics
- Ages 30–80
- RecruitingHealthy volunteersPhase 1
A Study of LY4006896 in Healthy Participants and Participants With Parkinson's Disease
Eli Lilly and Company
- Location
- Farmington Hills, MI + 7 other US sites
- Eligibility basics
- Ages 30–85
- RecruitingHealthy volunteersPhase 1/Phase 2
Phase 1/2 Study of Respiratory Syncytial Virus and Human Metapneumovirus (RSV+HMPV) Vaccine Candidate in Adults 60 Years of Age and Older
Sanofi
- Location
- Farmington Hills, MI + 49 other US sites
- Eligibility basics
- Ages 60+
- RecruitingHealthy volunteersPhase 1
FIH Study to Evaluate the Tolerability of PF-07832837 in Healthy Adults and Patients
Pfizer
- Location
- Troy, MI + 4 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingHealthy volunteersPhase 1
A Study of Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SR604 in Two Participants Groups (Part A: Healthy Participants, and Part B: Participants With Hemophilia A or Hemophilia B or Factor VII…
Equilibra Bioscience LLC
- Location
- Ann Arbor, MI + 6 other US sites
- Eligibility basics
- Ages 18–60
- RecruitingHealthy volunteersPhase 1
Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics And Pharmacodynamics of SIF001 in Healthy Subjects and in Epilepsy Patients
Suninflam Inc
- Location
- Farmington Hills, MI + 9 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingHealthy volunteersEarly Phase 1
Feasibility and Safety of MB-102 in Ocular Angiography as Compared to Fluorescein Sodium
MediBeacon
- Location
- Ann Arbor, MI
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 1
The Impact of Light Exposure on Cognitive Function in Classrooms
Michigan State University
- Location
- East Lansing, MI
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 1/Phase 2
Sleep Disordered Breathing With Opioid Use
VA Office of Research and Development
- Location
- Detroit, MI
- Eligibility basics
- Ages 18–89
- RecruitingHealthy volunteersEarly Phase 1
Positron Emission Tomography (PET) Imaging of Cholesterol Trafficking: Clinical Evaluation of [18F]FNP-59 in Normal Human Subjects (Group 1)
Benjamin Viglianti
- Location
- Ann Arbor, MI
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersEarly Phase 1
Positron Emission Tomography (PET) Imaging of Cholesterol Trafficking: Clinical Evaluation of [18F]FNP-59 in Normal Human Subjects (Groups 2, 3 & 4)
Benjamin Viglianti
- Location
- Ann Arbor, MI
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 1
Ondansetron Use for Preventing Pruritus in Patients Undergoing Cesarean Section
Wayne State University
- Location
- Detroit, MI
- Eligibility basics
- Ages 18–50 · Women only
- RecruitingPhase 1/Phase 2
A Clinical Study to Evaluate the Safety and Efficacy of ETX101 in Infants and Children With SCN1A-Positive Dravet Syndrome
Encoded Therapeutics
- Location
- Ann Arbor, MI + 9 other US sites
- Eligibility basics
- Ages 6 mo–17
- RecruitingPhase 1/Phase 2
A Study to Investigate the Safety and Effectiveness of a Coagulation Factor IX Gene Insertion Therapy (REGV131-LNP1265) in Pediatric, Adolescent and Adult Participants With Hemophilia B
Regeneron Pharmaceuticals
- Location
- Ann Arbor, MI + 16 other US sites
- Eligibility basics
- Ages 2+ · Men only
- RecruitingPhase 1
A Clinical Study of Letermovir (MK-8228) in Children and Adolescents Who Receive a Kidney Transplant (KT) (MK-8228-077)
Merck Sharp & Dohme LLC
- Location
- Ann Arbor, MI + 20 other US sites
- Eligibility basics
- Up to age 17
- RecruitingPhase 1
A Phase 1 Study of LY5830966 in Participants With Primary Myelofibrosis (PMF), Post-Polycythemia Vera Myelofibrosis (PPV-MF), or Post-Essential Thrombocythemia Myelofibrosis (PET-MF) Who Have Been Failed by a Type I…
Ajax Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and Company
- Location
- Ann Arbor, MI + 12 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
Study to Evaluate ACDN-01 in ABCA4-related Stargardt Retinopathy (STELLAR)
Ascidian Therapeutics, Inc
- Location
- Ann Arbor, MI + 8 other US sites
- Eligibility basics
- Ages 12+
- RecruitingPhase 1/Phase 2
A Study of Oral Nuvisertib (TP-3654) in Patients With Myelofibrosis
Sumitomo Pharma America, Inc.
- Location
- Ann Arbor, MI + 29 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
A Study to Evaluate the Efficacy and Safety of Cannabidiol Oral Solution (CBD-OS [GWP42003-P, JZP926]) for the Treatment of Focal-Onset Seizures
Jazz Pharmaceuticals
- Location
- Detroit, MI + 20 other US sites
- Eligibility basics
- Ages 12–75
- RecruitingPhase 1
A Study of the Feasibility, Safety and Tolerability of Aticaprant as Adjunctive Treatment in Participants With Schizophrenia
Janssen Research & Development, LLC
- Location
- Kalamazoo, MI + 7 other US sites
- Eligibility basics
- Ages 18–55
- RecruitingPhase 1/Phase 2
CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D)
COUR Pharmaceutical Development Company, Inc.
- Location
- Ann Arbor, MI + 44 other US sites
- Eligibility basics
- Ages 12–35
- RecruitingPhase 1
A Study to Assess the Safety and Clinical Activity of Azer-cel in Participants With B-cell Mediated Autoimmune Disorders
TG Therapeutics, Inc.
- Location
- Ann Arbor, MI + 7 other US sites
- Eligibility basics
- Ages 18+
Who these studies look for
Phase 1 studies often have narrow eligibility: specific age and weight ranges, no recent participation in another study, no nicotine, and limits on medications. Some Phase 1 studies recruit patients rather than healthy volunteers, so check each listing.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Are Phase 1 trials riskier?
Every study carries risk. Phase 1 studies involve less human data about the product, which is why they are closely monitored. The informed consent document explains the known risks; read it carefully and ask questions before signing.
Why do some Phase 1 studies include overnight stays?
Staying in the unit lets staff dose on a precise schedule and collect samples around the clock. Where a record mentions an inpatient stay we flag it on the listing.