Phase 1 · Texas
Phase 1 clinical trials in Texas
202 studies have at least one recruiting site in Texas. Phase 1 (and early Phase 1) trials are usually the first time a medicine is studied in people. They are typically small, closely monitored, and many are run in dedicated research units, sometimes with overnight stays.
202 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 1
A Study in Adult Males With X-linked Congenital Nephrogenic Diabetes Insipidus to Test the Effects of NDI-5001 Given for Multiple Days and to Test How NDI-5001 is Tolerated and Taken up in the Body
Otsuka Pharmaceutical Development & Commercialization, Inc.
- Location
- San Antonio, TX + 1 other US site
- Eligibility basics
- Ages 18–55 · Men only
- RecruitingPhase 1
A Study to Assess Adverse Events, How the Drug Moves Through the Body and Effectiveness of Intravenous Infusions and Subcutaneous Injections of ABBV-519 in Adult Participants With Systemic Lupus Erythematosus (SLE) or…
AbbVie
- Location
- Houston, TX + 11 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1/Phase 2
RESET-MG: A Study to Evaluate the Safety and Efficacy of CABA-201 in Participants With Generalized Myasthenia Gravis
Cabaletta Bio
- Location
- Houston, TX + 16 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 1
Evaluation of the Tolerability of Cagrilintide in Participants Not Tolerating GLP-1-RA Therapies Due to Gastrointestinal Adverse Events
Novo Nordisk A/S
- Location
- Amarillo, TX + 9 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
A Study to Learn About the Safety of BIIB147 and Its Effects in Adults With Amyotrophic Lateral Sclerosis (ALS)
Biogen
- Location
- Austin, TX + 1 other US site
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
DFT383 in Pediatric Participants With Nephropathic Cystinosis
Novartis Pharmaceuticals
- Location
- Houston, TX + 5 other US sites
- Eligibility basics
- Ages 2–5
- RecruitingPhase 1/Phase 2
An Optimised GA Interventional Trial (Opti-GAIN) to Test if Treatment With CTx001 is Safe and Works for People With Geographic Atrophy (GA)
Complement Therapeutics
- Location
- Dallas, TX + 3 other US sites
- Eligibility basics
- Ages 55+
- RecruitingPhase 1/Phase 2
A Phase 1/2, Open-label, Safety and Dosing Study of Autologous CART Cells (Desmoglein 3 Chimeric Autoantibody Receptor T Cells [DSG3-CAART] or CD19-specific Chimeric Antigen Receptor T Cells [CABA-201]) in Subjects With…
Cabaletta Bio
- Location
- Dallas, TX + 9 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
A Study to Investigate the Safety of OpCT-001 in Adults Who Have Primary Photoreceptor Disease (CLARICO)
BlueRock Therapeutics
- Location
- Dallas, TX + 4 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
A Study in People With Diabetic Macular Edema to Test How Well Different Doses of BI 3812465 Are Tolerated
Boehringer Ingelheim
- Location
- Austin, TX + 24 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
Study to Evaluate the Pharmacokinetics (PK), Safety and Tolerability up to 6 Years of Intravenous (i.v.) Secukinumab in Pediatric Participants With Juvenile Psoriatic Arthritis (JPsA).
Novartis Pharmaceuticals
- Location
- El Paso, TX + 10 other US sites
- Eligibility basics
- Ages 2–17
- RecruitingPhase 1/Phase 2
A Study to Evaluate Topical ATR04-484 for EGFRi-Associated Dermal Toxicity
Azitra Inc.
- Location
- Houston, TX + 5 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
Safety, PK and PD of FLQ-101 in Premature Neonates
FELIQS INC.
- Location
- Austin, TX
- Eligibility basics
- Ages 0 mo–0 mo
- RecruitingPhase 1
A Clinical Study of Letermovir (MK-8228) in Children and Adolescents Who Receive a Kidney Transplant (KT) (MK-8228-077)
Merck Sharp & Dohme LLC
- Location
- Houston, TX + 20 other US sites
- Eligibility basics
- Up to age 17
- RecruitingPhase 1/Phase 2
A Study to Evaluate Safety, Tolerability, and Efficacy of AB-1009 Gene Therapy (GAA Gene) in Adult Participants With Late-Onset Pompe Disease (PROGRESS-GT LOPD)
AskBio Inc
- Location
- Dallas, TX + 4 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 1
A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of RO7663498 Following Intravitreal Administration in Participants With Diabetic Retinopathy
Hoffmann-La Roche
- Location
- San Antonio, TX + 3 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
Phase 1b/2 Study of IV Sarilumab in Adult With RA
Sanofi
- Location
- El Paso, TX + 11 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
A Phase 1 Study of LY5830966 in Participants With Primary Myelofibrosis (PMF), Post-Polycythemia Vera Myelofibrosis (PPV-MF), or Post-Essential Thrombocythemia Myelofibrosis (PET-MF) Who Have Been Failed by a Type I…
Ajax Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and Company
- Location
- Houston, TX + 12 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
A Study of Pirtobrutinib in Participants With Immune Thrombocytopenia
Eli Lilly and Company
- Location
- Austin, TX + 7 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
A Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of RO7823653 in Participants With Diabetic Macular Edema (DME)
Genentech, Inc.
- Location
- Abilene, TX + 11 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
ATTUNE: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Intrathecally-Administered ION440 in Participants With Methyl CpG Binding Protein 2 (MECP2) Duplication Syndrome (MDS)
Ionis Pharmaceuticals, Inc.
- Location
- Houston, TX + 7 other US sites
- Eligibility basics
- Ages 2–65 · Men only
- RecruitingPhase 1/Phase 2
Study to Evaluate ACDN-01 in ABCA4-related Stargardt Retinopathy (STELLAR)
Ascidian Therapeutics, Inc
- Location
- Dallas, TX + 8 other US sites
- Eligibility basics
- Ages 12+
- RecruitingPhase 1/Phase 2
RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus
Cabaletta Bio
- Location
- Houston, TX + 17 other US sites
- Eligibility basics
- Ages 12–65
- RecruitingPhase 1
A Study to Assess Sulbactam-durlobactam in Pediatric Patients With Acinetobacter Baumannii-calcoaceticus Complex Infection
Innoviva Specialty Therapeutics
- Location
- Galveston, TX + 3 other US sites
- Eligibility basics
- Ages 0 mo–18
Who these studies look for
Phase 1 studies often have narrow eligibility: specific age and weight ranges, no recent participation in another study, no nicotine, and limits on medications. Some Phase 1 studies recruit patients rather than healthy volunteers, so check each listing.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Are Phase 1 trials riskier?
Every study carries risk. Phase 1 studies involve less human data about the product, which is why they are closely monitored. The informed consent document explains the known risks; read it carefully and ask questions before signing.
Why do some Phase 1 studies include overnight stays?
Staying in the unit lets staff dose on a precise schedule and collect samples around the clock. Where a record mentions an inpatient stay we flag it on the listing.