Phase 1 · Texas
Phase 1 clinical trials in Texas
202 studies have at least one recruiting site in Texas. Phase 1 (and early Phase 1) trials are usually the first time a medicine is studied in people. They are typically small, closely monitored, and many are run in dedicated research units, sometimes with overnight stays.
202 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteersPhase 1
A Study to Evaluate the Impact of Renal Impairment on the Pharmacokinetics (PK) of Ribupatide
Kailera
- Location
- San Antonio, TX + 1 other US site
- Eligibility basics
- Ages 18–85
- RecruitingHealthy volunteersPhase 1/Phase 2
Study of XmAb942 in Healthy Participants and Participants With Ulcerative Colitis
Xencor, Inc.
- Location
- Cedar Park, TX + 27 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingHealthy volunteersPhase 1/Phase 2
First-in-human Study of the Safety, Tolerability, Pharmacokinetics, and Food Effect of ACCG-2671
Aconcagua Bio, Inc. a wholly owned subsidiary of Structure Therapeutics
- Location
- Webster, TX + 2 other US sites
- Eligibility basics
- Ages 25–75
- RecruitingHealthy volunteersPhase 1
A Study to Evaluate the Pharmacokinetics (PK) and Safety of a Single Dose of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Normal Hepatic Function and Participants With Hepatic Impairment
Insmed Incorporated
- Location
- San Antonio, TX + 3 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingHealthy volunteersPhase 1
A Study Evaluating MDX2301 in Healthy Adults and Adults at Higher Risk for Severe COVID-19.
ModeX Therapeutics, An OPKO Health Company
- Location
- Austin, TX + 1 other US site
- Eligibility basics
- Ages 18–64
- RecruitingHealthy volunteersPhase 1
A First-in-Human Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of HMB-003 in Healthy Volunteers
Hemab ApS
- Location
- San Antonio, TX
- Eligibility basics
- Ages 18–50
- RecruitingHealthy volunteersPhase 1
Comparative PK Assessment Study of Casdatifan in Moderate Hepatically Impaired Participants Versus Matched Participants With Normal Hepatic Function
Arcus Biosciences, Inc.
- Location
- San Antonio, TX
- Eligibility basics
- Ages 18–84
- RecruitingHealthy volunteersPhase 1
A Study to Assess Zilucoplan Concentration in Breast Milk of Healthy Lactating Women
UCB Biopharma SRL
- Location
- San Antonio, TX + 1 other US site
- Eligibility basics
- Ages 18+ · Women only
- RecruitingHealthy volunteersPhase 1
A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4248 in Healthy Participants and Participants With Chronic Kidney Disease and Type 2 Diabetes and to Assess Home Measurements of…
AstraZeneca
- Location
- San Antonio, TX + 3 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingHealthy volunteersPhase 1
First Time in Human Study of Long Acting VH4524184 Formulations
ViiV Healthcare
- Location
- San Antonio, TX + 2 other US sites
- Eligibility basics
- Ages 18–55
- RecruitingHealthy volunteersPhase 1
Phase I Study to Assess the Safety and Efficacy of OCU200 for Center-Involved Diabetic Macular Edema (DME)
Ocugen
- Location
- Bellaire, TX + 4 other US sites
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 1
A Study of LY4515100 in Healthy Participants
Eli Lilly and Company
- Location
- Dallas, TX
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 1
A Comparative Study to Investigate the Difference in Blood Levels of Two Different Formulations of GSK5784283
GlaxoSmithKline
- Location
- Austin, TX
- Eligibility basics
- Ages 18–60
- RecruitingHealthy volunteersPhase 1/Phase 2
A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)
Novartis Pharmaceuticals
- Location
- Austin, TX + 18 other US sites
- Eligibility basics
- Ages 18–100
- RecruitingHealthy volunteersPhase 1/Phase 2
Safety and Efficacy of SUM-191 for Patients With Bacterial Conjunctivitis
Senju USA, Inc.
- Location
- Austin, TX
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 1
Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics And Pharmacodynamics of SIF001 in Healthy Subjects and in Epilepsy Patients
Suninflam Inc
- Location
- Cypress, TX + 9 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingHealthy volunteersPhase 1
A Trial to Compare the Pharmacokinetics of Two Presentations of Navenibart in Healthy Participants
Astria Therapeutics, Inc.
- Location
- Dallas, TX + 2 other US sites
- Eligibility basics
- Ages 18–55
- RecruitingHealthy volunteersPhase 1
Pharmacokinetic Study of Vorasidenib in Severe Hepatically Impaired and Matched-Control Participants
Institut de Recherches Internationales Servier (I.R.I.S.)
- Location
- San Antonio, TX + 2 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingHealthy volunteersPhase 1
A Study of Eloralintide (LY3841136) in Participants With Different Levels of Liver Damage and in Participants With Healthy Livers.
Eli Lilly and Company
- Location
- San Antonio, TX + 1 other US site
- Eligibility basics
- Ages 18–85
- RecruitingHealthy volunteersPhase 1/Phase 2
A Phase 1/2a Study of DB-2304 in Healthy Adults and SLE/CLE Participants
DualityBio Inc.
- Location
- Irving, TX + 4 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingHealthy volunteersPhase 1
A Study of Mirikizumab Solution (LY3074828) in Healthy Participants
Eli Lilly and Company
- Location
- Dallas, TX + 4 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 1
A Study to Test How BI 3000202 is Taken up in the Blood of People With and Without Liver Problems
Boehringer Ingelheim
- Location
- San Antonio, TX
- Eligibility basics
- Ages 18–80
- RecruitingHealthy volunteersPhase 1/Phase 2
A Study on the Safety and Immune Response of a Urinary Tract Infection (UTI) Vaccine in Adults 18-64 Years of Age and Clinical Efficacy in Females 18-64 Years of Age
GlaxoSmithKline
- Location
- Weatherford, TX + 5 other US sites
- Eligibility basics
- Ages 18–64
- RecruitingHealthy volunteersPhase 1
A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Doses of EDP-978 in Healthy Adults
Enanta Pharmaceuticals, Inc
- Location
- San Antonio, TX
- Eligibility basics
- Ages 18–65
Who these studies look for
Phase 1 studies often have narrow eligibility: specific age and weight ranges, no recent participation in another study, no nicotine, and limits on medications. Some Phase 1 studies recruit patients rather than healthy volunteers, so check each listing.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Are Phase 1 trials riskier?
Every study carries risk. Phase 1 studies involve less human data about the product, which is why they are closely monitored. The informed consent document explains the known risks; read it carefully and ask questions before signing.
Why do some Phase 1 studies include overnight stays?
Staying in the unit lets staff dose on a precise schedule and collect samples around the clock. Where a record mentions an inpatient stay we flag it on the listing.