Phase 1 · Virginia
Phase 1 clinical trials in Virginia
41 studies have at least one recruiting site in Virginia. Phase 1 (and early Phase 1) trials are usually the first time a medicine is studied in people. They are typically small, closely monitored, and many are run in dedicated research units, sometimes with overnight stays.
41 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteersPhase 1/Phase 2
Phase 1/2 Study of Respiratory Syncytial Virus and Human Metapneumovirus (RSV+HMPV) Vaccine Candidate in Adults 60 Years of Age and Older
Sanofi
- Location
- Charlottesville, VA + 49 other US sites
- Eligibility basics
- Ages 60+
- RecruitingHealthy volunteersPhase 1
A Clinical Study of Novel Pneumococcal Vaccine V118C in Children (V118C-002)
Merck Sharp & Dohme LLC
- Location
- Charlottesville, VA + 14 other US sites
- Eligibility basics
- Ages 2 mo–1
- RecruitingHealthy volunteersPhase 1/Phase 2
Study of XmAb942 in Healthy Participants and Participants With Ulcerative Colitis
Xencor, Inc.
- Location
- Richmond, VA + 27 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingHealthy volunteersPhase 1
Clinical Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of HT31-1 for Treating ARDS
HTIC, Inc
- Location
- Richmond, VA
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 1/Phase 2
Study to Assess Safety and Immunogenicity of an Egg-based H5N8 Influenza Vaccine at Multiple Dose Levels Adjuvanted With Matrix-M in Healthy Participants 18 Years of Age and Above.
Sanofi
- Location
- Charlottesville, VA + 15 other US sites
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 1
Phase 1 Study of Intravaginal KB15A
ZabBio Inc.
- Location
- Norfolk, VA
- Eligibility basics
- Ages 18–45 · Women only
- RecruitingHealthy volunteersPhase 1/Phase 2
A Study to Evaluate BMS-986470 in Healthy Volunteers and Participants With Sickle Cell Disease
Bristol-Myers Squibb
- Location
- Fairfax, VA + 8 other US sites
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 1/Phase 2
A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)
Novartis Pharmaceuticals
- Location
- Richmond, VA + 18 other US sites
- Eligibility basics
- Ages 18–100
- RecruitingHealthy volunteersPhase 1
Sustained Acoustic Medicine (SAM) for Symptomatic Treatment of Pain Related to Bone Fracture
ZetrOZ, Inc.
- Location
- Lansdowne, VA + 1 other US site
- Eligibility basics
- Ages 18–80
- RecruitingHealthy volunteersPhase 1
Impact of Early ADL Education on Outcomes Post DRF ORIF
George Washington University
- Location
- Washington, VA
- Eligibility basics
- Ages 18–110
- RecruitingHealthy volunteersEarly Phase 1
Sleep, Dreaming, and Virtual Reality for Mental Health
Northwestern University
- Location
- Charlottesville, VA + 1 other US site
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 1
Safety and Tolerability Study of VVZ-2471 in Healthy Volunteers
Virginia Commonwealth University
- Location
- Richmond, VA
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersEarly Phase 1
Psilocybin for Prolonged Grief Disorder
University of Virginia
- Location
- Charlottesville, VA
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersEarly Phase 1
Effect of Melatonin on Sleep Patterns of Resident Trainees During Night Float Shift
University of Virginia
- Location
- Charlottesville, VA
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersEarly Phase 1
Acute Progesterone Suppression of Wake vs. Sleep Luteinizing Hormone Pulse Frequency in Pubertal Girls With and Without Hyperandrogenism
University of Virginia
- Location
- Charlottesville, VA
- Eligibility basics
- Ages 10–17 · Women only
- RecruitingHealthy volunteersEarly Phase 1
Hyperandrogenemia and Altered Day-night LH Pulse Patterns
University of Virginia
- Location
- Charlottesville, VA
- Eligibility basics
- Ages 10–17 · Women only
- RecruitingHealthy volunteersEarly Phase 1
Study to Assess Potential Impairments in Estradiol Augmentation of Gonadotropin Secretion in Polycystic Ovary Syndrome
University of Virginia
- Location
- Charlottesville, VA
- Eligibility basics
- Ages 18–30 · Women only
- RecruitingHealthy volunteersEarly Phase 1
Does Spironolactone Normalize Sleep-wake Luteinizing Hormone Pulse Frequency in Pubertal Girls With Hyperandrogenism?
University of Virginia
- Location
- Charlottesville, VA
- Eligibility basics
- Ages 10–17 · Women only
- RecruitingHealthy volunteersPhase 1/Phase 2
Vaginal Microbiome Seeding and Health Outcomes in Cesarean-delivered Neonates.
National Institute of Allergy and Infectious Diseases (NIAID)
- Location
- Falls Church, VA
- Eligibility basics
- Ages 0 mo–50
- RecruitingHealthy volunteersPhase 1/Phase 2
Hyperpolarized Xenon-129 MR Imaging of the Lung
University of Virginia
- Location
- Charlottesville, VA
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
A Study in People With Diabetic Macular Edema to Test How Well Different Doses of BI 3812465 Are Tolerated
Boehringer Ingelheim
- Location
- Falls Church, VA + 24 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
A Study to Evaluate Topical ATR04-484 for EGFRi-Associated Dermal Toxicity
Azitra Inc.
- Location
- Fairfax, VA + 5 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
A Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of RO7823653 in Participants With Diabetic Macular Edema (DME)
Genentech, Inc.
- Location
- Lynchburg, VA + 11 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
A Study of Oral Nuvisertib (TP-3654) in Patients With Myelofibrosis
Sumitomo Pharma America, Inc.
- Location
- Charlottesville, VA + 29 other US sites
- Eligibility basics
- Ages 18+
Who these studies look for
Phase 1 studies often have narrow eligibility: specific age and weight ranges, no recent participation in another study, no nicotine, and limits on medications. Some Phase 1 studies recruit patients rather than healthy volunteers, so check each listing.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Are Phase 1 trials riskier?
Every study carries risk. Phase 1 studies involve less human data about the product, which is why they are closely monitored. The informed consent document explains the known risks; read it carefully and ask questions before signing.
Why do some Phase 1 studies include overnight stays?
Staying in the unit lets staff dose on a precise schedule and collect samples around the clock. Where a record mentions an inpatient stay we flag it on the listing.